Xifaxan vs. Bentyl

Are Xifaxan and Bentyl the Same Thing?

Xifaxan (rifaximin) and Bentyl (dicyclomine) are used to treat diarrhea from different causes and non-constipating irritable bowel syndrome (IBS).

Xifaxan is used to treat patients 12 years of age and older with travelers' diarrhea caused by noninvasive strains of Escherichia coli (E. coli).

Xifaxan and Bentyl that belong to different drug classes. Xifaxan is an antibiotic and Bentyl is an anticholinergic.

Side effects of Xifaxan and Bentyl that are similar include nausea, vomiting, constipation, bloating, headache, and dizziness.

Side effects of Xifaxan that are different from Bentyl include gas, stomach pain, feeling like you need to urgently empty your bowel, feeling your bowel is not completely empty, tired feeling, and swelling in your hands, feet, or torso.

Side effects of Bentyl that are different from Xifaxan include dry mouth, blurred vision, dry eyes, confusion, agitation, increased heart rate, difficulty urinating, nervousness, drowsiness, weakness, lightheadedness, flushing, rash, and stuffy nose.

Xifaxan may interact with cyclosporine, ketoconazole, warfarin, antibiotics, antiviral medicines, and heart or blood pressure medicines.

Bentyl may interact with alcohol, other medicines that make you sleepy (cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, and medicines for seizures, depression, or anxiety), amantadine, digoxin, metoclopramide, atropine,

belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, heart rhythm medications, irritable bowel medications, MAO inhibitors, nitrate medications, phenothiazines steroids, and ulcer medications.

What Are Possible Side Effects of Xifaxan?

Side effects of Xifaxan include:

  • nausea,
  • vomiting,
  • constipation,
  • bloating,
  • gas,
  • stomach pain,
  • feeling like you need to urgently empty your bowel,
  • feeling your bowel is not completely empty,
  • headache,
  • dizziness,
  • tired feeling, or
  • swelling in your hands, feet, or torso.

Tell your doctor if you develop serious side effects of Xifaxan including:

What Are Possible Side Effects of Bentyl?

Common side effects of Bentyl include:

  • dry mouth,
  • blurred vision,
  • dry eyes,
  • confusion,
  • agitation,
  • increased heart rate,
  • constipation,
  • difficulty urinating,
  • headache,
  • nervousness,
  • drowsiness,
  • weakness,
  • dizziness,
  • lightheadedness,
  • flushing,
  • nausea,
  • vomiting,
  • rash,
  • stuffy nose, and
  • abdominal bloating

What Is Xifaxan?

Xifaxan (rifaximin) is an antibiotic indicated for the treatment of patients 12 years of age and older with travelers' diarrhea caused by noninvasive strains of Escherichia coli (E. coli), and to lower the risk of worsened brain function, or hepatic encephalopathy, in adults with liver failure.

What Is Bentyl?

Bentyl (dicyclomine) is an anticholinergics prescribed for irritable bowel syndrome (IBS).

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Digestive Disorders: Common Misconceptions See Slideshow

What Drugs Interact With Xifaxan?

Xifaxan may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Bentyl?

Bentyl may interact with amantadine, MAO inhibitors, phenothiazines, or antidepressants.

Bentyl may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, or anxiety), digoxin, metoclopramide, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, heart rhythm medications, irritable bowel medications, nitrates, steroids, or ulcer medications.

How Should Xifaxan Be Taken?

Xifaxan (rifaximin) tablets for oral administration are film-coated and contain 200 or 550 mg of rifaximin. Usual dosage is 200 mg three times a day for three days for diarrhea and 550mg twice a day for 3 days for hepatic encephalopathy.

How Should Bentyl Be Taken?

The usual doses of Bentyl range from from 20 - 40 mg given 4 times daily.

QUESTION

What is irritable bowel syndrome or IBS? See Answer
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References

Salix Pharmaceuticals. Xifaxan Drug Information.
https://www.xifaxan.com
FDA. Bentyl Prescribing Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/007409s041lbl.pdf

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