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Zebeta vs. Bystolic

Reviewed on 12/2/2019

Are Zebeta and Bystolic the Same Thing?

Zebeta (bisoprolol fumarate) and Bystolic (nebivolol) are beta-adrenergic receptor blocking agents (beta-blockers) used to treat hypertension (high blood pressure).

Side effects of Zebeta and Bystolic that are similar include tiredness, slow heartbeat, dizziness, nausea, stomach pain, diarrhea, and sleep problems (insomnia).

Side effects of Zebeta that are different from Bystolic include drowsiness, lightheadedness on standing, spinning sensation, dry mouth, vomiting, constipation, increased urination, runny or stuffy nose, ringing in your ears, weakness, depression, anxiety, restless feeling, joint or muscle pain, itching or skin rash, or loss of interest in sex.

Side effects of Bystolic that are different from Zebeta include headache, fatigue, numbness or a cold feeling in your hands and feet, shortness of breath, rash, or fluid retention in the legs.

Both Zebeta and Bystolic may interact with other beta-blockers, heart medicines, clonidine, digitalis, or heart rhythm medicines.

Zebeta may also interact with guanethidine, rifampin, insulin or diabetes medication you take by mouth, and medicine for asthma or other breathing disorders.

Bystolic may also interact with cimetidine, isoniazid, methimazole, reserpine, ropinirole, ticlopidine, antibiotics, antidepressants, anti-malaria medications, blood pressure medicines, HIV/AIDS medicines, or medicines to treat psychiatric disorders.

What Are Possible Side Effects of Zebeta?

Common side effects of Zebeta include:

  • tiredness,
  • drowsiness,
  • slow heartbeat,
  • lightheadedness upon standing,
  • dizziness,
  • spinning sensation,
  • dry mouth,
  • nausea,
  • vomiting,
  • stomach pain,
  • diarrhea,
  • constipation,
  • increased urination,
  • runny or stuffy nose,
  • ringing in your ears,
  • weakness,
  • sleep problems (insomnia),
  • depression,
  • anxiety,
  • restless feeling,
  • joint or muscle pain,
  • itching or skin rash, or
  • loss of interest in sex.

Tell your doctor if you experience unlikely but serious side effects of Zebeta including:

  • very slow heartbeat,
  • severe dizziness,
  • fainting,
  • blue fingers/toes,
  • trouble breathing, or
  • mental/mood changes (such as confusion, mood swings, depression).

What Are Possible Side Effects of Bystolic?

Common side effects of Bystolic include:

  • agitation,
  • nervousness,
  • anxiety,
  • seizures (convulsions),
  • skin rash,
  • dizziness,
  • spinning sensation,
  • hallucinations,
  • fever,
  • fast heart rate,
  • overactive reflexes,
  • nausea,
  • vomiting,
  • upset stomach,
  • diarrhea,
  • constipation,
  • loss of coordination,
  • headache,
  • drowsiness, and
  • fainting.

What Is Zebeta?

Zebeta (bisoprolol fumarate) is a type of antihypertensive drug called a beta-adrenergic receptor blocking agent (beta blocker) used to treat hypertension (high blood pressure).

What Is Bystolic?

Bystolic (nebivolol) is a beta-blocker indicated for the treatment of high blood pressure (hypertension).

QUESTION

Salt and sodium are the same. See Answer

What Drugs Interact With Zebeta?

Zebeta may interact with other medications including other beta blockers, heart medicines, clonidine, digitalis, disopyramide, guanethidine, rifampin, insulin or diabetes medication you take by mouth, and medicine for asthma or other breathing disorders.

What Drugs Interact With Bystolic?

Bystolic may interact with other heart or blood pressure medications.

Bystolic may also interact with cimetidine, clonidine, digitalis, isoniazid, methimazole, reserpine, ropinirole, ticlopidine, other beta-blockers, antibiotics, antidepressants, anti-malaria medications, heart rhythm medicines, HIV or AIDS medicines, and medicines to treat psychiatric disorders.

How Should Zebeta Be Taken?

The dose of Zebeta is individualized to the needs of the patient, ranging from 2.5 to 20 mg once daily.

How Should Bystolic Be Taken?

The dose of Bystolic is individualized to the needs of the patient. For most patients, the recommended starting dose of Bystolic is 5 mg once daily, with or without food, as monotherapy or in combination with other agents.

SLIDESHOW

How to Lower Blood Pressure: Exercise Tips See Slideshow

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References
SOURCE:

FDA. Zebeta Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019982s014lbl.pdf

Allergan. Bystolic Product Information.

https://www.bystolic.com

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