Acétate de Zinc, Acexamate de Zinc, Aspartate de Zinc, Atomic Number 30, Chlorure de Zinc, Citrate de Zinc, Gluconate de Zinc, Méthionine de Zinc, Monométhionine de Zinc, Numéro Atomique 30, Orotate de Zinc, Oxyde de Zinc, Picolinate de Zinc, Pyrithione de Zinc, Sulfate de Zinc, Zinc Acetate, Zinc Acexamate, Zinc Aspartate, Zinc Chloride, Zinc Citrate, Zinc Difumarate Hydrate, Zinc Gluconate, Zinc Methionine, Zinc Monomethionine, Zinc Murakab, Zinc Orotate, Zinc Oxide, Zinc Picolinate, Zinc Pyrithione, Zinc Sulfate, Zinc Sulphate, Zincum Aceticum, Zincum Gluconicum, Zincum Metallicum, Zincum Valerianicum, Zn.
Zinc is a mineral. It is called an "essential trace element" because very small amounts of zinc are necessary for human health. Since the human body does not store excess zinc, it must be consumed regularly as part of the diet. Common dietary sources of zinc include red meat, poultry, and fish. Zinc deficiency can cause short stature, reduced ability to taste food, and the inability of testes and ovaries to function properly.
Zinc is taken by mouth for the treatment and prevention of zinc deficiency and its consequences, including stunted growth and acute diarrhea in children, slow wound healing, and Wilson's disease.
It is also used for boosting the immune system, improving growth and heath in zinc deficient infants and children, for treating the common cold and recurrent ear infections, the flu, upper respiratory tract infections, preventing and treating lower respiratory infections, swine flu, ringing in the ears, and severe head injuries. It is also used for malaria and other diseases caused by parasites.
Some people use zinc for an eye disease called macular degeneration, for night blindness, and for cataracts. It is also used for asthma; diabetes and associated nerve damage; high blood pressure; AIDS/HIV, AIDS/HIV-related pregnancy complications; HIV-related diarrhea and AIDS diarrhea-wasting syndrome, AIDS-related infections, and high levels of bilirubin in blood (hyperbilirubinemia).
It is also taken by mouth anorexia nervosa, obsessive-compulsive disorder, depression, dementia, dry mouth, attention deficit-hyperactivity disorder (ADHD), blunted sense of taste (hypogeusia), hepatic encephalopathy, alcohol-related liver disease, Crohn's disease, ulcerative colitis, inflammatory bowel disease, canker sores, stomach ulcers, leg ulcers, and bed sores.
Zinc is taken by mouth for osteoporosis, rheumatoid arthritis, psoriatic arthritis, warts, and muscle cramps in people with liver disease. It is also used for sickle cell disease, itching, rosacea, hair loss, psoriasis, eczema, acne, a blood disorder called thalassemia, Alzheimer's disease, Down syndrome, Hansen's disease, and cystic fibrosis.
It is also taken by mouth for cancer prevention, including esophageal cancer, colon and rectal cancer, stomach cancer, brain cancer, head and neck cancer recurrence, nasal and throat cancer recurrence, and non-Hodgkin's lymphoma. Zinc is used by mouth to prevent inflammation in the lining of the digestive tract, chemotherapy-related complications, anemia, pregnancy-related complications including iron deficiency, vitamin A deficiency (taken with vitamin A), arsenic poisoning, chronic obstructive pulmonary disease (COPD), clogged arteries, leukemia, burns, diaper rash, leprosy, and skin lesions caused by leishmania infection.
Some athletes use zinc by mouth for improving athletic performance and strength.
Zinc is also applied to the skin for treating acne, foot ulcers caused by diabetes, leg ulcers, diaper rash, warts, aging skin, brown patches on the face, herpes simplex infections, parasitic infections, and to speed wound healing. Zinc is also applied to the anus for people with problems controlling bowel movements.
Zinc citrate is used in toothpaste and mouthwash to prevent dental plaque formation and gingivitis. Zinc is also used in chew gum, candies, and mouth rinses to treat bad breath.
There is a zinc preparation that can be sprayed in the nostrils for treating the common cold.
Zinc sulfate is used in eye drop solutions to treat eye irritation.
Zinc is injected into the vein to improve nutrition in people recovering from burns.
Note that many zinc products also contain another metal called cadmium. This is because zinc and cadmium are chemically similar and often occur together in nature. Exposure to high levels of cadmium over a long time can lead to kidney failure. The concentration of cadmium in zinc-containing supplements can vary as much as 37-fold. Look for zinc-gluconate products. Zinc gluconate consistently contains the lowest cadmium levels.
How does it work?
Zinc is needed for the proper growth and maintenance of the human body. It is found in several systems and biological reactions, and it is needed for immune function, wound healing, blood clotting, thyroid function, and much more. Meats, seafood, dairy products, nuts, legumes, and whole grains offer relatively high levels of zinc.
Zinc deficiency is not uncommon worldwide, but is rare in the US. Symptoms include slowed growth, low insulin levels, loss of appetite, irritability, generalized hair loss, rough and dry skin, slow wound healing, poor sense of taste and smell, diarrhea, and nausea. Moderate zinc deficiency is associated with disorders of the intestine which interfere with food absorption (malabsorption syndromes), alcoholism, chronic kidney failure, and chronic debilitating diseases.
Zinc plays a key role in maintaining vision, and it is present in high concentrations in the eye. Zinc deficiency can alter vision, and severe deficiency can cause changes in the retina (the back of the eye where an image is focused).
Zinc might also have effects against viruses. It appears to lessen symptoms of the rhinovirus (common cold), but researchers can't yet explain exactly how this works. In addition, there is some evidence that zinc has some antiviral activity against the herpes virus.
- Zinc deficiency. Zinc deficiency might occur in people with severe diarrhea, conditions that make it hard for the bowel to absorb food, liver cirrhosis, and alcoholism. It may also occur after major surgery and during long-term use of tube feeding in the hospital. Taking zinc by mouth or giving zinc intravenously (by IV) helps to restore zinc levels in people who are zinc deficient. However, taking zinc supplements regularly is not recommended.
Likely Effective for...
- Diarrhea. Taking zinc by mouth reduces the duration and severity of diarrhea in children who are undernourished or zinc deficient. Severe zinc deficiency in children is common in developing countries. Also giving zinc to undernourished women during pregnancy and continuteing until one month postpartum reduces the incidence of diarrhea in infants during the first year of life.
- An inherited disorder called Wilson's disease. Taking zinc by mouth improves symptoms of an inherited disorder called Wilson's disease. People with Wilson's disease have too much copper in their bodies. Zinc blocks how much copper is absorbed and increases how much copper the body releases.
Possibly Effective for...
- Acne. Research suggests that people with acne have lower blood and skin levels of zinc. Taking zinc by mouth appears to help treat acne. However, it's unclear how beneficial zinc is compared to acne medications such as tetracycline or minocycline. Applying zinc to the skin in an ointment does not seem to help treat acne unless used in combination with the antibiotic drug called erythromycin.
- An inherited disorder that affects zinc uptake (acrodermatitis enteropathica). Taking zinc by mouth seems to help improve symptoms of acrodermatitis enteropathica.
- Age-related vision loss (age-related macular degeneration). People who consume more zinc as part of their diet seem to have a lower risk of developing age-related vision loss. Research shows that taking supplements containing zinc and antioxidant vitamins may modestly slow vision loss and prevent age-related vision loss from becoming advanced in people at high risk. It's still not clear if taking zinc along with antioxidant vitamins helps prevent age-related vision loss from becoming advanced in people at low risk. Most research shows that taking zinc alone, without antioxidant vitamins, does not help most people with age-related vision loss. However, it's possible that people with certain genes that make them susceptible to age-related vision loss might benefit from zinc supplements.
- Anorexia. Taking zinc supplements by mouth might help increase weight gain and improve depression symptoms in teens and adults with anorexia.
- Attention deficit-hyperactivity disorder (ADHD). Taking zinc by mouth in combination with conventional treatment might slightly improve hyperactivity, impulsiveness, and socialization problems in some children with ADHD. However, zinc does not seem to improve attention span. Some research suggests that children with ADHD have lower zinc levels in their blood than children without ADHD. Other research suggests people with ADHD with lower zinc levels might not respond well enough to prescription medications for ADHD (stimulants). Studies using zinc for ADHD have taken place in the Middle East where zinc deficiency is relatively common compared to Western countries. It is not known if zinc would have the same potential benefits when used for ADHD in people from Western countries.
- Burns. Giving zinc intravenously (by IV) together with other minerals seems to improve wound healing in people with burns. However, taking zinc alone does not appear to improve wound healing in all people with burns, but it might reduce recovery time in people with severe burns.
- Tumors in the rectum and colon. Research suggests that taking a supplement containing selenium, zinc, vitamin A 2, vitamin C, and vitamin E by mouth daily for 5 years reduces the risk of recurrent large-bowel tumors by about 40%.
- Common cold. Although some conflicting results exist, most research shows that taking lozenges containing zinc gluconate or zinc acetate by mouth helps reduce the duration of a cold in adults. However, side effects such as bad taste and nausea might limit its usefulness. It is unclear if zinc helps prevent common colds. In adults, taking zinc supplements by mouth does not seem to prevent common colds. However, zinc gluconate lozenges might help prevent colds in children and adolescents. Using zinc as a nose spray does not seem to help prevent colds.
- Depression. Population research suggests that zinc levels are lower in people with depression. Some research suggests that taking zinc along with antidepressants improves depression in people with major depression. However, other research shows that it improves depression in only people who do not respond to treatment with antidepressants alone. It doesn't seem to improve depression in people who respond to antidepressant treatment.
- Foot ulcers due to diabetes. Research suggests that applying zinc hyaluronate gel can help foot ulcers heal faster than conventional treatment in people with diabetes.
- Diaper rash. Giving zinc gluconate by mouth to infants seems to speed up the healing of diaper rash. Applying zinc oxide paste also seems to improve the healing of diaper rash. However, it doesn't seem to work as well as applying 2% eosin solution.
- Gingivitis. Using toothpastes containing zinc, with or without an antibacterial agent, appears to prevent plaque and gingivitis. Some evidence also shows that zinc-containing toothpaste can reduce existing plaque. However, other conventional treatments may be more effective. Also, most studies that showed benefit used zinc citrate in combination with triclosan, which is not available in the US.
- Bad breath. Research suggests that chewing gum, sucking on a candy, or using a mouth rinse containing zinc reduces bad breath.
- Herpes simplex virus. Applying zinc sulfate or zinc oxide to the skin, alone or with other ingredients, seems to reduce the duration and severity of oral and genital herpes. However, zinc might not be beneficial for recurrent herpes infections.
- Taste disorder (hypogeusia). Some early research suggests that taking zinc by mouth does not improve taste disorders in children with zinc deficiency. But most evidence suggests that taking zinc by mouth is effective for people with a reduced ability to taste foods due to zinc deficiency or some other conditions.
- Skin lesions (Leishmania lesions). Research suggests that taking zinc sulfate by mouth or injecting as a solution into lesions helps heal lesions in people with Leishmaniasis. However, injecting zinc solutions into lesions does not seem to be more effective than conventional treatments.
- Leprosy. Taking zinc by mouth in combination with anti-leprosy drugs seems to help treat leprosy.
- Muscle cramps. Taking zinc by mouth seems to help treat muscle cramps in people with cirrhosis and zinc deficiency.
- Weak bones (osteoporosis). Low zinc intake seems to be linked to lower bone mass. Taking a zinc supplement in combination with copper, manganese, and calcium might decrease bone loss in women who have passed menopause.
- Peptic ulcers. Taking zinc acexamate by mouth seems to help treat and prevent peptic ulcers. However, this form of zinc is not available in the US.
- Pneumonia. Most research suggests that taking zinc might help PREVENT pneumonia in undernourished children. However, research assessing the effects of zinc for TREATING pneumonia once it develops shows conflicting.
- Complications during pregnancy. Taking zinc by mouth during pregnancy appears to reduce the risk for early delivery by 14%. However, zinc supplementation does not seem to reduce the risk for stillbirths or infant deaths. Taking zinc with vitamin A might help restore night vision in pregnant women affected by night blindness. However, taking zinc alone does not appear to have this effect.
- Bed sores. Applying zinc paste appears to help improve the healing of bed sores in elderly people. Also, increasing zinc intake in the diet seems to improve bed sore healing in hospitalized patients with bed sore.
- Food poisoning (shigellosis). Research shows that taking a multivitamin syrup containing zinc along with conventional treatment can improve recovery time and reduce diarrhea in undernourished children with food poisoning.
- Sickle cell disease. Taking zinc by mouth seems to help reduce symptoms of sickle cell disease in people with zinc deficiency. Taking zinc supplements also appears to decrease the risk for complications and infections related to sickle cell disease.
- Leg ulcers. Taking zinc sulfate by mouth appears to help some types of leg ulcers heal faster. The effects seem to be greater in people with low levels of zinc before treatment. Applying zinc paste to leg ulcers also appears to improve healing.
- Vitamin A deficiency. Taking zinc by mouth together with vitamin A seems to improve vitamin A levels in undernourished children better than vitamin A or zinc alone.
- Warts. Early research suggests that applying a zinc sulfate solution improves plane warts but not common warts. Applying zinc oxide ointment appears to be as effective as conventional treatments for curing warts. Taking zinc sulfate by mouth also appears to be effective.
Possibly Ineffective for...
- AIDS diarrhea-wasting syndrome. Taking zinc by mouth together with vitamins does not seem to improve AIDS diarrhea-wasting syndrome.
- Hair loss. Although there is early evidence that suggests taking zinc together with biotin might be helpful for hair loss, most studies suggest that zinc is not effective for this condition.
- Scaly, itchy skin (eczema). Taking zinc by mouth does not appear to improve skin redness or itching in children with eczema.
- Cataracts. Taking zinc by mouth together with antioxidant vitamins does not seem to help treat or prevent cataracts.
- Cystic fibrosis. Zinc sulfate does not appear to improve lung function in children or adolescents with cystic fibrosis, although it may reduce the need for antibiotics.
- HIV/AIDS. Taking zinc by mouth along with antiretroviral therapy does not improve immune function or reduce the risk of death in adults or children with HIV.
- Pregnancy complications in women with HIV/AIDS. Taking zinc by mouth during pregnancy does not appear to reduce the risk of transmitting HIV to the infant. Also, zinc does not appear to prevent infant death or maternal wasting in pregnant women with HIV.
- Infant development. Giving zinc to infants does not improve mental or motor development.
- Inflammatory bowel disease (IBD). Taking zinc by mouth does not seem to help treat IBD.
- Flu. Taking zinc supplements by mouth is unlikely to improve immune function against the flu virus in people who are not at risk for zinc deficiency.
- Ear infection. Taking zinc does not appear to prevent ear infections in children.
- Iron-deficiency during pregnancy. Taking zinc by mouth does not seem to help improve iron levels in women taking iron and folic acid supplements.
- Prostate cancer. Early research suggests that taking zinc along with other vitamins and minerals may prevent prostate cancer in some men. However, other research shows that taking zinc can increase the risk of developing prostate cancer and increase the risk of dying from prostate cancer.
- Red and irritated skin (psoriasis). Taking zinc by mouth does not seem to help treat psoriasis.
- Joint inflammation associated with a specific skin condition (psoriatic arthritis). Taking zinc by mouth, alone or together with painkillers, has no effect on the progression of psoriatic arthritis.
- Joint inflammation (rheumatoid arthritis). Taking zinc by mouth does not seem to help treat rheumatoid arthritis.
- Rosacea. Research suggests that taking zinc by mouth daily for 90 days does not improve quality of life or symptoms associated with rosacea.
- Sexual dysfunction. Research suggests that zinc supplementation does not improve sexual function in men with sexual dysfunction related to kidney disease.
- Ringing in the ears (tinnitus). Taking zinc by mouth does not seem to help treating ringing in the ears.
- Upper respiratory tract infections. Taking zinc by mouth does not decrease the risk for upper respiratory tract infections.
Likely Ineffective for...
- Malaria. Taking zinc by mouth does not help prevent or treat malaria in undernourished children in developing countries. But some research suggests it might reduce the risk for high fevers in children with malaria.
Insufficient Evidence to Rate Effectiveness for...
- AIDS-related infections due to weakened immunity. There is some early evidence that taking zinc supplements by mouth in combination with the drug zidovudine might reduce infections that occur because of a weakened immune system. However, it might negatively affect survival in people with AIDS.
- Alcohol-related liver disease. Taking zinc sulfate by mouth might improve liver function in people with alcohol-related liver disease.
- Alzheimer's disease. Some early research shows that zinc supplements might slow the worsening of symptoms in people with Alzheimer's disease.
- Anemia. Research suggests that giving a porridge containing zinc and other vitamins and minerals to infants reduces the risk of anemia.
- Arsenic poisoning. Early research suggests that taking zinc together with spirulina can reduce symptoms and arsenic levels in the urine and hair of people with long-term arsenic poisoning.
- Asthma. Zinc intake does not appear to be linked to the risk for developing asthma in children.
- A blood disorder called beta-thalassemia. Early research suggests that taking zinc sulfate while undergoing blood transfusions increases growth in children with beta-thalassemia compared to blood transfusions alone.
- Brain tumor. Early research suggests that zinc intake is not linked with a reduced risk of developing brain cancer.
- Canker sores. Some early research suggests that taking zinc sulfate improves canker sores and prevents them from reappearing. However, other research shows no benefit.
- Chemotherapy-related complications. Research suggests that taking zinc by mouth does not affect chemotherapy-related side effects such as nausea and vomiting in children undergoing chemotherapy for leukemia. However, it seems to reduce the number of episodes of infection.
- A lung disease called chronic obstructive pulmonary disorder (COPD). Early research suggests that taking zinc daily after recovery from COPD-related infections reduces the risk of additional infections in older people.
- Colon and rectal cancer. Population research suggests that increased zinc intake is linked to a 17% to 20% reduced risk of colorectal cancer.
- Clogged arteries (coronary artery disease). Early research suggests that taking zinc reduces cholesterol but not triglycerides in people with clogged arteries.
- Memory loss (dementia). Research suggests that taking zinc sulfate improves behavior and social abilities in people with memory loss.
- Dental plaque. Early evidence suggests that brushing teeth with toothpaste containing zinc reduces plaque buildup.
- Diabetes. Research suggests that taking zinc alone or with other nutrients reduces blood sugar in healthy people and in those with diabetes, metabolic syndrome, or obesity.
- Nerve damage caused by diabetes (diabetic neuropathy). Research suggests that taking zinc sulfate improves nerve function and reduces blood sugar in people with nerve damage caused by diabetes.
- Down syndrome. Early research suggests that taking zinc can improve immune function and reduce infections in people with Down syndrome who are zinc deficient and have weakened immune systems. However, other research shows conflicting results.
- Esophageal cancer. Early research has linked low intake of zinc with an increased risk of esophageal cancer. However, other early research shows that zinc intake is not linked with the risk of esophageal cancer. It's possible that the source of zinc (plant vs. meat) affects how beneficial it is.
- Loss of control of bowel movements. Research suggests that applying an ointment containing zinc and aluminum to the anus three times daily for 4 weeks improves symptoms and quality of life in women with a loss of control of bowel movements.
- Stomach cancer. Early research shows that increased zinc intake is not linked to a lower risk of stomach cancer.
- Head and neck cancer. Early research suggests that zinc supplementation does not improve survival rates or reduce the spread of cancer after 3 years in people with head and neck cancer.
- Loss in brain function due to liver problems (Hepatic encephalopathy). Early research suggests that taking zinc may slightly improve mental function in people with hepatic encephalopathy. However, zinc does not appear to improve disease severity or recurrence.
- HIV-related diarrhea. Taking zinc long-term might help prevent diarrhea in adults with HIV who have low blood levels of zinc. However, zinc doesn't seem to help treat diarrhea in adults with HIV-related diarrhea. In children with HIV, some research shows that taking zinc reduces the occurrence of diarrhea compared to placebo (sugar pills). But other research shows that it doesn't help prevent diarrhea compared to vitamin A.
- Fertility problems in men (impotence). Some early research suggests that zinc supplementation increases sperm count, testosterone levels, and pregnancy rates in infertile men with low testosterone levels. Other research suggests that taking zinc can improve sperm shape in men with moderate enlargement of a vein in the scrotum (grade III varicocele). However, in men with fertility problems due to diseases or medical treatment, taking zinc has produced mixed results.
- Stomach infections and parasite infestations. Taking zinc alone or along with vitamin A might help treat some, but not all, parasite infections in children in developing countries. Also, some research suggests that taking zinc with vitamin A reduces the risk for some infections. However, other research suggests that zinc does not reduce the risk for infection.
- Leukemia. Research suggests that taking zinc by mouth helps improve weight gain and reduces infection rate in children and adolescents with leukemia. However, zinc does not appear to improve nutrient levels in the body so that the body can function properly.
- Full-term newborns that are underweight.. Most research suggests that taking zinc supplements during pregnancy does not reduce the risk of having a low birth weight infant. However, adding zinc to nutritional supplementation for underweight, full-term infants in developing countries seems to decrease the risk of death and reduce the risk of some complications. Also, some research suggests that giving zinc supplementation to low birth weight infants from developing countries increases weight gain and length gain. However, zinc supplementation does not appear to improve growth in low birth weight infants from industrialized countries.
- Brown patches on the face (melasma). Research suggests that applying a solution containing zinc to the skin daily for 2 months is less effective than standard skin bleaching treatment for people with brown patches on the face.
- Nose and throat cancer. Early research suggests that taking zinc improves survival rates after 5 years in people with a rare type of advanced nose and throat cancer.
- Jaundice in newborns. Early research suggests that taking zinc twice daily for 7 days does not improve jaundice in newborns.
- Head trauma. Administering zinc immediately after a head trauma seems to improve the rate of recovery.
- A type of cancer called non-Hodgkin's lymphoma. Early research suggests that zinc supplementation is linked to a decreased risk of developing non-Hodgkin's lymphoma
- Obsessive-compulsive disorder (OCD). Early research suggests that taking zinc twice daily along with the drug fluoxetine for 8 weeks reduces OCD symptoms slightly more than taking fluoxetine alone.
- Swelling and ulcers in the mouth caused by chemotherapy, radiation therapy, or hematopoietic stem cell transplantation (HSCT). Research shows that taking zinc sulfate by mouth while undergoing radiation therapy helps prevent ulcers and swelling in the mouth caused by radiation treatments. Some research shows that taking zinc sulfate by mouth reduces the severity of mouth ulcers in adults undergoing chemotherapy. However, taking zinc does appear to improve mouth ulcers caused by chemotherapy in children and adolescents. Zinc does not appear to reduce mouth ulcers in patients undergoing hematopoietic stem cell transplantation (HSCT).
- Prostate swelling (prostatis). Research suggests that taking zinc, selenium, and iodide along with the drug ofloxacin improves symptoms of prostatitis, including pain and quality of life, compared to taking ofloxacin alone. However, taking zinc along with the drug prazosin does not seem to improve symptoms compared to taking prazosin alone.
- High bilirubin levels in the blood caused by HIV/AIDs medications. A class of antiviral medications called HIV protease inhibitors can increase levels of bilirubin in the blood. Early research suggests that taking zinc daily for 14 days decreases total bilirubin levels in the blood by 17% to 20% in people being treated with the HIV protease inhibors atazanavir/ritonavir.
- Itching. Early research suggests that taking zinc twice daily for 2 months reduces itching in people with kidney disease who are experiencing itching due to dialysis treatment.
- Recovery from surgery. Early research suggests that taking zinc reduces the healing time after surgery used to treat an abnormal skin growth located at the tailbone (pilonidal surgery).
- Wound healing. Early research suggests that applying a zinc solution twice daily improves wound healing compared to applying a saline solution. However, applying zinc-containing insulin (Humulin by Eli Lilly and Company) seems to work better than solution containing zinc alone.
- Wrinkled skin. A skin cream containing 10% vitamin C as L-ascorbic acid and acetyl tyrosine, zinc sulfate, sodium hyaluronate, and bioflavonoids (Cellex-C High Potency Serum) applied for 3 months to facial skin aged by sun exposure seems to improve fine and coarse wrinkling, yellowing, roughness, and skin tone.
- Crohn's disease.
- Ulcerative colitis.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Zinc is LIKELY SAFE for most adults when applied to the skin, or when taken by mouth in amounts not larger than 40 mg daily. Routine zinc supplementation is not recommended without the advice of a healthcare professional. In some people, zinc might cause nausea, vomiting, diarrhea, metallic taste, kidney and stomach damage, and other side effects. Using zinc on broken skin may cause burning, stinging, itching, and tingling.
Zinc is POSSIBLY SAFE when taking by mouth in doses greater than 40 mg daily. There is some concern that taking doses higher than 40 mg daily might decrease how much copper the body absorbs. Decreased copper absorption may cause anemia.
Zinc is POSSIBLY UNSAFE when inhaled through the nose, as it might cause permanent loss of smell. In June 2009, the US Food and Drug Administration (FDA) advised consumers not to use certain zinc-containing nose sprays (Zicam) after receiving over 100 reports of loss of smell. The maker of these zinc-containing nose sprays has also received several hundred reports of loss of smell from people who had used the products. Avoid using nose sprays containing zinc.
Taking high amounts of zinc is LIKELY UNSAFE. High doses above the recommended amounts might cause fever, coughing, stomach pain, fatigue, and many other problems.
Taking more than 100 mg of supplemental zinc daily or taking supplemental zinc for 10 or more years doubles the risk of developing prostate cancer. There is also concern that taking large amounts of a multivitamin plus a separate zinc supplement increases the chance of dying from prostate cancer.
Taking 450 mg or more of zinc daily can cause problems with blood iron. Single doses of 10-30 grams of zinc can be fatal.
Pregnancy and breast-feeding: Zinc is LIKELY SAFE for most pregnant and breast-feeding women when used in the recommended daily amounts (RDA). However, zinc is POSSIBLY UNSAFE when used in high doses by breast-feeding women and LIKELY UNSAFE when used in high doses by pregnant women. Pregnant women over 18 should not take more than 40 mg of zinc per day; pregnant women age 14 to 18 should not take more than 34 mg per day. Breast-feeding women over 18 should not take more than 40 mg of zinc per day; breast-feeding women age 14 to 18 should not take more than 34 mg per day.
Alcoholism: Long-term, excessive alcohol drinking is linked to poor zinc absorption in the body.
Diabetes: Large doses of zinc can lower blood sugar in people with diabetes. People with diabetes should use zinc products cautiously.
Hemodialysis: People receiving hemodialysis treatments seem to be at risk for zinc deficiency and might require zinc supplements.
HIV (human immunodeficiency virus)/AIDS: Use zinc cautiously if you have HIV/AIDS. Zinc use has been linked to shorter survival time in people with HIV/AIDs.
Syndromes in which it is difficult for the body to absorb nutrients: People with malabsorption syndromes may be zinc deficient.
Rheumatoid arthritis (RA): People with RA absorb less zinc.
Cephalexin (Keflex)Interaction Rating: Major Do not take this combination.
Cephalexin (Keflex) is an antibiotic used to treat infections. Zinc can reduce how much cephalexin (Keflex) the body absorbs if taken at the same time or 3 hours before cephalexin (Keflex). This might decrease how well cephalexin (Keflex) works for treating infections. But taking zinc 3 hours after taking cephalexin (Keflex) doesn't affect how much cephalexin (Keflex) the body absorbs. Therefore, zinc should be taken 3 hours after taking cephalexin (Keflex).
PenicillamineInteraction Rating: Major Do not take this combination.
Penicillamine is used for Wilson's disease and rheumatoid arthritis. Zinc might decrease how much penicillamine your body absorbs and decrease the effectiveness of penicillamine. Take zinc and penicillamine at least 2 hours apart.
Antibiotics (Quinolone antibiotics)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Zinc might decrease how much antibiotic the body absorbs. Taking zinc along with some antibiotics might decrease the effectiveness of some antibiotics. To avoid this interaction, take antibiotics at least 2 hours before or 4-6 hours after zinc supplements.
Some of these antibiotics that might interact with zinc include ciprofloxacin (Cipro), levofloxacin (Levaquin), ofloxacin (Floxin), moxifloxacin (Avelox), gatifloxacin (Tequin) enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), trovafloxacin (Trovan), and grepafloxacin (Raxar).
Antibiotics (Tetracycline antibiotics)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Zinc can attach to tetracyclines in the stomach. This decreases the amount of tetracyclines that can be absorbed. Taking zinc with tetracyclines might decrease the effectiveness of tetracyclines. To avoid this interaction, take tetracyclines 2 hours before or 4-6 hours after taking zinc supplements.
Atazanavir (Reyataz)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Atazanavir (Reyataz) is a drug used for HIV infection. Zinc decreases how much atazanavir (Reyataz) the body absorbs. But the body still absorbs enough atazanavir (Reyataz) for atazanvir to work for treating HIV. So this interaction is probably not a big concern.
Cisplatin (Platinol-AQ)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Cisplatin (Platinol-AQ) is used to treat cancer. Taking zinc along with EDTA and cisplatin (Platinol-AQ) might inactivate cisplatin (Platinol-AQ) therapy. It is not known for sure, though, if the amount of interference caused by zinc is significant.
Drugs used for HIV (Integrase inhibitors)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Taking zinc along with integrase inhibitors might decrease blood levels of integrase inhibitors. This might decrease their effectiveness. Talk to your healthcare provider if you are using integrase inhibitors and want to start taking zinc. Integrase inhibitors include dolutegravir (Tivicay), elvitegravir (Vitekta), and raltegravir (Isentress).
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Zinc might decrease blood sugar in people with type 2 diabetes. Diabetes medications are also used to lower blood sugar. Taking zinc along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Ritonavir (Norvir)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Ritonavir (Norvir) is a drug used for HIV infection. Zinc can reduce how much ritonavir (Norvir) the body absorbs. But this doesn't seem to decrease the effects of ritonavir very much. So this interaction is probably not a big concern.
Amiloride (Midamor)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Amiloride (Midamor) is used as a "water pill" to help remove excess water from the body. Another effect of amiloride (Midamor) is that it can increase the amount of zinc in the body. Taking zinc supplements with amiloride (Midamor) might cause you to have too much zinc in your body.
The following doses have been studied in scientific research:
- General: Recommended Dietary Allowance (RDA) quantities of zinc have been established for boys and men age 14 and older, 11 mg/day; women 19 and older, 8 mg/day; pregnant women 14 to 18, 13 mg/day; pregnant women 19 and older, 11 mg/day; lactating women 14 to 18, 14 mg/day; lactating women 19 and older, 12 mg/day. Tolerable Upper Intake Levels (UL) of zinc for people who are not receiving zinc under medical supervision: adults 19 years and older (including pregnancy and lactation), 40 mg/day. The typical North American male consumes about 13 mg/day of dietary zinc; women consume approximately 9 mg/day. Different salt forms provide different amounts of elemental zinc. Zinc sulfate contains 23% elemental zinc; 220 mg zinc sulfate contains 50 mg zinc. Zinc gluconate contains 14.3% elemental zinc; 10 mg zinc gluconate contains 1.43 mg zinc.
- For zinc deficiency: In people with mild zinc deficiency, recommendations suggest taking two to three times the recommended dietary allowance (RDA) of zinc for 6 months. In people with moderate to severe deficiency, recommendations suggest taking four to five times the RDA for 6 months.
- For diarrhea: To prevent diarrhea in infants, pregnant women have used 15 mg of zinc, with or without 60 mg of iron and 250 mcg of folic acid, starting 10-24 weeks into pregnancy through one month after giving birth.
- For treating Wilson's disease: Zinc acetate (Galzin in the U.S.; Wilzin in Europe) is an FDA-approved drug for treating Wilson's disease. The recommended dose, which contains 25-50 mg of zinc, is to be taken three to five times daily.
- For treating acne: 30-150 mg elemental zinc daily has been used.
- For an inherited disorder that affects zinc uptake (acrodermatitis enteropathica): Taking 2-3 mg/kg of elemental zinc daily for a lifetime is recommended for treating an inherited disorder that affects zinc uptake.
- For age-related vision loss (age-related macular degeneration): A combination of 80 mg of elemental zinc, 2 mg of copper, 500 mg of vitamin C, 400 IU of vitamin E, and 15 mg of beta-carotene taken daily for 5 years has been used in people with advanced age-related vision loss.
- For the eating disorder anorexia nervosa: 14-50 mg of elemental zinc has been used daily.
- For tumors in the colon and rectum: A combination supplement containing 200 mcg of selenium, 30 mg of zinc, 2 mg of vitamin A, 180 mg of vitamin C, and 30 mg of vitamin E has been taken daily for up to 5 years.
- For treating the common cold: One zinc gluconate or acetate lozenge, providing 4.5-24 mg elemental zinc, dissolved in the mouth every two hours while awake when cold symptoms are present.
- For depression: 25 mg of elemental zinc has been used daily for 12 weeks along with antidepressant medications.
- For taste disorder (hypogeusia): 140-450 mg of zinc gluconate has been taken in up to three divided doses daily for up to 4 months. Also, 25 mg of elemental zinc taken daily for 6 weeks has been used. A zinc-containing product called polaprezinc (Promac, Zeria Pharmaceutical Co., Ltd) has also been used.
- For skin lesions (leishmania lesions): 2.5-10 mg/kg of zinc sulfate has been taken in three divided doses daily for 45 days.
- For muscle cramps: 220 mg of zinc sulfate has been taken twice daily for 12 weeks.
- For osteoporosis: A combination of 15 mg of zinc combined with 5 mg of manganese, 1000 mg of calcium, and 2.5 mg of copper has been used.
- For stomach ulcers: 300-900 mg of zinc acexamate has been taken in one to three divided doses daily for up to one year. Also, 220 mg of zinc sulfate has been taken three times daily for 3-6 weeks.
- For pregnancy-related complications: 25 mg of zinc has been taken daily in combination with vitamin A for 3 weeks to restore vision in pregnant women with night blindness.
- For bed sores: A standard hospital diet plus 9 grams of arginine, 500 mg of vitamin C, and 30 mg of zinc has been used daily for 3 weeks.
- For sickle cell disease: 220 mg of zinc sulfate three times daily has been used. Also, 50-75 mg of elemental zinc taken daily in up to two divided doses for 2-3 years has been used.
- For leg ulcers: 220 mg of zinc sulfate taken three times daily has been used along with ulcer dressings.
- For warts: 400-600 mg of zinc sulfate daily for 2-3 months.
- For acne vulgaris: Zinc acetate 1.2% with erythromycin 4% as a lotion applied twice daily.
- For foot ulcers due to diabetes: A zinc hyaluronate gel has been applied once daily to ulcers until healed.
- For gingivitis: Toothpaste containing 0.2% to 2% zinc citrate alone or with sodium monofluorophosphate or 0.2% triclosan, have been used at least two times daily for up to 7 months. A mouth rinse containing 0.4% zinc sulfate and 0.15% triclosan has also been used.
- For bad breath: Two zinc-containing mouth rinses called Halita and Meridol have been used as single doses or twice daily for 7 days. Candies and chewing gums containing zinc have also been used.
- For herpes simplex infections: Zinc sulfate 0.025% to 0.25% applied 8 to 10 times daily or zinc oxide 0.3% with glycine applied every 2 hours while awake has been used. Specific products containing zinc (Virudermin Gel, Robugen GmbH, SuperLysine Plus +, Quantum Health, Inc., Herpigon) have also been used.
- For bed sores: A zinc oxide paste has applied daily along with standard care for 8-12 weeks.
- For leg ulcers: A paste containing zinc oxide 25% has been applied as a dressing once daily for the first 14 days of treatment and every third day thereafter for 8 weeks.
- For warts: A zinc oxide 20% ointment has been applied twice daily for 3 months or until cured. Zinc sulfate 5% to 10% has been applied to the skin three times daily for 4 weeks..
- For burns: An injectable solution containing 59 mcmol of copper, 4.8 mcmol of selenium, and 574 mcmol of zinc has been used for 14-21 days.
- For taste disorder (hypogeusia): A zinc solution has been added to 10 L of commercially available dialysis concentrate for 12 weeks.
- For skin lesions (leishmania lesions): An injection of zinc sulfate 2% for 6 weeks has been used.
- General: The Institute of Medicine has established Adequate Intake (AI) levels of zinc for infants birth to 6 months is 2 mg/day. For older infants and children, Recommended Dietary Allowance (RDA) quantities of zinc have been established: infants and children 7 months to 3 years, 3 mg/day; 4 to 8 years, 5 mg/day; 9 to 13 years, 8 mg/day; girls 14 to 18 years, 9 mg/day. The Tolerable Upper Intake Levels (UL) of zinc for people who are not receiving zinc under medical supervision: Infants birth to 6 months, 4 mg/day; 7 to 12 months, 5 mg/day; children 1 to 3 years, 7 mg/day; 4 to 8 years, 12 mg/day; 9 to 13 years, 23 mg/day; and 14 to 18 years (including pregnancy and lactation), 34 mg/day.
- For an inherited disorder that affects zinc uptake (acrodermatitis enteropathica): Taking 2-3 mg/kg of elemental zinc daily for a lifetime is recommended for treating an inherited disorder that affects zinc uptake.
- For the eating disorder anorexia nervosa: 14-50 mg of elemental zinc has been used daily.
- For treating attention deficit-hyperactivity disorder (ADHD): 55-150 mg of zinc sulfate containing 15-40 mg of elemental zinc has been taken daily for 6-12 weeks.
- For treating the common cold: One lozenge containing 10-23 mg of zinc gluconate, dissolved in the mouth every two hours has been used for up to 10 days. A syrup containing 15 mg of zinc has also been used twice daily for up to 10 days.
- For diaper rash: 10 mg of zinc has been taken daily from the first or second day of life until 4 months of age.
- For diarrhea: 10-40 mg of elemental zinc has been taken daily for 7-15 days to treat diarrhea in malnourished or zinc-deficient children.
- For skin lesions (leishmania lesions): 2.5-10 mg/kg of zinc sulfate taken in three divided doses daily has been used for 45 days.
- For pneumonia: In developing countries, 10-70 mg of elemental zinc has been taken daily in undernourished children aged 3 months to 5 years. Also, 2 mg/kg of zinc sulfate has been taken daily in two divided doses for 5 days.
- For food poisoning (shigellosis): Multivitamin syrup containing 20 mg of elemental zinc has been used in two divided doses daily for 2 weeks.
- For sickle cell disease: 10 mg of elemental zinc has been taken daily for one year in children 4-10 years of age. Also, 15 mg of elemental zinc has been taken twice daily for one year in boys aged 14-18 years.
- For leg ulcers: 220 mg of zinc sulfate has been used three times daily along with ulcer dressings.
- For vitamin A deficiency: 20 mg of elemental zinc has been taken daily for 14 days, with 200,000 IU of vitamin A on day 14, has been used in children 1-3 years of age.
- For acne: Zinc acetate 1.2% with erythromycin 4% as a lotion applied twice daily for 12-40 weeks.
- For diaper rash: A zinc oxide paste containing allantoin 0.5%, cod liver oil 17%, and zinc oxide 47% has been used for 5 days.
- For skin lesions (leishmania lesions): An injection of zinc sulfate 2% for 6 weeks has been used.
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Aamodt, R. L., Rumble, W. F., Johnston, G. S., Foster, D., and Henkin, R. I. Zinc metabolism in humans after oral and intravenous administration of Zn-69m. Am J Clin Nutr 1979;32(3):559-569. View abstract.
Abba, K., Gulani, A., and Sachdev, H. S. Zinc supplements for preventing otitis media. Cochrane.Database.Syst.Rev. 2010;(2):CD006639. View abstract.
Abdolsamadi, H. and Hamian, M. An investigation on therapeutic effect of zinc sulfate in patients with geographic tongue. J Dent 2006;18(4):63.
Abdulhamid, I., Beck, F. W., Millard, S., Chen, X., and Prasad, A. Effect of zinc supplementation on respiratory tract infections in children with cystic fibrosis. Pediatr.Pulmonol. 2008;43(3):281-287. View abstract.
Addy, M., Richards, J., and Williams, G. Effects of a zinc citrate mouthwash on dental plaque and salivary bacteria. J.Clin.Periodontol. 1980;7(4):309-315. View abstract.
Afkhami-Ardekani, M., Karimi, M., Mohammadi, S. M., and Nourani, F. Effect of zinc supplementation on lipid and glucose in type 2 diabetic patients. Pak J Nutr 2008;7:550-553.
Agren, M. S. and Stromberg, H. E. Topical treatment of pressure ulcers. A randomized comparative trial of Varidase and zinc oxide. Scand.J.Plast.Reconstr.Surg. 1985;19(1):97-100. View abstract.
Aigner, M., Treasure, J., Kaye, W., and Kasper, S. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of eating disorders. World J.Biol.Psychiatry 2011;12(6):400-443. View abstract.
Al Sonboli, N., Gurgel, R. Q., Shenkin, A., Hart, C. A., and Cuevas, L. E. Zinc supplementation in Brazilian children with acute diarrhoea. Ann.Trop.Paediatr. 2003;23(1):3-8. View abstract.
Al-Bader, A., Omu, A. E., and Dashti, H. Chronic cadmium toxicity to sperm of heavy cigarette smokers: immunomodulation by zinc. Arch Androl 1999;43(2):135-140. View abstract.
Al-Gurairi, F. T., Al-Waiz, M., and Sharquie, K. E. Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial. Br.J Dermatol. 2002;146(3):423-431. View abstract.
Alcala-Santaella, R., Castellanos, D., Velo, J. L., and Gonzalez, Lara, V. Zinc acexamate in treatment of duocenal ulcer. Lancet 7-20-1985;2(8447):157. View abstract.
Allen, J. I., Korchik, W., Kay, N. E., and McClain, C. J. Zinc and T-lymphocyte function in hemodialysis patients. Am J Clin Nutr 1982;36(3):410-415. View abstract.
Anderson, R. A., Roussel, A. M., Zouari, N., Mahjoub, S., Matheau, J. M., and Kerkeni, A. Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. J.Am.Coll.Nutr. 2001;20(3):212-218. View abstract.
Arad, A., Mimouni, D., Ben Amitai, D., Zeharia, A., and Mimouni, M. Efficacy of topical application of eosin compared with zinc oxide paste and corticosteroid cream for diaper dermatitis. Dermatology 1999;199(4):319-322. View abstract.
Arcasoy, A., Cavdar, A., Cin, S., Erten, J., Babacan, E., Gozdasoglu, S., and Akar, N. Effects of zinc supplementation on linear growth in beta-thalassemia (a new approach). Am J Hematol. 1987;24(2):127-136. View abstract.
Arda, H. N., Tuncel, U., Akdogan, O., and Ozluoglu, L. N. The role of zinc in the treatment of tinnitus. Otol.Neurotol. 2003;24(1):86-89. View abstract.
Arnold, L. E., Disilvestro, R. A., Bozzolo, D., Bozzolo, H., Crowl, L., Fernandez, S., Ramadan, Y., Thompson, S., Mo, X., Abdel-Rasoul, M., and Joseph, E. Zinc for attention-deficit/hyperactivity disorder: placebo-controlled double-blind pilot trial alone and combined with amphetamine. J Child Adolesc.Psychopharmacol. 2011;21(1):1-19. View abstract.
Arnold, L. E., Pinkham, S. M., and Votolato, N. Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? J Child Adolesc.Psychopharmacol 2000;10(2):111-117. View abstract.
Arsenault, J. E., Lopez de, Romana D., Penny, M. E., Van Loan, M. D., and Brown, K. H. Additional zinc delivered in a liquid supplement, but not in a fortified porridge, increased fat-free mass accrual among young Peruvian children with mild-to-moderate stunting. J Nutr 2008;138(1):108-114. View abstract.
Awasthi, S. Zinc supplementation in acute diarrhea is acceptable, does not interfere with oral rehydration, and reduces the use of other medications: a randomized trial in five countries. J Pediatr.Gastroenterol.Nutr 2006;42(3):300-305. View abstract.
Baatenburg, de Jong and Admiraal, H. Comparing cost per use of 3M Cavilon No Sting Barrier Film with zinc oxide oil in incontinent patients. J.Wound.Care 2004;13(9):398-400. View abstract.
Bahl, R., Bhandari, N., Saksena, M., Strand, T., Kumar, G. T., Bhan, M. K., and Sommerfelt, H. Efficacy of zinc-fortified oral rehydration solution in 6- to 35-month-old children with acute diarrhea. J Pediatr. 2002;141(5):677-682. View abstract.
Balogh, Z., El-Ghobarey, A. F., Fell, G. S., Brown, D. H., Dunlop, J., and Dick, W. C. Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis. Ann.Rheum.Dis. 1980;39(4):329-332. View abstract.
Bansal, A., Parmar, V. R., Basu, S., Kaur, J., Jain, S., Saha, A., and Chawla, D. Zinc supplementation in severe acute lower respiratory tract infection in children: a triple-blind randomized placebo controlled trial. Indian J Pediatr. 2011;78(1):33-37. View abstract.
Bao, B., Prasad, A. S., Beck, F. W., Fitzgerald, J. T., Snell, D., Bao, G. W., Singh, T., and Cardozo, L. J. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent. Am J Clin Nutr 2010;91(6):1634-1641. View abstract.
Bao, B., Prasad, A. S., Beck, F. W., Snell, D., Suneja, A., Sarkar, F. H., Doshi, N., Fitzgerald, J. T., and Swerdlow, P. Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients. Transl.Res 2008;152(2):67-80. View abstract.
Baqui, A. H., Zaman, K., Persson, L. A., El, Arifeen S., Yunus, M., Begum, N., and Black, R. E. Simultaneous weekly supplementation of iron and zinc is associated with lower morbidity due to diarrhea and acute lower respiratory infection in Bangladeshi infants. J Nutr 2003;133(12):4150-4157. View abstract.
Barcia, P. J. Lack of acceleration of healing with zinc sulfate. Ann.Surg. 1970;172(6):1048-1050. View abstract.
Bartlett, H. E. and Eperjesi, F. Effect of lutein and antioxidant dietary supplementation on contrast sensitivity in age-related macular disease: a randomized controlled trial. Eur.J.Clin.Nutr. 2007;61(9):1121-1127. View abstract.
Bates, C. J., Evans, P. H., Dardenne, M., Prentice, A., Lunn, P. G., Northrop-Clewes, C. A., Hoare, S., Cole, T. J., Horan, S. J., Longman, S. C., and . A trial of zinc supplementation in young rural Gambian children. Br.J.Nutr. 1993;69(1):243-255. View abstract.
Bath-Hextall, F. J., Jenkinson, C., Humphreys, R., and Williams, H. C. Dietary supplements for established atopic eczema. Cochrane.Database.Syst.Rev. 2012;2:CD005205. View abstract.
Baum, M. K., Lai, S., Sales, S., Page, J. B., and Campa, A. Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults. Clin Infect.Dis. 6-15-2010;50(12):1653-1660. View abstract.
Beale, R. J., Sherry, T., Lei, K., Campbell-Stephen, L., McCook, J., Smith, J., Venetz, W., Alteheld, B., Stehle, P., and Schneider, H. Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, controlled, double-blind trial. Crit Care Med. 2008;36(1):131-144. View abstract.
Bellamy, P. G., Jhaj, R., Mussett, A. J., Barker, M. L., Klukowska, M., and White, D. J. Comparison of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice and a zinc citrate dentifrice on plaque formation measured by digital plaque imaging (DPIA) with white light illumination. J Clin Dent. 2008;19(2):48-54. View abstract.
Belluzzi, A., Brignola, C., Campieri, M., Gionchetti, P., Rizzello, F., Boschi, S., Cunanne, S., Miglioli, M., and Barbara, L. Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. Aliment.Pharmacol.Ther. 1994;8(1):127-130. View abstract.
Berger, M. M., Baines, M., Raffoul, W., Benathan, M., Chiolero, R. L., Reeves, C., Revelly, J. P., Cayeux, M. C., Senechaud, I., and Shenkin, A. Trace element supplementation after major burns modulates antioxidant status and clinical course by way of increased tissue trace element concentrations. Am J Clin Nutr 2007;85(5):1293-1300. View abstract.
Bhan, G., Bhandari, N., Taneja, S., Mazumder, S., and Bahl, R. The effect of maternal education on gender bias in care-seeking for common childhood illnesses. Soc Sci Med 2005;60(4):715-724. View abstract.
Bhandari, N., Bahl, R., Taneja, S., Strand, T., Molbak, K., Ulvik, R. J., Sommerfelt, H., and Bhan, M. K. Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children. Pediatrics 2002;109(6):e86. View abstract.
Bhandari, N., Mazumder, S., Taneja, S., Dube, B., Agarwal, R. C., Mahalanabis, D., Fontaine, O., Black, R. E., and Bhan, M. K. Effectiveness of zinc supplementation plus oral rehydration salts compared with oral rehydration salts alone as a treatment for acute diarrhea in a primary care setting: a cluster randomized trial. Pediatrics 2008;121(5):e1279-e1285. View abstract.
Bhatnagar, S., Bahl, R., Sharma, P. K., Kumar, G. T., Saxena, S. K., and Bhan, M. K. Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial. J Pediatr.Gastroenterol.Nutr 2004;38(1):34-40. View abstract.
Bhutta, Z. A., Nizami, S. Q., and Isani, Z. Zinc supplementation in malnourished children with persistent diarrhea in Pakistan. Pediatrics 1999;103(4):e42. View abstract.
Black, M. R., Medeiros, D. M., Brunett, E., and Welke, R. Zinc supplements and serum lipids in young adult white males. Am.J.Clin.Nutr. 1988;47(6):970-975. View abstract.
Bobat, R., Coovadia, H., Stephen, C., Naidoo, K. L., McKerrow, N., Black, R. E., and Moss, W. J. Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial. Lancet 11-26-2005;366(9500):1862-1867. View abstract.
Bogden, J. D., Bendich, A., Kemp, F. W., Bruening, K. S., Shurnick, J. H., Denny, T., Baker, H., and Louria, D. B. Daily micronutrient supplements enhance delayed-hypersensitivity skin test responses in older people. Am.J Clin Nutr. 1994;60(3):437-447. View abstract.
Bogden, J. D., Oleske, J. M., Lavenhar, M. A., Munves, E. M., Kemp, F. W., Bruening, K. S., Holding, K. J., Denny, T. N., Guarino, M. A., and Holland, B. K. Effects of one year of supplementation with zinc and other micronutrients on cellular immunity in the elderly. J.Am.Coll.Nutr. 1990;9(3):214-225. View abstract.
Bogden, J. D., Oleske, J. M., Lavenhar, M. A., Munves, E. M., Kemp, F. W., Bruening, K. S., Holding, K. J., Denny, T. N., Guarino, M. A., Krieger, L. M., and . Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months. Am.J.Clin.Nutr. 1988;48(3):655-663. View abstract.
Bogden, J. D., Thind, I. S., Louria, D. B., and Caterini, H. Maternal and cord blood metal concentrations and low birth weight--a case-control study. Am J Clin Nutr 1978;31(7):1181-1187. View abstract.
Bonham, M., O'Connor, J. M., McAnena, L. B., Walsh, P. M., Downes, C. S., Hannigan, B. M., and Strain, J. J. Zinc supplementation has no effect on lipoprotein metabolism, hemostasis, and putative indices of copper status in healthy men. Biol.Trace Elem.Res. 2003;93(1-3):75-86. View abstract.
Boran, P., Tokuc, G., Vagas, E., Oktem, S., and Gokduman, M. K. Impact of zinc supplementation in children with acute diarrhoea in Turkey. Arch.Dis.Child 2006;91(4):296-299. View abstract.
Bosch, F. and Jimenez, E. Post-marketing surveillance of zinc acexamate in peptic ulcer treatment. Clin Trials J 1990;27:301-312.
Bose, A., Coles, C. L., Gunavathi, John, H., Moses, P., Raghupathy, P., Kirubakaran, C., Black, R. E., Brooks, W. A., and Santosham, M. Efficacy of zinc in the treatment of severe pneumonia in hospitalized children <2 y old. Am J Clin Nutr 2006;83(5):1089-1096. View abstract.
Boukaiba, N., Flament, C., Acher, S., Chappuis, P., Piau, A., Fusselier, M., Dardenne, M., and Lemonnier, D. A physiological amount of zinc supplementation: effects on nutritional, lipid, and thymic status in an elderly population. Am.J Clin Nutr. 1993;57(4):566-572. View abstract.
Brandes, J. M., Lightman, A., Itskovitz, J., and Zinder, O. Zinc concentration in gravida's serum and amniotic fluid during normal pregnancy. Biol Neonate 1980;38(1-2):66-70. View abstract.
Brandrup, F., Menne, T., Agren, M. S., Stromberg, H. E., Holst, R., and Frisen, M. A randomized trial of two occlusive dressings in the treatment of leg ulcers. Acta Derm.Venereol 1990;70(3):231-235. View abstract.
Braunschweig, C. L., Sowers, M., Kovacevich, D. S., Hill, G. M., and August, D. A. Parenteral zinc supplementation in adult humans during the acute phase response increases the febrile response. J Nutr 1997;127(1):70-74. View abstract.
Breskin, M. W., Worthington-Roberts, B. S., Knopp, R. H., Brown, Z., Plovie, B., Mottet, N. K., and Mills, J. L. First trimester serum zinc concentrations in human pregnancy. Am J Clin Nutr 1983;38(6):943-953. View abstract.
Brewer, G. J. and Hill, G. M. Zinc as a treatment for Wilson's disease--an orphan among orphans. Prog.Clin Biol Res 1985;197:143-156. View abstract.
Brewer, G. J., Brewer, L. F., and Prasad, A. S. Suppression of irreversibly sickled erythrocytes by zinc therapy in sickle cell anemia. J Lab Clin Med 1977;90(3):549-554. View abstract.
Brewer, G. J., Dick, R. D., Johnson, V. D., Fink, J. K., Kluin, K. J., and Daniels, S. Treatment of Wilson's disease with zinc XVI: treatment during the pediatric years. J.Lab Clin.Med. 2001;137(3):191-198. View abstract.
Brewer, G. J., Dick, R. D., Yuzbasiyan-Gurkan, V., Johnson, V., and Wang, Y. Treatment of Wilson's disease with zinc. XIII: Therapy with zinc in presymptomatic patients from the time of diagnosis. J Lab Clin Med 1994;123(6):849-858. View abstract.
Brewer, G. J., Hill, G. M., Dick, R. D., Nostrant, T. T., Sams, J. S., Wells, J. J., and Prasad, A. S. Treatment of Wilson's disease with zinc: III. Prevention of reaccumulation of hepatic copper. J Lab Clin Med. 1987;109(5):526-531. View abstract.
Brewer, G. J., Hill, G. M., Prasad, A. S., Cossack, Z. T., and Rabbani, P. Oral zinc therapy for Wilson's disease. Ann.Intern.Med 1983;99(3):314-319. View abstract.
Brewer, G. J., Johnson, V., Dick, R. D., Kluin, K. J., Fink, J. K., and Brunberg, J. A. Treatment of Wilson disease with ammonium tetrathiomolybdate. II. Initial therapy in 33 neurologically affected patients and follow-up with zinc therapy. Arch Neurol. 1996;53(10):1017-1025. View abstract.
Brewer, G. J., Yuzbasiyan-Gurkan, V., and Johnson, V. Treatment of Wilson's disease with zinc. IX: Response of serum lipids. J Lab Clin Med 1991;118(5):466-470. View abstract.
Brewer, G. J., Yuzbasiyan-Gurkan, V., and Young, A. B. Treatment of Wilson's disease. Semin Neurol. 1987;7(2):209-220. View abstract.
Brewer, G. J., Yuzbasiyan-Gurkan, V., Lee, D. Y., and Appelman, H. Treatment of Wilson's disease with zinc. VI. Initial treatment studies. J Lab Clin Med 1989;114(6):633-638. View abstract.
Brignola, C., Belloli, C., De Simone, G., Evangelisti, A., Parente, R., Mancini, R., Iannone, P., Mocheggiani, E., Fabris, N., Morini, M. C., and . Zinc supplementation restores plasma concentrations of zinc and thymulin in patients with Crohn's disease. Aliment.Pharmacol.Ther. 1993;7(3):275-280. View abstract.
Brocks, A., Reid, H., and Glazer, G. Acute intravenous zinc poisoning. Br.Med J 5-28-1977;1(6073):1390-1391. View abstract.
Brody, I. Treatment of recurrent furunculosis with oral zinc. Lancet 12-24-1977;2(8052-8053):1358. View abstract.
Brooks, W. A., Santosham, M., Naheed, A., Goswami, D., Wahed, M. A., Diener-West, M., Faruque, A. S., and Black, R. E. Effect of weekly zinc supplements on incidence of pneumonia and diarrhoea in children younger than 2 years in an urban, low-income population in Bangladesh: randomised controlled trial. Lancet 9-17-2005;366(9490):999-1004. View abstract.
Brooks, W. A., Santosham, M., Roy, S. K., Faruque, A. S., Wahed, M. A., Nahar, K., Khan, A. I., Khan, A. F., Fuchs, G. J., and Black, R. E. Efficacy of zinc in young infants with acute watery diarrhea. Am J Clin Nutr 2005;82(3):605-610. View abstract.
Brown, K. H., Peerson, J. M., Baker, S. K., and Hess, S. Y. Preventive zinc supplementation among infants, preschoolers, and older prepubertal children. Food Nutr.Bull. 2009;30(1 Suppl):S12-S40. View abstract.
Bucci, I., Napolitano, G., Giuliani, C., Lio, S., Minnucci, A., Di Giacomo, F., Calabrese, G., Sabatino, G., Palka, G., and Monaco, F. Zinc sulfate supplementation improves thyroid function in hypozincemic Down children. Biol.Trace Elem.Res. 1999;67(3):257-268. View abstract.
Bucci, I., Napolitano, G., Giuliani, C., Lio, S., Minnucci, A., Monaco, F., Di, Giacomo F., Calabrese, G., Palka, G., and Sabatino, G. Concerns about using Zn supplementation in Down's syndrome (DS) children. Biol.Trace Elem.Res 2001;82(1-3):273-275. View abstract.
Cameron, J., Hoffman, D., Wilson, J., and Cherry, G. Comparison of two peri-wound skin protectants in venous leg ulcers: a randomised controlled trial. J Wound Care 2005;14(5):233-236. View abstract.
Campos, D., Jr., Veras Neto, M. C., Silva, Filho, V, Leite, M. F., Holanda, M. B., and Cunha, N. F. [Zinc supplementation may recover taste for salt meals]. J.Pediatr.(Rio J.) 2004;80(1):55-59. View abstract.
Carcamo, C., Hooton, T., Weiss, N. S., Gilman, R., Wener, M. H., Chavez, V., Meneses, R., Echevarria, J., Vidal, M., and Holmes, K. K. Randomized controlled trial of zinc supplementation for persistent diarrhea in adults with HIV-1 infection. J Acquir.Immune.Defic.Syndr. 10-1-2006;43(2):197-201. View abstract.
Carr, R. R. and Nahata, M. C. Complementary and alternative medicine for upper-respiratory-tract infection in children. Am J Health Syst.Pharm 1-1-2006;63(1):33-39. View abstract.
Carruthers, R. Oral zinc sulphate in leg ulcers. Lancet 6-21-1969;1(7608):1264. View abstract.
Carter, J. P., Grivetti, L. E., Davis, J. T., Nasiff, S., Mansour, A., Mousa, W. A., Atta, A. E., Patwardhan, V. N., Abdel, Moneim M., Abdou, I. A., and Darby, W. J. Growth and sexual development of adolescent Egyptian village boys. Effects of zinc, iron, and placebo supplementation. Am J Clin Nutr 1969;22(1):59-78. View abstract.
Castellarnau, C., Martin, M., Marcos, A., Casaroli-Marano, R., Reina, M., and Vilaro, S. The activating function of bioactive dressing with ionic charge on human fibroblasts [Spanish]. Metas Enferm 2005;8(7):50-54.
Castilla-Higuero, L., Romero-Gomez, M., Suarez, E., and Castro, M. Acute hepatitis after starting zinc therapy in a patient with presymptomatic Wilson's disease. Hepatology 2000;32(4 Pt 1):877. View abstract.
Castillo-Duran, C., Marin, V. B., Alcazar, L. S., Iturralde, H., and Ruz, M. Controlled trial of zinc supplementation in Chilean pregnant adolescents. Nutr Res 2001;21:715-724.
Castillo-Duran, C., Rodriguez, A., Venegas, G., Alvarez, P., and Icaza, G. Zinc supplementation and growth of infants born small for gestational age. J.Pediatr. 1995;127(2):206-211. View abstract.
Caulfield, L. E., Zavaleta, N., and Figueroa, A. Adding zinc to prenatal iron and folate supplements improves maternal and neonatal zinc status in a Peruvian population. Am J Clin Nutr 1999;69(6):1257-1263. View abstract.
Caulfield, L. E., Zavaleta, N., Figueroa, A., and Leon, Z. Maternal zinc supplementation does not affect size at birth or pregnancy duration in Peru. J Nutr 1999;129(8):1563-1568. View abstract.
Cereda, E., Gini, A., Pedrolli, C., and Vanotti, A. Disease-specific, versus standard, nutritional support for the treatment of pressure ulcers in institutionalized older adults: a randomized controlled trial. J Am Geriatr.Soc 2009;57(8):1395-1402. View abstract.
Chandyo, R. K., Shrestha, P. S., Valentiner-Branth, P., Mathisen, M., Basnet, S., Ulak, M., Adhikari, R. K., Sommerfelt, H., and Strand, T. A. Two weeks of zinc administration to Nepalese children with pneumonia does not reduce the incidence of pneumonia or diarrhea during the next six months. J Nutr 2010;140(9):1677-1682. View abstract.
Chang, A. B., Torzillo, P. J., Boyce, N. C., White, A. V., Stewart, P. M., Wheaton, G. R., Purdie, D. M., Wakerman, J., and Valery, P. C. Zinc and vitamin A supplementation in Indigenous Australian children hospitalised with lower respiratory tract infection: a randomised controlled trial. Med J Aust 2-6-2006;184(3):107-112. View abstract.
Cherry, F. F., Sandstead, H. H., Rojas, P., Johnson, L. K., Batson, H. K., and Wang, X. B. Adolescent pregnancy: associations among body weight, zinc nutriture, and pregnancy outcome. Am.J.Clin.Nutr. 1989;50(5):945-954. View abstract.
Chevalier, C. A., Liepa, G., Murphy, M. D., Suneson, J., Vanbeber, A. D., Gorman, M. A., and Cochran, C. The effects of zinc supplementation on serum zinc and cholesterol concentrations in hemodialysis patients. J Ren Nutr 2002;12(3):183-189. View abstract.
Chhagan, M. K., Van den Broeck, J., Luabeya, K. K., Mpontshane, N., Tucker, K. L., and Bennish, M. L. Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa. Eur.J Clin Nutr 2009;63(7):850-857. View abstract.
Cho, E., Stampfer, M. J., Seddon, J. M., Hung, S., Spiegelman, D., Rimm, E. B., Willett, W. C., and Hankinson, S. E. Prospective study of zinc intake and the risk of age-related macular degeneration. Ann Epidemiol. 2001;11(5):328-336. View abstract.
Christian, P. Micronutrients, birth weight, and survival. Annu.Rev Nutr 8-21-2010;30:83-104. View abstract.
Christian, P., Khatry, S. K., Katz, J., Pradhan, E. K., LeClerq, S. C., Shrestha, S. R., Adhikari, R. K., Sommer, A., and West, K. P., Jr. Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomised community trial. BMJ 3-15-2003;326(7389):571. View abstract.
Christian, P., Stewart, C. P., LeClerq, S. C., Wu, L., Katz, J., West, K. P., Jr., and Khatry, S. K. Antenatal and postnatal iron supplementation and childhood mortality in rural Nepal: a prospective follow-up in a randomized, controlled community trial. Am J Epidemiol. 11-1-2009;170(9):1127-1136. View abstract.
Chung, C. S., Stookey, J., Dare, D., Welch, R., Nguyen, T. Q., Roehl, R., Peerson, J. M., King, J. C., and Brown, K. H. Current dietary zinc intake has a greater effect on fractional zinc absorption than does longer term zinc consumption in healthy adult men. Am J Clin Nutr 2008;87(5):1224-1229. View abstract.
Clayton, R. J. Double-blind trial of oral zinc sulphate in patients with leg ulcers. Br.J Clin Pract 1972;26(8):368-370. View abstract.
Cochran, R. J., Tucker, S. B., and Flannigan, S. A. Topical zinc therapy for acne vulgaris. Int.J Dermatol. 1985;24(3):188-190. View abstract.
Cohen, C. Zinc sulphate and bedsores. Br.Med J 6-1-1968;2(604):561. View abstract.
Coles, C. L., Bose, A., Moses, P. D., Mathew, L., Agarwal, I., Mammen, T., and Santosham, M. Infectious etiology modifies the treatment effect of zinc in severe pneumonia. Am J Clin Nutr 2007;86(2):397-403. View abstract.
Coles, C. L., Sherchand, J. B., Khatry, S. K., Katz, J., LeClerq, S. C., Mullany, L. C., and Tielsch, J. M. Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural Nepal. J Nutr 2008;138(12):2462-2467. View abstract.
Collipp, P. J. Effect of oral zinc supplements on diaper rash in normal infants. J Med Assoc.Ga 1989;78(9):621-623. View abstract.
Cope, E. C. and Levenson, C. W. Role of zinc in the development and treatment of mood disorders. Curr Opin.Clin Nutr.Metab Care 2010;13(6):685-689. View abstract.
Cope, E. C., Morris, D. R., and Levenson, C. W. Improving treatments and outcomes: an emerging role for zinc in traumatic brain injury. Nutr.Rev. 2012;70(7):410-413. View abstract.
Crouse, S. F., Hooper, P. L., Atterbom, H. A., and Papenfuss, R. L. Zinc ingestion and lipoprotein values in sedentary and endurance-trained men. JAMA 8-10-1984;252(6):785-787. View abstract.
Cuevas, F. R., Mendez, A. A. V., and Andrade, I. C. Zinc hyaluronate effects on ulcers in diabetic patients [Spanish]. Gerokomos 2007;18(2):91-101.
Cunliffe, W. J. Unacceptable side-effects of oral zinc sulphate in the treatment of acne vulgaris. Br.J Dermatol. 1979;101(3):363. View abstract.
Czerwinski, A. W., Clark, M. L., Serafetinides, E. A., Perrier, C., and Huber, W. Safety and efficacy of zinc sulfate in geriatric patients. Clin Pharmacol.Ther. 1974;15(4):436-441. View abstract.
Czlonkowska, A., Gajda, J., and Rodo, M. Effects of long-term treatment in Wilson's disease with D-penicillamine and zinc sulphate. J.Neurol. 1996;243(3):269-273. View abstract.
da Costa, Mdo D., Spitz, M., Bacheschi, L. A., Leite, C. C., Lucato, L. T., and Barbosa, E. R. Wilson's disease: two treatment modalities. Correlations to pretreatment and posttreatment brain MRI. Neuroradiology 2009;51(10):627-633. View abstract.
Dahl, H., Norskov, K., Peitersen, E., and Hilden, J. Zinc therapy of acetazolamide-induced side-effects. Acta Ophthalmol.(Copenh) 1984;62(5):739-745. View abstract.
Dalgic, N., Sancar, M., Bayraktar, B., Pullu, M., and Hasim, O. Probiotic, zinc and lactose-free formula in children with rotavirus diarrhea: are they effective? Pediatr.Int 2011;53(5):677-682. View abstract.
Danesh, A., Janghorbani, M., and Mohammadi, B. Effects of zinc supplementation during pregnancy on pregnancy outcome in women with history of preterm delivery: a double-blind randomized, placebo-controlled trial. J Matern.Fetal Neonatal Med 2010;23(5):403-408. View abstract.
Darmon, N., Briend, A., and Desjeux, J. F. Zinc in the treatment of diarrhea. J.Pediatr.Gastroenterol.Nutr. 1997;25(3):363-365. View abstract.
Das, R. R., Singh, M., and Shafiq, N. Short-term therapeutic role of zinc in children < 5 years of age hospitalised for severe acute lower respiratory tract infection. Paediatr.Respir.Rev. 2012;13(3):184-191. View abstract.
David, T. J., Wells, F. E., Sharpe, T. C., and Gibbs, A. C. Low serum zinc in children with atopic eczema. Br.J Dermatol 1984;111(5):597-601. View abstract.
DeCook, C. A. and Hirsch, A. R. Anosmia due to inhalational zinc: a case report (abstract). Chem Senses 2000;25:659.
Dekker, L. H., Fijnvandraat, K., Brabin, B. J., and van Hensbroek, M. B. Micronutrients and sickle cell disease, effects on growth, infection and vaso-occlusive crisis: a systematic review. Pediatr.Blood Cancer 2012;59(2):211-215. View abstract.
Demetree, J. W., Safer, L. F., and Artis, W. M. The effect of zinc on the sebum secretion rate. Acta Derm.Venereol. 1980;60(2):166-169. View abstract.
Deng, C., Zheng, B., and She, S. [Clinical study of zinc for the treatment of chronic bacterial prostatitis]. Zhonghua Nan.Ke.Xue. 2004;10(5):368-370. View abstract.
Desneves, K. J., Todorovic, B. E., Cassar, A., and Crowe, T. C. Treatment with supplementary arginine, vitamin C and zinc in patients with pressure ulcers: a randomised controlled trial. Clin.Nutr. 2005;24(6):979-987. View abstract.
Dijkhuizen, M. A. and Wieringa, F. T. Vitamin A, iron and zinc deficiency in Indonesia: micronutrient interactions and effects of supplementation [thesis]. 2001;
Dimitropoulou, P., Nayee, S., Liu, J. F., Demetriou, L., van, Tongeren M., Hepworth, S. J., and Muir, K. R. Dietary zinc intake and brain cancer in adults: a case-control study. Br J Nutr 2008;99(3):667-673. View abstract.
Dinsmore, W. W., McMaster, D., and Alderdice, J. T. Points:Zinc state in anorexia nervosa. Br Med J (Clin Res Ed) 11-29-1986;293(6559):1441.
Disilvestro, R. A. Zinc in relation to diabetes and oxidative disease. J Nutr. 2000;130(5S Suppl):1509S-1511S. View abstract.
Doherty, C. P., Crofton, P. M., Sarkar, M. A., Shakur, M. S., Wade, J. C., Kelnar, C. J., Elmlinger, M. W., Ranke, M. B., and Cutting, W. A. Malnutrition, zinc supplementation and catch-up growth: changes in insulin-like growth factor I, its binding proteins, bone formation and collagen turnover. Clin.Endocrinol.(Oxf) 2002;57(3):391-399. View abstract.
Doherty, C. P., Sarkar, M. A., Shakur, M. S., Ling, S. C., Elton, R. A., and Cutting, W. A. Zinc and rehabilitation from severe protein-energy malnutrition: higher-dose regimens are associated with increased mortality. Am.J.Clin.Nutr. 1998;68(3):742-748. View abstract.
Dreno, B., Moyse, D., Alirezai, M., Amblard, P., Auffret, N., Beylot, C., Bodokh, I., Chivot, M., Daniel, F., Humbert, P., Meynadier, J., and Poli, F. Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris. Dermatology 2001;203(2):135-140. View abstract.
Duchateau, J., Delepesse, G., Vrijens, R., and Collet, H. Beneficial effects of oral zinc supplementation on the immune response of old people. Am.J.Med. 1981;70(5):1001-1004. View abstract.
Dunlop, A. L., Kramer, M. R., Hogue, C. J., Menon, R., and Ramakrishan, U. Racial disparities in preterm birth: an overview of the potential role of nutrient deficiencies. Acta Obstet.Gynecol.Scand. 2011;90(12):1332-1341. View abstract.
Dutta, P., Mitra, U., Datta, A., Niyogi, S. K., Dutta, S., Manna, B., Basak, M., Mahapatra, T. S., and Bhattacharya, S. K. Impact of zinc supplementation in malnourished children with acute watery diarrhoea. J Trop.Pediatr. 2000;46(5):259-263. View abstract.
Dutta, P., Mitra, U., Dutta, S., Naik, T. N., Rajendran, K., and Chatterjee, M. K. Zinc, vitamin A, and micronutrient supplementation in children with diarrhea: a randomized controlled clinical trial of combination therapy versus monotherapy. J Pediatr. 2011;159(4):633-637. View abstract.
Eby, G. A. and Halcomb, W. W. Ineffectiveness of zinc gluconate nasal spray and zinc orotate lozenges in common-cold treatment: a double-blind, placebo-controlled clinical trial. Altern.Ther.Health Med 2006;12(1):34-38. View abstract.
Eggert, J. V., Siegler, R. L., and Edomkesmalee, E. Zinc supplementation in chronic renal failure. Int.J.Pediatr.Nephrol. 1982;3(1):21-24. View abstract.
Ellis, A. A., Winch, P., Daou, Z., Gilroy, K. E., and Swedberg, E. Home management of childhood diarrhoea in southern Mali--implications for the introduction of zinc treatment. Soc Sci Med 2007;64(3):701-712. View abstract.
Enta, T. Peridigital dermatitis in children. Int J Dermatol. 1980;19(7):390-391. View abstract.
Ertekin, M. V., Koc, M., Karslioglu, I., and Sezen, O. Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study. Int.J.Radiat.Oncol.Biol.Phys. 1-1-2004;58(1):167-174. View abstract.
Esmaeli, B., Burnstine, M. A., Martonyi, C. L., Sugar, A., Johnson, V., and Brewer, G. J. Regression of Kayser-Fleischer rings during oral zinc therapy: correlation with systemic manifestations of Wilson's disease. Cornea 1996;15(6):582-588. View abstract.
Evans, J. R. and Henshaw, K. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane.Database.Syst.Rev. 2008;(1):CD000253. View abstract.
Evans, J. R. and Lawrenson, J. G. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane.Database.Syst.Rev. 2012;6:CD000253. View abstract.
Evans, J. R. and Lawrenson, J. G. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane.Database.Syst.Rev. 2012;11:CD000254. View abstract.
Evans, J. R. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane.Database.Syst.Rev 2006;(2):CD000254. View abstract.
Faber, M., Kvalsvig, J. D., Lombard, C. J., and Benade, A. J. Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants. Am J Clin Nutr 2005;82(5):1032-1039. View abstract.
Faergemann, J. and Fredriksson, T. An open trial of the effect of a zinc pyrithione shampoo in tinea versicolor. Cutis 1980;25(6):667, 669. View abstract.
Fahim, M. S. and Brawner, T. A. Treatment of genital herpes simplex virus in male patients. Arch.Androl 1980;4(1):79-85. View abstract.
Fahim, M. S., Brawner, T. A., and Hall, D. G. New treatment for herpes simplex virus type 2 [ultrasound and zinc, urea and tannic acid ointment]. Part II: Female patients. J Med 1980;11(2-3):143-167. View abstract.
Fahim, M., Brawner, T., Millikan, L., Nickell, M., and Hall, D. New treatment for herpes simplex virus type 2 [ultrasound and zinc, urea, and tannic acid ointment]. Part I--Male patients. J Med 1978;9(3):245-264. View abstract.
Fairbrother, K. J., Kowolik, M. J., Curzon, M. E., Muller, I., McKeown, S., Hill, C. M., Hannigan, C., Bartizek, R. D., and White, D. J. The comparative clinical efficacy of pyrophosphate/triclosan, copolymer/triclosan and zinc citrate/triclosan dentifrices for the reduction of supragingival calculus formation. J.Clin.Dent. 1997;8(2 Spec No):62-66. View abstract.
Fajolu, I. B., Emokpae, A., Oduwole, A. O., Silva, B. O., Abidoye, R. O., and Renner, J. K. Zinc supplementation in children with acute diarrhoea. Nig.Q.J Hosp.Med. 2008;18(2):101-103. View abstract.
Farinati, F., Cardin, R., D'Inca, R., Naccarato, R., and Sturniolo, G. C. Zinc treatment prevents lipid peroxidation and increases glutathione availability in Wilson's disease. J.Lab Clin.Med. 2003;141(6):372-377. View abstract.
Farr, B. M. and Gwaltney, J. M., Jr. The problems of taste in placebo matching: an evaluation of zinc gluconate for the common cold. J Chronic.Dis. 1987;40(9):875-879. View abstract.
Farvid, M. S., Jalali, M., Siassi, F., and Hosseini, M. Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes. Diabetes Care 2005;28(10):2458-2464. View abstract.
Farvid, M. S., Jalali, M., Siassi, F., Saadat, N., and Hosseini, M. The impact of vitamins and/or mineral supplementation on blood pressure in type 2 diabetes. J Am Coll.Nutr 2004;23(3):272-279. View abstract.
Federico, A., Iodice, P., Federico, P., Del Rio, A., Mellone, M. C., Catalano, G., and Federico, P. Effects of selenium and zinc supplementation on nutritional status in patients with cancer of digestive tract. Eur J Clin Nutr 2001;55(4):293-297. View abstract.
Feillet-Coudray, C., Meunier, N., Bayle, D., Brandolini-Bunlon, M., Andriollo-Sanchez, M., O'Connor, J. M., Maiani, G., Roussel, A. M., Mazur, A., and Coudray, C. Effect of zinc supplementation on in vitro copper-induced oxidation of low-density lipoproteins in healthy French subjects aged 55-70 years: the Zenith Study. Br.J Nutr 2006;95(6):1134-1142. View abstract.
Festa, M. D., Anderson, H. L., Dowdy, R. P., and Ellersieck, M. R. Effect of zinc intake on copper excretion and retention in men. Am J Clin Nutr 1985;41(2):285-292. View abstract.
Fine, D. H., Furgang, D., Sinatra, K., Charles, C., McGuire, A., and Kumar, L. D. In vivo antimicrobial effectiveness of an essential oil-containing mouth rinse 12 h after a single use and 14 days' use. J Clin Periodontol. 2005;32(4):335-340. View abstract.
Finnerty, E. F. Topical zinc in the treatment of herpes simplex. Cutis 1986;37(2):130-131. View abstract.
Firooz, A., Khatami, A., Khamesipour, A., Nassiri-Kashani, M., Behnia, F., Nilforoushzadeh, M., Pazoki-Toroudi, H., and Dowlati, Y. Intralesional injection of 2% zinc sulfate solution in the treatment of acute old world cutaneous leishmaniasis: a randomized, double-blind, controlled clinical trial. J Drugs Dermatol 2005;4(1):73-79. View abstract.
Fischer Walker, C. L. and Black, R. E. Micronutrients and diarrheal disease. Clin Infect.Dis. 7-15-2007;45 Suppl 1:S73-S77. View abstract.
Fischer Walker, C. L., Baqui, A. H., Ahmed, S., Zaman, K., El, Arifeen S., Begum, N., Yunus, M., Black, R. E., and Caulfield, L. E. Low-dose weekly supplementation of iron and/or zinc does not affect growth among Bangladeshi infants. Eur.J Clin Nutr 2009;63(1):87-92. View abstract.
Fischer Walker, C. L., Bhutta, Z. A., Bhandari, N., Teka, T., Shahid, F., Taneja, S., and Black, R. E. Zinc supplementation for the treatment of diarrhea in infants in Pakistan, India and Ethiopia. J Pediatr.Gastroenterol.Nutr 2006;43(3):357-363. View abstract.
Fischer Walker, C. L., Black, R. E., and Baqui, A. H. Does age affect the response to zinc therapy for diarrhoea in Bangladeshi infants? J Health Popul.Nutr 2008;26(1):105-109. View abstract.
Fischman, S., Picozzi, A., Cancro, L., and Pader, M. Influence of a chlorhexidine and a zinc mouthrinse on gingivitis. J Periodontol. 1975;46(12):710-714. View abstract.
Fitzherbert, J. C. Genital herpes and zinc. Med J Aust. 5-5-1979;1(9):399. View abstract.
Fjellner, B. Drug-induced lupus erythematosus aggravated by oral zinc therapy. Acta Derm.Venereol. 1979;59(4):368-370. View abstract.
Flagothier, C., Pierard-Franchimont, C., and Pierard, G. E. [How I explore ... diaper dermatitis]. Rev.Med Liege 2004;59(2):106-109. View abstract.
Flament, M. F., Bissada, H., and Spettigue, W. Evidence-based pharmacotherapy of eating disorders. Int J Neuropsychopharmacol. 2012;15(2):189-207. View abstract.
Floersheim, G. L. and Lais, E. [Lack of effect of oral zinc sulfate on wound healing in leg ulcer]. Schweiz.Med Wochenschr. 7-26-1980;110(30):1138-1145. View abstract.
Folwaczny, C. [Role of zinc in treatment of acute diarrhea]. Z.Gastroenterol. 1996;34(4):260-262. View abstract.
Fontaine, O. Effect of zinc supplementation on clinical course of acute diarrhoea. J Health Popul.Nutr. 2001;19(4):339-346. View abstract.
Foster, M., Petocz, P., and Samman, S. Effects of zinc on plasma lipoprotein cholesterol concentrations in humans: a meta-analysis of randomised controlled trials. Atherosclerosis 2010;210(2):344-352. View abstract.
Franceschi, C., Chiricolo, M., Licastro, F., Zannotti, M., Masi, M., Mocchegiani, E., and Fabris, N. Oral zinc supplementation in Down's syndrome: restoration of thymic endocrine activity and of some immune defects. J Ment.Defic.Res 1988;32 ( Pt 3):169-181. View abstract.
Fraser, P. M., Doll, R., Langman, M. J., Misiewicz, J. J., and Shawdon, H. H. Clinical trial of a new carbenoxolone analogue (BX24), zinc sulphate, and vitamin A in the treatment of gastric ulcer. Gut 1972;13(6):459-463. View abstract.
Fredriksson, T. and Faergemann, J. Double-blind comparison of a zinc pyrithione shampoo and its shampoo base in the treatment of tinea versicolor. Cutis 1983;31(4):436-437. View abstract.
Freeland-Graves, J. H., Friedman, B. J., Han, W. H., Shorey, R. L., and Young, R. Effect of zinc supplementation on plasma high-density lipoprotein cholesterol and zinc. Am.J.Clin.Nutr. 1982;35(5):988-992. View abstract.
Friis, H., Ndhlovu, P., Mduluza, T., Kaondera, K., Sandstrom, B., Michaelsen, K. F., Vennervald, B. J., and Christensen, N. O. The impact of zinc supplementation on Schistosoma mansoni reinfection rate and intensities: a randomized, controlled trial among rural Zimbabwean schoolchildren. Eur.J Clin Nutr 1997;51(1):33-37. View abstract.
Fung, E. B., Ritchie, L. D., Woodhouse, L. R., Roehl, R., and King, J. C. Zinc absorption in women during pregnancy and lactation: a longitudinal study. Am J Clin Nutr 1997;66(1):80-88. View abstract.
Galli, F., Battistoni, A., Gambari, R., Pompella, A., Bragonzi, A., Pilolli, F., Iuliano, L., Piroddi, M., Dechecchi, M. C., and Cabrini, G. Oxidative stress and antioxidant therapy in cystic fibrosis. Biochim.Biophys.Acta 2012;1822(5):690-713. View abstract.
Gamble, R., Dunn, J., Dawson, A., Petersen, B., McLaughlin, L., Small, A., Kindle, S., and Dellavalle, R. P. Topical antimicrobial treatment of acne vulgaris: an evidence-based review. Am J Clin.Dermatol. 6-1-2012;13(3):141-152. View abstract.
Ganguly, A., Chakraborty, S., Datta, K., Hazra, A., Datta, S., and Chakraborty, J. A randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 months to 5 years. Indian J Pediatr. 2011;78(9):1085-1090. View abstract.
Gardner, J. M., Powell, C. A., Baker-Henningham, H., Walker, S. P., Cole, T. J., and Grantham-McGregor, S. M. Zinc supplementation and psychosocial stimulation: effects on the development of undernourished Jamaican children. Am J Clin Nutr 2005;82(2):399-405. View abstract.
Garg, H. K., Singhal, K. C., and Arshad, Z. A study of the effect of oral zinc supplementation during pregnancy on pregnancy outcome. Indian J.Physiol Pharmacol. 1993;37(4):276-284. View abstract.
Garner, S. E., Eady, A., Bennett, C., Newton, J. N., Thomas, K., and Popescu, C. M. Minocycline for acne vulgaris: efficacy and safety. Cochrane.Database.Syst.Rev. 2012;8:CD002086. View abstract.
Gatheru, Z., Kinoti, S., Alwar, J., and Mwita, M. Serum zinc levels in children with kwashiorkor aged one to three years at Kenyatta National Hospital and the effect of zinc supplementation during recovery. East Afr.Med J 1988;65(10):670-679. View abstract.
Gatto, L. M. and Samman, S. The effect of zinc supplementation on plasma lipids and low-density lipoprotein oxidation in males. Free Radic.Biol.Med 1995;19(4):517-521. View abstract.
Gebreselassie, S. G. and Gashe, F. E. A systematic review of effect of prenatal zinc supplementation on birthweight: meta-analysis of 17 randomized controlled trials. J Health Popul.Nutr. 2011;29(2):134-140. View abstract.
Ghosh, A., Fong, L. Y., Wan, C. W., Liang, S. T., Woo, J. S., and Wong, V. Zinc deficiency is not a cause for abortion, congenital abnormality and small-for-gestational age infant in Chinese women. Br.J Obstet.Gynaecol. 1985;92(9):886-891. View abstract.
Giroux, E., Schechter, P. J., and Schoun, J. Diminished albumin binding of zinc in serum of pregnant women. Clin Sci Mol.Med Suppl 1976;51(6):545-549. View abstract.
Golden, B. E. and Golden, M. H. Effect of zinc on lean tissue synthesis during recovery from malnutrition. Eur.J.Clin.Nutr. 1992;46(10):697-706. View abstract.
Golden, M. H., Golden, B. E., and Jackson, A. A. Skin breakdown in kwashiorkor responds to zinc. Lancet 6-7-1980;1(8180):1256. View abstract.
Golden, M. H., Harland, P. S., Golden, B. E., and Jackson, A. A. Zinc and immunocompetence in protein-energy malnutrition. Lancet 6-10-1978;1(8076):1226-1228. View abstract.
Golik, A., Cohen, N., Ramot, Y., Maor, J., Moses, R., Weissgarten, J., Leonov, Y., and Modai, D. Type II diabetes mellitus, congestive heart failure, and zinc metabolism. Biol.Trace Elem.Res 1993;39(2-3):171-175. View abstract.
Gouveia, J., Miguens, C., Sousa, L., Ferreira, C., Cruz, M., Machado, M., ilva, T., and Branco, C. Perilesional skin and leg ulcers: another side of the question (Portuguese). Nursing (Portugal) 2008;18(237):13-16.
Gracia, B., de Plata, C., Rueda, A., Mosquera, M., Suarez, M. F., and Pradilla, A. Effect of zinc supplementation on growth velocity of pre school children [Spanish]. Colombia Medica 2005;36(4):Suppl 3:31-40.
Graham, N. M., Sorensen, D., Odaka, N., Brookmeyer, R., Chan, D., Willett, W. C., Morris, J. S., and Saah, A. J. Relationship of serum copper and zinc levels to HIV-1 seropositivity and progression to AIDS. J Acquir.Immune.Defic.Syndr. 1991;4(10):976-980. View abstract.
Graham, R. M., James, M. P., and Bennett, S. Low concentration zinc sulphate solution in the management of recurrent herpes simplex infection. Br.J.Dermatol. 1985;112(1):123-124. View abstract.
Grases, F., Perello, J., Sanchis, P., Isern, B., Prieto, R. M., Costa-Bauza, A., Santiago, C., Ferragut, M. L., and Frontera, G. Anticalculus effect of a triclosan mouthwash containing phytate: a double-blind, randomized, three-period crossover trial. J Periodontal Res 2009;44(5):616-621. View abstract.
Grattan, B. J. and Freake, H. C. Zinc and cancer: implications for LIV-1 in breast cancer. Nutrients. 2012;4(7):648-675. View abstract.
Greaves, M. W. and Dawber, R. Zinc in psoriasis. Lancet 6-13-1970;1(7659):1295. View abstract.
Greaves, M. W. and Ive, F. A. Double-blind trial of zinc sulphate in the treatment of chronic venous leg ulceration. Br.J Dermatol. 1972;87(6):632-634. View abstract.
Greaves, M. W. and Skillen, A. W. Effects of long-continued ingestion of zinc sulphate in patients with venous leg ulceration. Lancet 10-31-1970;2(7679):889-891. View abstract.
Green, J. A., Lewin, S. R., Wightman, F., Lee, M., Ravindran, T. S., and Paton, N. I. A randomised controlled trial of oral zinc on the immune response to tuberculosis in HIV-infected patients. Int J Tuberc.Lung Dis. 2005;9(12):1378-1384. View abstract.
Greger, J. L. and Geissler, A. H. Effect of zinc supplementation on taste acuity of the aged. Am.J.Clin.Nutr. 1978;31(4):633-637. View abstract.
Gregorio, G. V., Dans, L. F., Cordero, C. P., and Panelo, C. A. Zinc supplementation reduced cost and duration of acute diarrhea in children. J Clin Epidemiol. 2007;60(6):560-566. View abstract.
Grimwood, K. and Forbes, D. A. Acute and persistent diarrhea. Pediatr Clin North Am 2009;56(6):1343-1361. View abstract.
Gueri, M., Van, Devanter S., Serjeant, B. E., and Serjeant, G. R. Oral zinc sulphate treatment of chronic non-sickle cell ulcers in Jamaica. West Indian Med J 1975;24(1):26-29. View abstract.
Gulani, A. and Sachdev, H. S. Zinc supplements for preventing otitis media. Cochrane.Database.Syst.Rev. 2012;4:CD006639. View abstract.
Gulani, A., Bhatnagar, S., and Sachdev, H. P. Neonatal zinc supplementation for prevention of mortality and morbidity in breastfed low birth weight infants: systematic review of randomized controlled trials. Indian Pediatr. 2011;48(2):111-117. View abstract.
Gunbay, S., Bicakci, N., Guneri, T., and Kirilmaz, L. The effect of zinc chloride dentifrices on plaque growth and oral zinc levels. Quintessence.Int. 1992;23(9):619-624. View abstract.
Gunsolley, J. C. A meta-analysis of six-month studies of antiplaque and antigingivitis agents. J Am Dent Assoc 2006;137(12):1649-1657. View abstract.
Gupta, D. N., Mondal, S. K., Ghosh, S., Rajendran, K., Sur, D., and Manna, B. Impact of zinc supplementation on diarrhoeal morbidity in rural children of West Bengal, India. Acta Paediatr. 2003;92(5):531-536. View abstract.
Gupta, R., Garg, V. K., Mathur, D. K., and Goyal, R. K. Oral zinc therapy in diabetic neuropathy. J Assoc.Physicians India 1998;46(11):939-942. View abstract.
Gupta, V. L. and Choubey, B. S. RBC survival, zinc deficiency, and efficacy of zinc therapy in sickle cell disease. Birth Defects Orig.Artic.Ser. 1987;23(5A):477-483. View abstract.
Gutierrez, Castrellon P., Polanco, Allue, I, and Salazar, Lindo E. [An evidence based Iberic-Latin American guideline for acute gastroenteritis management in infants and prescholars]. An.Pediatr.(Barc.) 2010;72(3):220. View abstract.
Haeger, K. and Lanner, E. Oral zinc sulphate and ischaemic leg ulcers. Vasa 1974;3(1):77-81. View abstract.
Haeger, K., Lanner, E., and Magnusson, P. O. Oral zinc sulphate in the treatment of venous leg ulcers. Vasa 1972;1(1):62-69. View abstract.
Hafeez, A., Mehmood, G., and Mazhar, F. Oral zinc supplementation in pregnant women and its effect on birth weight: a randomised controlled trial. Arch.Dis.Child Fetal Neonatal Ed 2005;90(2):F170-F171. View abstract.
Haider, B. A. and Bhutta, Z. A. The effect of therapeutic zinc supplementation among young children with selected infections: a review of the evidence. Food Nutr.Bull. 2009;30(1 Suppl):S41-S59. View abstract.
Haider, B. A., Lassi, Z. S., Ahmed, A., and Bhutta, Z. A. Zinc supplementation as an adjunct to antibiotics in the treatment of pneumonia in children 2 to 59 months of age. Cochrane.Database.Syst.Rev. 2011;(10):CD007368. View abstract.
Hakimi, M., Dibley, M., Surjono, A., and Nurdiati, D. Impact of vitamin A and zinc supplementation on puerperal sepsis: a randomized controlled trial in rural Indonesia. Nutrition and reproductive health in central Java, Indonesia; an epidemiological approach [PhD thesis]. 2001;
Hallbook, T. and Lanner, E. Serum-zinc and healing of venous leg ulcers. Lancet 10-14-1972;2(7781):780-782. View abstract.
Halyard, M. Y. Taste and smell alterations in cancer patients--real problems with few solutions. J Support.Oncol. 2009;7(2):68-69. View abstract.
Hamadani, J. D., Fuchs, G. J., Osendarp, S. J., Huda, S. N., and Grantham-McGregor, S. M. Zinc supplementation during pregnancy and effects on mental development and behaviour of infants: a follow-up study. Lancet 7-27-2002;360(9329):290-294. View abstract.
Hambidge, K. M., Abebe, Y., Gibson, R. S., Westcott, J. E., Miller, L. V., Lei, S., Stoecker, B. J., Arbide, I., Teshome, A., Bailey, K. B., and Krebs, N. F. Zinc absorption during late pregnancy in rural southern Ethiopia. Am J Clin Nutr 2006;84(5):1102-1106. View abstract.
Hambidge, K. M., Krebs, N. F., Jacobs, M. A., Favier, A., Guyette, L., and Ikle, D. N. Zinc nutritional status during pregnancy: a longitudinal study. Am.J.Clin.Nutr. 1983;37(3):429-442. View abstract.
Hambidge, K. M., Miller, L. V., Westcott, J. E., Sheng, X., and Krebs, N. F. Zinc bioavailability and homeostasis. Am J Clin Nutr 2010;91(5):1478S-1483S. View abstract.
Han, C. M. [Changes in body zinc and copper levels in severely burned patients and the effects of oral administration of ZnSO4 by a double-blind method]. Zhonghua Zheng.Xing.Shao Shang Wai Ke.Za Zhi. 1990;6(2):83-6, 155. View abstract.
Heckmann, S. M., Hujoel, P., Habiger, S., Friess, W., Wichmann, M., Heckmann, J. G., and Hummel, T. Zinc gluconate in the treatment of dysgeusia--a randomized clinical trial. J.Dent.Res. 2005;84(1):35-38. View abstract.
Heimall, L. M., Storey, B., Stellar, J. J., and Davis, K. F. Beginning at the bottom: evidence-based care of diaper dermatitis. MCN Am.J Matern.Child Nurs. 2012;37(1):10-16. View abstract.
Heinig, M. J., Brown, K. H., Lonnerdal, B., and Dewey, K. G. Zinc supplementation does not affect growth, morbidity, or motor development of US term breastfed infants at 4-10 mo of age. Am J Clin Nutr 2006;84(3):594-601. View abstract.
Hemalatha, P., Bhaskaram, P., and Khan, M. M. Role of zinc supplementation in the rehabilitation of severely malnourished children. Eur.J.Clin.Nutr. 1993;47(6):395-399. View abstract.
Hercberg, S., Bertrais, S., Czernichow, S., Noisette, N., Galan, P., Jaouen, A., Tichet, J., Briancon, S., Favier, A., Mennen, L., and Roussel, A. M. Alterations of the lipid profile after 7.5 years of low-dose antioxidant supplementation in the SU.VI.MAX Study. Lipids 2005;40(4):335-342. View abstract.
Heyland, D. K., Jones, N., Cvijanovich, N. Z., and Wong, H. Zinc supplementation in critically ill patients: a key pharmaconutrient? JPEN J Parenter.Enteral Nutr 2008;32(5):509-519. View abstract.
Heyman, H., Van De Looverbosch, D. E., Meijer, E. P., and Schols, J. M. Benefits of an oral nutritional supplement on pressure ulcer healing in long-term care residents. J Wound Care 2008;17(11):476-8, 480. View abstract.
Hidayat, A., Achadi, A., Sunoto, and Soedarmo, S. P. THe effect of zinc sulfate supplementation in children under three years of age with acute diarrhea in Indonesia. Med J Indonesia 1998;7:237-241.
Hill, G. M., Brewer, G. J., Juni, J. E., Prasad, A. S., and Dick, R. D. Treatment of Wilson's disease with zinc. II. Validation of oral 64copper with copper balance. Am J Med Sci 1986;292(6):344-349. View abstract.
Hill, G. M., Brewer, G. J., Prasad, A. S., Hydrick, C. R., and Hartmann, D. E. Treatment of Wilson's disease with zinc. I. Oral zinc therapy regimens. Hepatology 1987;7(3):522-528. View abstract.
Hinojosa, J., Prosper, M., Primo, J., and Moles, J. R. [The effect of a single nighttime dose of zinc acexamate (ZAC) on basal and pentagastrin-stimulated gastric secretion]. Rev Esp.Enferm.Dig. 1993;83(1):55-56. View abstract.
Hoggarth, A., Waring, M., Alexander, J., Greenwood, A., and Callaghan, T. A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants. Ostomy.Wound.Manage. 2005;51(12):30-42. View abstract.
Holtkamp, W., Brodersen, H. P., Thiery, J., Falkner, C., Bolzius, R., Larbig, D., and Reis, H. E. [Effect of zinc substitution on lymphocyte subsets and cellular immune function in hemodialysis patients]. Klin.Wochenschr. 6-18-1991;69(9):392-396. View abstract.
Holz, F. G., Wolfensberger, T. J., Piguet, B., Gross-Jendroska, M., Arden, G. B., and Bird, A. C. Oral zinc-therapy in age-related macular degeneration: a double-blind study (abstract). German Journal of Ophthalmology 1993;2:391.
Hong, Z. Y., Zhang, Y. W., Xu, J. D., Zhou, J. D., Gao, X. L., Liu, X. G., and Shi, Y. Y. Growth promoting effect of zinc supplementation in infants of high-risk pregnancies. Chin Med.J.(Engl.) 1992;105(10):844-848. View abstract.
Hoogenraad, T. U. and van den Hamer, C. J. 3 years of continuous oral zinc therapy in 4 patients with Wilson's disease. Acta Neurol.Scand. 1983;67(6):356-364. View abstract.
Hooper, P. L., Visconti, L., Garry, P. J., and Johnson, G. E. Zinc lowers high-density lipoprotein-cholesterol levels. JAMA 10-24-1980;244(17):1960-1961. View abstract.
Hovan, A. J., Williams, P. M., Stevenson-Moore, P., Wahlin, Y. B., Ohrn, K. E., Elting, L. S., Spijkervet, F. K., and Brennan, M. T. A systematic review of dysgeusia induced by cancer therapies. Support.Care Cancer 2010;18(8):1081-1087. View abstract.
Hu, D., Sreenivasan, P. K., Zhang, Y. P., and De, Vizio W. The effects of a zinc citrate dentifrice on bacteria found on oral surfaces. Oral Health Prev Dent. 2010;8(1):47-53. View abstract.
Humphreys, E. H., Smith, N. A., Azman, H., McLeod, D., and Rutherford, G. W. Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection. Cochrane Database Syst Rev 2010;(6):CD008563. View abstract.
Hunt, I. F., Murphy, N. J., Cleaver, A. E., Faraji, B., Swendseid, M. E., Browdy, B. L., Coulson, A. H., Clark, V. A., Settlage, R. H., and Smith, J. C., Jr. Zinc supplementation during pregnancy in low-income teenagers of Mexican descent: effects on selected blood constituents and on progress and outcome of pregnancy. Am.J.Clin.Nutr. 1985;42(5):815-828. View abstract.
Hunt, I. F., Murphy, N. J., Cleaver, A. E., Faraji, B., Swendseid, M. E., Coulson, A. H., Clark, V. A., Browdy, B. L., Cabalum, T., and Smith, J. C., Jr. Zinc supplementation during pregnancy: effects on selected blood constituents and on progress and outcome of pregnancy in low-income women of Mexican descent. Am J Clin Nutr 1984;40(3):508-521. View abstract.
Hunt, I. F., Murphy, N. J., Cleaver, A. E., Faraji, B., Swendseid, M. E., Coulson, A. H., Clark, V. A., Laine, N., Davis, C. A., and Smith, J. C., Jr. Zinc supplementation during pregnancy: zinc concentration of serum and hair from low-income women of Mexican descent. Am J Clin Nutr 1983;37(4):572-582. View abstract.
Hunt, I. F., Murphy, N. J., Gomez, J., and Smith, J. C., Jr. Dietary zinc intake of low-income pregnant women of Mexican descent. Am J Clin Nutr 1979;32(7):1511-1518. View abstract.
Hunt, J. R., Beiseigel, J. M., and Johnson, L. K. Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability. Am J Clin Nutr 2008;87(5):1336-1345. View abstract.
Hurley, M. N., Forrester, D. L., and Smyth, A. R. Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis. Cochrane.Database.Syst.Rev. 2010;(10):CD008037. View abstract.
Husain, S. L. Oral zinc sulphate in leg ulcers. Lancet 5-31-1969;1(7605):1069-1071. View abstract.
Hustead, V. A., Greger, J. L., and Gutcher, G. R. Zinc supplementation and plasma concentration of vitamin A in preterm infants. Am.J.Clin.Nutr. 1988;47(6):1017-1021. View abstract.
Iannotti, L. L., Zavaleta, N., Leon, Z., Huasquiche, C., Shankar, A. H., and Caulfield, L. E. Maternal zinc supplementation reduces diarrheal morbidity in peruvian infants. J Pediatr 2010;156(6):960-4, 964. View abstract.
Iannotti, L. L., Zavaleta, N., Leon, Z., Shankar, A. H., and Caulfield, L. E. Maternal zinc supplementation and growth in Peruvian infants. Am J Clin Nutr 2008;88(1):154-160. View abstract.
Imdad, A. and Bhutta, Z. A. Effect of preventive zinc supplementation on linear growth in children under 5 years of age in developing countries: a meta-analysis of studies for input to the lives saved tool. BMC.Public Health 2011;11 Suppl 3:S22. View abstract.
Imdad, A., Sadiq, K., and Bhutta, Z. A. Evidence-based prevention of childhood malnutrition. Curr.Opin.Clin.Nutr Metab Care 2011;14(3):276-285. View abstract.
Iraji, F., Vali, A., Asilian, A., Shahtalebi, M. A., and Momeni, A. Z. Comparison of intralesionally injected zinc sulfate with meglumine antimoniate in the treatment of acute cutaneous leishmaniasis. Dermatology 2004;209(1):46-49. View abstract.
Irlam, J. H., Visser, M. E., Rollins, N., and Siegfried, N. Micronutrient supplementation in children and adults with HIV infection. Cochrane.Database.Syst.Rev 2005;(4):CD003650. View abstract.
Irlam, J. H., Visser, M. M., Rollins, N. N., and Siegfried, N. Micronutrient supplementation in children and adults with HIV infection. Cochrane.Database.Syst.Rev. 2010;(12):CD003650. View abstract.
Isa, L., Lucchini, A., Lodi, S., and Giachetti, M. Blood zinc status and zinc treatment in human immunodeficiency virus-infected patients. Int J Clin Lab Res 1992;22(1):45-47. View abstract.
Ishikawa, T. Can zinc enhance response interferon therapy for patients with HCV-related liver disease? World J Gastroenterol. 7-7-2012;18(25):3196-3200. View abstract.
Jackson, J. L., Peterson, C., and Lesho, E. A meta-analysis of zinc salts lozenges and the common cold. Arch.Intern.Med 11-10-1997;157(20):2373-2376. View abstract.
Jafek, B. W., Linschoten, M. R., and Murrow, B. W. Anosmia after intranasal zinc gluconate use. Am J Rhinol. 2004;18(3):137-141. View abstract.
Jameson, S. Variations in maternal serum zinc during pregnancy and correlation to congenital malformations, dysmaturity, and abnormal parturition. Acta Med Scand.Suppl 1976;593:21-37. View abstract.
Job, C., Menkes, C. J., and Delbarre, F. Zinc sulfate in the treatment of rheumatoid arthritis. Arthritis Rheum. 1980;23(12):1408-1409. View abstract.
Jones, P. E. and Peters, T. J. Oral zinc supplements in non-responsive coeliac syndrome: effect on jejunal morphology, enterocyte production, and brush border disaccharidase activities. Gut 1981;22(3):194-198. View abstract.
Jones, R. Genital herpes and zinc. Med.J.Aust. 4-7-1979;1(7):286. View abstract.
Jonsson, B., Hauge, B., Larsen, M. F., and Hald, F. Zinc supplementation during pregnancy: a double blind randomised controlled trial. Acta Obstet.Gynecol.Scand 1996;75(8):725-729. View abstract.
Kajanachumpol, S., Srisurapanon, S., Supanit, I., Roongpisuthipong, C., and Apibal, S. Effect of zinc supplementation on zinc status, copper status and cellular immunity in elderly patients with diabetes mellitus. J Med Assoc Thai 1995;78(7):344-349. View abstract.
Kandhro, G. A., Kazi, T. G., Afridi, H. I., Kazi, N., Baig, J. A., Arain, M. B., Sirajuddin, Shah, A. Q., Sarfraz, R. A., Jamali, M. K., and Syed, N. Effect of zinc supplementation on the zinc level in serum and urine and their relation to thyroid hormone profile in male and female goitrous patients. Clin Nutr 2009;28(2):162-168. View abstract.
Kelemen, L. E., Cerhan, J. R., Lim, U., Davis, S., Cozen, W., Schenk, M., Colt, J., Hartge, P., and Ward, M. H. Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control study. Am J Clin Nutr 2006;83(6):1401-1410. View abstract.
Khaled, S., Brun, J. F., Cassanas, G., Bardet, L., and Orsetti, A. Effects of zinc supplementation on blood rheology during exercise. Clin.Hemorheol.Microcirc. 1999;20(1):1-10. View abstract.
Khanum, S., Alam, A. N., Anwar, I., Akbar, Ali M., and Mujibur, Rahaman M. Effect of zinc supplementation on the dietary intake and weight gain of Bangladeshi children recovering from protein-energy malnutrition. Eur.J.Clin.Nutr. 1988;42(8):709-714. View abstract.
Khattar, J. A., Musharrafieh, U. M., Tamim, H., and Hamadeh, G. N. Topical zinc oxide vs. salicylic acid-lactic acid combination in the treatment of warts. Int J Dermatol. 2007;46(4):427-430. View abstract.
Khatun, U. H. F. Impact of zinc and vitamin A supplementation in malnourished hospitalized children suffering from persistent diarrhoea. PhD thesis. The University of Dhaka, Dhaka, Bangladesh. 1998;
Khatun, U. H., Malek, M. A., Black, R. E., Sarkar, N. R., Wahed, M. A., Fuchs, G., and Roy, S. K. A randomized controlled clinical trial of zinc, vitamin A or both in undernourished children with persistent diarrhea in Bangladesh. Acta Paediatr. 2001;90(4):376-380. View abstract.
Kiilholma, P., Gronroos, M., Liukko, P., Pakarinen, P., Hyora, H., and Erkkola, R. Maternal serum copper and zinc concentrations in normal and small-for-date pregnancies. Gynecol.Obstet.Invest 1984;18(4):212-216. View abstract.
Kikuchi, M., Inagaki, T., and Hanaki, H. Effect of copper and zinc supplementation on peripheral leukocytes in neutropenia due to copper deficiency. Geriatri Gerontol Int 2005;5(4):259-266.
Kilic, M., Baltaci, A. K., and Gunay, M. Effect of zinc supplementation on hematological parameters in athletes. Biol.Trace Elem.Res. 2004;100(1):31-38. View abstract.
Koehler, K., Parr, M. K., Geyer, H., Mester, J., and Schanzer, W. Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement. Eur.J Clin Nutr 2009;63(1):65-70. View abstract.
Kordas, K., Stoltzfus, R. J., Lopez, P., Rico, J. A., and Rosado, J. L. Iron and zinc supplementation does not improve parent or teacher ratings of behavior in first grade Mexican children exposed to lead. J Pediatr 2005;147(5):632-639. View abstract.
Kremer, J. M. and Bigaouette, J. Nutrient intake of patients with rheumatoid arthritis is deficient in pyridoxine, zinc, copper, and magnesium. J Rheumatol. 1996;23(6):990-994. View abstract.
Kristensen, M. B., Hels, O., Morberg, C. M., Marving, J., Bugel, S., and Tetens, I. Total zinc absorption in young women, but not fractional zinc absorption, differs between vegetarian and meat-based diets with equal phytic acid content. Br.J Nutr 2006;95(5):963-967. View abstract.
Kurugol, Z., Akilli, M., Bayram, N., and Koturoglu, G. The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children. Acta Paediatr. 2006;95(10):1175-1181. View abstract.
Kurugol, Z., Bayram, N., and Atik, T. Effect of zinc sulfate on common cold in children: randomized, double blind study. Pediatr Int 2007;49(6):842-847. View abstract.
Kwok, C. S., Gibbs, S., Bennett, C., Holland, R., and Abbott, R. Topical treatments for cutaneous warts. Cochrane.Database.Syst.Rev. 2012;9:CD001781. View abstract.
Kynast, G. and Saling, E. Effect of oral zinc application during pregnancy. Gynecol Obstet.Invest 1986;21(3):117-123. View abstract.
Lagiou, P., Mucci, L., Tamimi, R., Kuper, H., Lagiou, A., Hsieh, C. C., and Trichopoulos, D. Micronutrient intake during pregnancy in relation to birth size. Eur.J Nutr 2005;44(1):52-59. View abstract.
Lai, J., Moxey, A., Nowak, G., Vashum, K., Bailey, K., and McEvoy, M. The efficacy of zinc supplementation in depression: systematic review of randomised controlled trials. J Affect.Disord. 2012;136(1-2):e31-e39. View abstract.
Lang, C. J., Rabas-Kolominsky, P., Engelhardt, A., Kobras, G., and Konig, H. J. Fatal deterioration of Wilson's disease after institution of oral zinc therapy. Arch Neurol. 1993;50(10):1007-1008. View abstract.
Langner, A., Chu, A., Goulden, V., and Ambroziak, M. A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide and adapalene in the treatment of mild to moderate facial acne vulgaris. Br.J Dermatol. 2008;158(1):122-129. View abstract.
Larson, C. P., Hoque, A. B., Larson, C. P., Khan, A. M., and Saha, U. R. Initiation of zinc treatment for acute childhood diarrhoea and risk for vomiting or regurgitation: a randomized, double-blind, placebo-controlled trial. J Health Popul.Nutr. 2005;23(4):311-319. View abstract.
Larson, C. P., Roy, S. K., Khan, A. I., Rahman, A. S., and Qadri, F. Zinc treatment to under-five children: applications to improve child survival and reduce burden of disease. J Health Popul.Nutr 2008;26(3):356-365. View abstract.
Lask, B., Fosson, A., Rolfe, U., and Thomas, S. Zinc deficiency and childhood-onset anorexia nervosa. J Clin Psychiatry 1993;54(2):63-66. View abstract.
Lassi, Z. S., Haider, B. A., and Bhutta, Z. A. Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months. Cochrane.Database.Syst.Rev. 2010;(12):CD005978. View abstract.
Lazzerini, M. and Ronfani, L. Oral zinc for treating diarrhoea in children. Cochrane.Database.Syst.Rev. 2008;(3):CD005436. View abstract.
Lazzerini, M. and Ronfani, L. Oral zinc for treating diarrhoea in children. Cochrane.Database.Syst.Rev. 2012;6:CD005436. View abstract.
Lee, D. H. and Jacobs, D. R., Jr. Interaction among heme iron, zinc, and supplemental vitamin C intake on the risk of lung cancer: Iowa Women's Health Study. Nutr Cancer 2005;52(2):130-137. View abstract.
Lee, S. S., Aprecio, R. M., Zhang, W., Arambula, M., Wilkins, K. B., Stephens, J. A., Kim, J. S., and Li, Y. Antiplaque/antigingivitis efficacy and safety of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel. Results of a 6-month clinical trial. Compend.Contin.Educ.Dent. 2008;29(5):302-4, 306, 308. View abstract.
Liang, J. Y., Liu, Y. Y., Zou, J., Franklin, R. B., Costello, L. C., and Feng, P. Inhibitory effect of zinc on human prostatic carcinoma cell growth. Prostate 8-1-1999;40(3):200-207. View abstract.
Licastro, F., Mocchegiani, E., Masi, M., and Fabris, N. Modulation of the neuroendocrine system and immune functions by zinc supplementation in children with Down's syndrome. J.Trace Elem.Electrolytes Health Dis. 1993;7(4):237-239. View abstract.
Licastro, F., Mocchegiani, E., Zannotti, M., Arena, G., Masi, M., and Fabris, N. Zinc affects the metabolism of thyroid hormones in children with Down's syndrome: normalization of thyroid stimulating hormone and of reversal triiodothyronine plasmic levels by dietary zinc supplementation. Int J Neurosci. 1992;65(1-4):259-268. View abstract.
Lim, J. H., Davis, G. E., Wang, Z., Li, V., Wu, Y., Rue, T. C., and Storm, D. R. Zicam-induced damage to mouse and human nasal tissue. PLoS.One. 2009;4(10):e7647. View abstract.
Lin, L. C., Que, J., Lin, K. L., Leung, H. W., Lu, C. L., and Chang, C. H. Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study. Int J Radiat.Oncol Biol Phys 2-1-2008;70(2):368-373. View abstract.
Lin, R. Y., Busher, J., Bogden, G. J., and Schwartz, R. A. Topical zinc sulfate augmentation of human delayed type skin test response. Acta Derm.Venereol. 1985;65(3):190-193. View abstract.
Lin, S. F., Wei, H., Maeder, D., Franklin, R. B., and Feng, P. Profiling of zinc-altered gene expression in human prostate normal vs. cancer cells: a time course study. J Nutr Biochem. 2009;20(12):1000-1012. View abstract.
Lin, Y. S., Lin, L. C., and Lin, S. W. Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis. Laryngoscope 2009;119(7):1348-1352. View abstract.
Lind, T., Lonnerdal, B., Stenlund, H., Gamayanti, I. L., Ismail, D., Seswandhana, R., and Persson, L. A. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development. Am.J.Clin.Nutr. 2004;80(3):729-736. View abstract.
Lockitch, G., Puterman, M., Godolphin, W., Sheps, S., Tingle, A. J., and Quigley, G. Infection and immunity in Down syndrome: a trial of long-term low oral doses of zinc. J.Pediatr. 1989;114(5):781-787. View abstract.
Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mexico. Am J Clin Nutr 2006;83(3):693-700. View abstract.
Long, K. Z., Rosado, J. L., Montoya, Y., de Lourdes, Solano M., Hertzmark, E., DuPont, H. L., and Santos, J. I. Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children. Pediatrics 2007;120(4):e846-e855. View abstract.
Lopez-Garcia, D. R., Gomez-Flores, M., Arce-Mendoza, A. Y., Fuente-Garcia, A., and Ocampo-Candiani, J. Oral zinc sulfate for unresponsive cutaneous viral warts: too good to be true? A double-blind, randomized, placebo-controlled trial. Clin Exp.Dermatol. 2009;34(8):e984-e985. View abstract.
Lu, H., Cai, L., Mu, L. N., Lu, Q. Y., Zhao, J., Cui, Y., Sul, J. H., Zhou, X. F., Ding, B. G., Elashoff, R. M., Marshall, J., Yu, S. Z., Jiang, Q. W., and Zhang, Z. F. Dietary mineral and trace element intake and squamous cell carcinoma of the esophagus in a Chinese population. Nutr Cancer 2006;55(1):63-70. View abstract.
Luabeya, K. K., Mpontshane, N., Mackay, M., Ward, H., Elson, I., Chhagan, M., Tomkins, A., Van den Broeck, J., and Bennish, M. L. Zinc or multiple micronutrient supplementation to reduce diarrhea and respiratory disease in South African children: a randomized controlled trial. PLoS.One. 2007;2(6):e541. View abstract.
Lukacik, M., Thomas, R. L., and Aranda, J. V. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. Pediatrics 2008;121(2):326-336. View abstract.
Madureira, G., Bloise, W., Mendonca, B. B., and Brandao-Neto, J. Effect of acute and chronic oral zinc administration in hyperprolactinemic patients. Met.Based Drugs 1999;6(3):159-162. View abstract.
Mahajan, S. K., Prasad, A. S., Lambujon, J., Abbasi, A. A., Briggs, W. A., and McDonald, F. D. Improvement of uremic hypogeusia by zinc. Trans.Am Soc Artif.Intern.Organs 1979;25:443-448. View abstract.
Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute lower respiratory infection. Am J Clin Nutr 2004;79(3):430-436. View abstract.
Mahomed, K. Zinc supplementation in pregnancy. Cochrane.Database.Syst.Rev 2000;(2):CD000230. View abstract.
Mahomed, K., Bhutta, Z., and Middleton, P. Zinc supplementation for improving pregnancy and infant outcome. Cochrane.Database.Syst.Rev. 2007;(2):CD000230. View abstract.
Mahomed, K., James, D. K., Golding, J., and McCabe, R. Zinc supplementation during pregnancy: a double blind randomised controlled trial. BMJ 9-30-1989;299(6703):826-830. View abstract.
Maia, P. A., Figueiredo, R. C., Anastacio, A. S., Porto da Silveira, C. L., and Donangelo, C. M. Zinc and copper metabolism in pregnancy and lactation of adolescent women. Nutrition 2007;23(3):248-253. View abstract.
Makonnen, B., Venter, A., and Joubert, G. A randomized controlled study of the impact of dietary zinc supplementation in the management of children with protein-energy malnutrition in Lesotho. I: Mortality and morbidity. J.Trop.Pediatr. 2003;49(6):340-352. View abstract.
Makonnen, B., Venter, A., and Joubert, G. A randomized controlled study of the impact of dietary zinc supplementation in the management of children with protein-energy malnutrition in Lesotho. II: Special investigations. J.Trop.Pediatr. 2003;49(6):353-360. View abstract.
Manger, M. S., McKenzie, J. E., Winichagoon, P., Gray, A., Chavasit, V., Pongcharoen, T., Gowachirapant, S., Ryan, B., Wasantwisut, E., and Gibson, R. S. A micronutrient-fortified seasoning powder reduces morbidity and improves short-term cognitive function, but has no effect on anthropometric measures in primary school children in northeast Thailand: a randomized controlled trial. Am J Clin Nutr 2008;87(6):1715-1722. View abstract.
Marcellini, F., Giuli, C., Papa, R., Gagliardi, C., Dedoussis, G., Monti, D., Jajte, J., Giacconi, R., Malavolta, M., and Mocchegiani, E. Zinc in elderly people: effects of zinc supplementation on psychological dimensions in dependence of IL-6 -174 polymorphism: a Zincage study. Rejuvenation.Res 2008;11(2):479-483. View abstract.
Marcellini, M., Di, Ciommo, V, Callea, F., Devito, R., Comparcola, D., Sartorelli, M. R., Carelli, G., and Nobili, V. Treatment of Wilson's disease with zinc from the time of diagnosis in pediatric patients: a single-hospital, 10-year follow-up study. J Lab Clin Med 2005;145(3):139-143. View abstract.
Marchesini, G., Bugianesi, E., Ronchi, M., Flamia, R., Thomaseth, K., and Pacini, G. Zinc supplementation improves glucose disposal in patients with cirrhosis. Metabolism 1998;47(7):792-798. View abstract.
Marks, R., Pearse, A. D., and Walker, A. P. The effects of a shampoo containing zinc pyrithione on the control of dandruff. Br.J.Dermatol. 1985;112(4):415-422. View abstract.
Mathe, G., Blazsek, I., Canon, C., Gil-Delgado, M., and Misset, J. L. From experimental to clinical attempts in immunorestoration with bestatin and zinc. Comp Immunol.Microbiol.Infect.Dis. 1986;9(2-3):241-252. View abstract.
Mathew, J. L. Zinc supplementation for prevention or treatment of childhood pneumonia: a systematic review of randomized controlled trials. Indian Pediatr. 2010;47(1):61-66. View abstract.
Mathew, J. L., Patwari, A. K., Gupta, P., Shah, D., Gera, T., Gogia, S., Mohan, P., Panda, R., and Menon, S. Acute respiratory infection and pneumonia in India: a systematic review of literature for advocacy and action: UNICEF-PHFI series on newborn and child health, India. Indian Pediatr. 2011;48(3):191-218. View abstract.
Mathur, N. K. and Bumb, R. A. Oral zinc in the trophic ulcers of leprosy. Int J Lepr.Other Mycobact.Dis 1983;51(3):410-411. View abstract.
Matson, A., Wright, M., Oliver, A., Woodrow, G., King, N., Dye, L., Blundell, J., Brownjohn, A., and Turney, J. Zinc supplementation at conventional doses does not improve the disturbance of taste perception in hemodialysis patients. J Ren Nutr 2003;13(3):224-228. View abstract.
Mattingly, P. C. and Mowat, A. G. Zinc sulphate in rheumatoid arthritis. Ann.Rheum.Dis. 1982;41(5):456-457. View abstract.
Maylor, E. A., Simpson, E. E., Secker, D. L., Meunier, N., Andriollo-Sanchez, M., Polito, A., Stewart-Knox, B., McConville, C., O'Connor, J. M., and Coudray, C. Effects of zinc supplementation on cognitive function in healthy middle-aged and older adults: the ZENITH study. Br.J Nutr 2006;96(4):752-760. View abstract.
Mazariegos, M., Hambidge, K. M., Westcott, J. E., Solomons, N. W., Raboy, V., Das, A., Goco, N., Kindem, M., Wright, L. L., and Krebs, N. F. Neither a zinc supplement nor phytate-reduced maize nor their combination enhance growth of 6- to 12-month-old Guatemalan infants. J Nutr 2010;140(5):1041-1048. View abstract.
McClain, C. J., Stuart, M. A., Vivian, B., McClain, M., Talwalker, R., Snelling, L., and Humphries, L. Zinc status before and after zinc supplementation of eating disorder patients. J.Am.Coll.Nutr. 1992;11(6):694-700. View abstract.
McElroy, B. H. and Miller, S. P. An open-label, single-center, phase IV clinical study of the effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) in reducing the duration and symptoms of the common cold in school-aged subjects. Am.J.Ther. 2003;10(5):324-329. View abstract.
Mda, S., van Raaij, J. M., Macintyre, U. E., de Villiers, F. P., and Kok, F. J. Improved appetite after multi-micronutrient supplementation for six months in HIV-infected South African children. Appetite 2010;54(1):150-155. View abstract.
Meadows, N. J., Ruse, W., Smith, M. F., Day, J., Keeling, P. W., Scopes, J. W., Thompson, R. P., and Bloxam, D. L. Zinc and small babies. Lancet 11-21-1981;2(8256):1135-1137. View abstract.
Meeks, Gardner J., Witter, M. M., and Ramdath, D. D. Zinc supplementation: effects on the growth and morbidity of undernourished Jamaican children. Eur.J Clin Nutr 1998;52(1):34-39. View abstract.
Mei, W., Dong, Z. M., Liao, B. L., and Xu, H. B. Study of immune function of cancer patients influenced by supplemental zinc or selenium-zinc combination. Biol.Trace Elem.Res. 1991;28(1):11-19. View abstract.
Mendez-Sanchez, N., Martinez, M., Gonzalez, V., Roldan-Valadez, E., Flores, M. A., and Uribe, M. Zinc sulfate inhibits the enterohepatic cycling of unconjugated bilirubin in subjects with Gilbert's syndrome. Ann.Hepatol. 2002;1(1):40-43. View abstract.
Menkes, C. J., Job, C., and Delbarre, F. [Treatment of rheumatoid arthritis by zinc sulfate per os]. Nouv.Presse Med. 3-4-1978;7(3):760. View abstract.
Menkes, C. J., Job, Ch, Buneaux, F., and Delbarre, F. [Treatment of rheumatoid arthritis with zinc sulfate. Results of a doubl-blind trial]. Rev.Rhum.Mal Osteoartic. 1981;48(3):223-227. View abstract.
Merchant, H. W., Gangarosa, L. P., Morse, P. K., Strain, W. H., and Baisden, C. R. Zinc sulfate as a preventive of recurrent aphthuos ulcers. J Dent.Res 1981;60A:6009.
Merialdi, M., Caulfield, L. E., Zavaleta, N., Figueroa, A., and Dipietro, J. A. Adding zinc to prenatal iron and folate tablets improves fetal neurobehavioral development. Am.J.Obstet.Gynecol. 1999;180(2 Pt 1):483-490. View abstract.
Merialdi, M., Caulfield, L. E., Zavaleta, N., Figueroa, A., Costigan, K. A., Dominici, F., and Dipietro, J. A. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth. Am.J.Clin.Nutr. 2004;79(5):826-830. View abstract.
Merialdi, M., Caulfield, L. E., Zavaleta, N., Figueroa, A., Dominici, F., and Dipietro, J. A. Randomized controlled trial of prenatal zinc supplementation and the development of fetal heart rate. Am.J.Obstet.Gynecol. 2004;190(4):1106-1112. View abstract.
Michaelsson, G. Oral zinc in acne. Acta Derm.Venereol.Suppl (Stockh) 1980;Suppl 89:87-93. View abstract.
Mocchegiani, E., Muzzioli, M., Gaetti, R., Veccia, S., Viticchi, C., and Scalise, G. Contribution of zinc to reduce CD4+ risk factor for 'severe' infection relapse in aging: parallelism with HIV. Int.J.Immunopharmacol. 1999;21(4):271-281. View abstract.
Moore, R. Bleeding gastric erosion after oral zinc sulphate. Br.Med J 3-25-1978;1(6115):754. View abstract.
Moran, J., Newcombe, R. G., Wright, P., Haywood, J., Marlow, I., and Addy, M. A study into the plaque-inhibitory activity of experimental toothpaste formulations containing antimicrobial agents. J Clin Periodontol. 2005;32(8):841-845. View abstract.
Morgan, A. A. Bleeding gastric erosion after oral zinc sulphate. Br.Med.J. 5-13-1978;1(6122):1283-1284. View abstract.
Mori, R., Ota, E., Middleton, P., Tobe-Gai, R., Mahomed, K., and Bhutta, Z. A. Zinc supplementation for improving pregnancy and infant outcome. Cochrane.Database.Syst.Rev. 2012;7:CD000230. View abstract.
Mozaffari-Khosravi, H., Shakiba, M., Eftekhari, M. H., and Vahidi, A. R. Effects of zinc supplementation on the physical growth of 2-5 years old children. Iranian J Endocrinol Metab 2008;10(4):417.
Mukherjee, M. D., Sandstead, H. H., Ratnaparkhi, M. V., Johnson, L. K., Milne, D. B., and Stelling, H. P. Maternal zinc, iron, folic acid, and protein nutriture and outcome of human pregnancy. Am J Clin Nutr 1984;40(3):496-507. View abstract.
Munguia, C., Paniagua, R., Avila-Diaz, M., Nava-Hernandez, J., Rodriguez, E., Ventura, Mde J., and Amato, D. [Effect of zinc supplements on the nutritional status of patients undergoing continuous ambulatory peritoneal dialysis]. Rev.Invest Clin 2003;55(5):519-527. View abstract.
Munoz, E. C., Rosado, J. L., Lopez, P., Furr, H. C., and Allen, L. H. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am.J.Clin.Nutr. 2000;71(3):789-794. View abstract.
Murphy, J. V. Intoxication following ingestion of elemental zinc. JAMA 6-22-1970;212(12):2119-2120. View abstract.
Myers, M. B. and Cherry, G. Zinc and the healing of chronic leg ulcers. Am.J.Surg. 1970;120(1):77-81. View abstract.
Nachnani, S. Reduction of oral malodor with Zinc containing Chewing gum(abstract). J Dent Res 1999;78
Nagalla, S. and Ballas, S. K. Drugs for preventing red blood cell dehydration in people with sickle cell disease. Cochrane.Database.Syst.Rev. 2010;(1):CD003426. View abstract.
Nagalla, S. and Ballas, S. K. Drugs for preventing red blood cell dehydration in people with sickle cell disease. Cochrane.Database.Syst.Rev. 2012;7:CD003426. View abstract.
Nahas, R. and Balla, A. Complementary and alternative medicine for prevention and treatment of the common cold. Can.Fam.Physician 2011;57(1):31-36. View abstract.
Naheed, A., Walker Fischer, C. L., Mondal, D., Ahmed, S., Arifeen, S. E., Yunus, M., Black, R. E., and Baqui, A. H. Zinc therapy for diarrhoea improves growth among Bangladeshi infants 6 to 11 months of age. J Pediatr.Gastroenterol.Nutr 2009;48(1):89-93. View abstract.
Neggers, Y. H., Cutter, G. R., Acton, R. T., Alvarez, J. O., Bonner, J. L., Goldenberg, R. L., Go, R. C., and Roseman, J. M. A positive association between maternal serum zinc concentration and birth weight. Am J Clin Nutr 1990;51(4):678-684. View abstract.
Netter, A., Hartoma, R., and Nahoul, K. Effect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm count. Arch Androl 1981;7(1):69-73. View abstract.
Newsome, D. A. A randomized, prospective, placebo-controlled clinical trial of a novel zinc-monocysteine compound in age-related macular degeneration. Curr Eye Res 2008;33(7):591-598. View abstract.
Nguyen, P. H., Grajeda, R., Melgar, P., Marcinkevage, J., DiGirolamo, A. M., Flores, R., and Martorell, R. Micronutrient supplementation may reduce symptoms of depression in Guatemalan women. Arch.Latinoam.Nutr. 2009;59(3):278-286. View abstract.
Nguyen, P., Grajeda, R., Melgar, P., Marcinkevage, J., Flores, R., and Martorell, R. Weekly may be as efficacious as daily folic acid supplementation in improving folate status and lowering serum homocysteine concentrations in Guatemalan women. J Nutr 2008;138(8):1491-1498. View abstract.
Ninh, N. X., Thissen, J. P., Collette, L., Gerard, G., Khoi, H. H., and Ketelslegers, J. M. Zinc supplementation increases growth and circulating insulin-like growth factor I (IGF-I) in growth-retarded Vietnamese children. Am.J.Clin.Nutr. 1996;63(4):514-519. View abstract.
Nowak, G., Siwek, M., Dudek, D., Zieba, A., and Pilc, A. Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study. Pol.J Pharmacol. 2003;55(6):1143-1147. View abstract.
Ochi, K., Ohashi, T., Kinoshita, H., Akagi, M., Kikuchi, H., Mitsui, M., Kaneko, T., and Kato, I. [The serum zinc level in patients with tinnitus and the effect of zinc treatment]. Nippon Jibiinkoka Gakkai Kaiho 1997;100(9):915-919. View abstract.
Ohrn, K. E., Wahlin, Y. B., and Sjoden, P. O. Oral status during radiotherapy and chemotherapy: a descriptive study of patient experiences and the occurrence of oral complications. Support.Care Cancer 2001;9(4):247-257. View abstract.
Omu, A. E., Al-Azemi, M. K., Kehinde, E. O., Anim, J. T., Oriowo, M. A., and Mathew, T. C. Indications of the mechanisms involved in improved sperm parameters by zinc therapy. Med.Princ.Pract. 2008;17(2):108-116. View abstract.
Opstelten, W., Neven, A. K., and Eekhof, J. Treatment and prevention of herpes labialis. Can.Fam.Physician 2008;54(12):1683-1687. View abstract.
Orbak, R., Cicek, Y., Tezel, A., and Dogru, Y. Effects of zinc treatment in patients with recurrent aphthous stomatitis. Dent.Mater.J. 2003;22(1):21-29. View abstract.
Osendarp, S. J., Santosham, M., Black, R. E., Wahed, M. A., van Raaij, J. M., and Fuchs, G. J. Effect of zinc supplementation between 1 and 6 mo of life on growth and morbidity of Bangladeshi infants in urban slums. Am J Clin Nutr 2002;76(6):1401-1408. View abstract.
Osendarp, S. J., van Raaij, J. M., Arifeen, S. E., Wahed, M., Baqui, A. H., and Fuchs, G. J. A randomized, placebo-controlled trial of the effect of zinc supplementation during pregnancy on pregnancy outcome in Bangladeshi urban poor. Am.J.Clin.Nutr. 2000;71(1):114-119. View abstract.
Osendarp, S. J., van Raaij, J. M., Darmstadt, G. L., Baqui, A. H., Hautvast, J. G., and Fuchs, G. J. Zinc supplementation during pregnancy and effects on growth and morbidity in low birthweight infants: a randomised placebo controlled trial. Lancet 4-7-2001;357(9262):1080-1085. View abstract.
Paaske, P. B., Pedersen, C. B., Kjems, G., and Sam, I. L. [Zinc therapy of tinnitus. A placebo-controlled study]. Ugeskr.Laeger 8-27-1990;152(35):2473-2475. View abstract.
Page, D. J., Gilbert, R. J., Bowen, W. H., and Stephen, K. W. Concentration of antimicrobial proteins in human saliva. The effect of long-term usage of a zinc-containing dentifrice on the protein composition of stimulated saliva from 198 children. Caries Res. 1990;24(3):216-219. View abstract.
Pandey, S. P., Bhattacharya, S. K., and Sundar, S. Zinc in rheumatoid arthritis. Indian J Med Res 1985;81:618-620. View abstract.
Paradiso, Galatioto G., Gravina, G. L., Angelozzi, G., Sacchetti, A., Innominato, P. F., Pace, G., Ranieri, G., and Vicentini, C. May antioxidant therapy improve sperm parameters of men with persistent oligospermia after retrograde embolization for varicocele? World J Urol. 2008;26(1):97-102. View abstract.
Partida-Hernandez, G., Arreola, F., Fenton, B., Cabeza, M., Roman-Ramos, R., and Revilla-Monsalve, M. C. Effect of zinc replacement on lipids and lipoproteins in type 2-diabetic patients. Biomed.Pharmacother. 2006;60(4):161-168. View abstract.
Patel, A. B., Dhande, L. A., and Rawat, M. S. Therapeutic evaluation of zinc and copper supplementation in acute diarrhea in children: double blind randomized trial. Indian Pediatr 2005;42(5):433-442. View abstract.
Patel, A. B., Mamtani, M., Badhoniya, N., and Kulkarni, H. What zinc supplementation does and does not achieve in diarrhea prevention: a systematic review and meta-analysis. BMC.Infect.Dis. 2011;11:122. View abstract.
Patel, A., Dibley, M. J., Mamtani, M., Badhoniya, N., and Kulkarni, H. Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. BMC.Med 2009;7:22. View abstract.
Patel, A., Mamtani, M., Dibley, M. J., Badhoniya, N., and Kulkarni, H. Therapeutic value of zinc supplementation in acute and persistent diarrhea: a systematic review. PLoS.One. 2010;5(4):e10386. View abstract.
Pathak, P., Kapil, U., Dwivedi, S. N., and Singh, R. Serum zinc levels amongst pregnant women in a rural block of Haryana state, India. Asia Pac.J Clin Nutr 2008;17(2):276-279. View abstract.
Patro, B., Szymanski, H., and Szajewska, H. Oral zinc for the treatment of acute gastroenteritis in Polish children: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2010;157(6):984-988. View abstract.
Payette, M. J., Whalen, J., and Grant-Kels, J. M. Nutrition and nonmelanoma skin cancers. Clin.Dermatol. 2010;28(6):650-662. View abstract.
Pelucchi, C., Grigoryan, L., Galeone, C., Esposito, S., Huovinen, P., Little, P., and Verheij, T. Guideline for the management of acute sore throat. Clin Microbiol.Infect. 2012;18 Suppl 1:1-28. View abstract.
Penny, M. E., Marin, R. M., Duran, A., Peerson, J. M., Lanata, C. F., Lonnerdal, B., Black, R. E., and Brown, K. H. Randomized controlled trial of the effect of daily supplementation with zinc or multiple micronutrients on the morbidity, growth, and micronutrient status of young Peruvian children. Am J Clin Nutr 2004;79(3):457-465. View abstract.
Peretz, A., Neve, J., Jeghers, O., and Pelen, F. Zinc distribution in blood components, inflammatory status, and clinical indexes of disease activity during zinc supplementation in inflammatory rheumatic diseases. Am.J.Clin.Nutr. 1993;57(5):690-694. View abstract.
Perez, Mota A., Perez, Munoz C., Casanova, Canovas A., and Perez, Fernandez E. [Acute and prophylactic treatment of peptic ulcer with zinc acexamate or cimetidine]. Med.Clin.(Barc.) 12-13-1986;87(20):839-842. View abstract.
Petrus, E. J., Lawson, K. A., Bucci, L. R., and Blum, K. Randomized, double-masked, placebo-controlled clinical study of the effectiveness of zinc acetate lozenges on common cold symptoms in allergy-tested subjects. Curr Ther Res 1998;59:595-607.
Phillips, A., Davidson, M., and Greaves, M. W. Venous leg ulceration: evaluation of zinc treatment, serum zinc and rate of healing. Clin.Exp.Dermatol. 1977;2(4):395-399. View abstract.
Picot, J., Hartwell, D., Harris, P., Mendes, D., Clegg, A. J., and Takeda, A. The effectiveness of interventions to treat severe acute malnutrition in young children: a systematic review. Health Technol.Assess. 2012;16(19):1-316. View abstract.
Piermarocchi, S., Saviano, S., Parisi, V., Tedeschi, M., Panozzo, G., Scarpa, G., Boschi, G., and Lo, Giudice G. Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study. Eur.J.Ophthalmol. 2012;22(2):216-225. View abstract.
Polat, T. B., Uysalol, M., and Cetinkaya, F. Efficacy of zinc supplementation on the severity and duration of diarrhea in malnourished Turkish children. Pediatr Int 2003;45(5):555-559. View abstract.
Pories, W. J., Henzel, J. H., Rob, C. G., and Strain, W. H. Acceleration of healing with zinc sulfate. Ann.Surg. 1967;165(3):432-436. View abstract.
Pories, W. J., Henzel, J. H., Rob, C. G., and Strain, W. H. Acceleration of wound healing in man with zinc sulphate given by mouth. Lancet 1-21-1967;1(7482):121-124. View abstract.
Prasad, A. S. and Cossack, Z. T. Zinc in sickle cell disease. Trans.Assoc.Am.Physicians 1983;96:246-251. View abstract.
Prasad, A. S. and Cossack, Z. T. Zinc supplementation and growth in sickle cell disease. Ann Intern Med 1984;100(3):367-371. View abstract.
Prasad, A. S. Zinc: role in immunity, oxidative stress and chronic inflammation. Curr Opin.Clin Nutr Metab Care 2009;12(6):646-652. View abstract.
Prasad, A. S., Abbasi, A. A., Rabbani, P., and DuMouchelle, E. Effect of zinc supplementation on serum testosterone level in adult male sickle cell anemia subjects. Am.J.Hematol. 1981;10(2):119-127. View abstract.
Prasad, A. S., Beck, F. W., Bao, B., Fitzgerald, J. T., Snell, D. C., Steinberg, J. D., and Cardozo, L. J. Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress. Am.J Clin Nutr. 2007;85(3):837-844. View abstract.
Prasad, A. S., Beck, F. W., Bao, B., Snell, D., and Fitzgerald, J. T. Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. J Infect.Dis. 3-15-2008;197(6):795-802. View abstract.
Prasad, A. S., Schoomaker, E. B., Ortega, J., Brewer, G. J., Oberleas, D., and Oelshlegel, F. J., Jr. Zinc deficiency in sickle cell disease. Clin Chem. 1975;21(4):582-587. View abstract.
Prasad, A., Beck, F. W., Bao, B., Fitzgerald, J. T., Snell, D. C., and Steinberg, J. D. Zinc supplementation decreases incidence of infections and hospital admissions in sickle cell disease (SCD). Am J Clin Nutr 2007;85(3):837-844.
Precocious puberty from ointment used for diaper rash-Phillips Corona Ointment. Nurses Drug Alert 1985;9:1-26.
Rahman, M. J., Sarker, P., Roy, S. K., Ahmad, S. M., Chisti, J., Azim, T., Mathan, M., Sack, D., Andersson, J., and Raqib, R. Effects of zinc supplementation as adjunct therapy on the systemic immune responses in shigellosis. Am J Clin Nutr 2005;81(2):495-502. View abstract.
Rahman, M. M., Vermund, S. H., Wahed, M. A., Fuchs, G. J., Baqui, A. H., and Alvarez, J. O. Simultaneous zinc and vitamin A supplementation in Bangladeshi children: randomised double blind controlled trial. BMJ 8-11-2001;323(7308):314-318. View abstract.
Rashidi, A. A., Salehi, M., Piroozmand, A., and Sagheb, M. M. Effects of zinc supplementation on serum zinc and C-reactive protein concentrations in hemodialysis patients. J Ren Nutr 2009;19(6):475-478. View abstract.
Rebello, T., Atherton, D. J., and Holden, C. The effect of oral zinc administration on sebum free fatty acids in acne vulgaris. Acta Derm.Venereol. 1986;66(4):305-310. View abstract.
Reding, P., Duchateau, J., and Bataille, C. Oral zinc supplementation improves hepatic encephalopathy. Results of a randomised controlled trial. Lancet 9-1-1984;2(8401):493-495. View abstract.
Reich, E. N. and Church, J. A. Oral zinc supplementation in the treatment of HIV-infected children. Pediatr.AIDS HIV.Infect. 1994;5(6):357-360. View abstract.
Richard, S. A., Zavaleta, N., Caulfield, L. E., Black, R. E., Witzig, R. S., and Shankar, A. H. Zinc and iron supplementation and malaria, diarrhea, and respiratory infections in children in the Peruvian Amazon. Am.J Trop.Med.Hyg. 2006;75(1):126-132. View abstract.
Rico, J. A., Kordas, K., Lopez, P., Rosado, J. L., Vargas, G. G., Ronquillo, D., and Stoltzfus, R. J. Efficacy of iron and/or zinc supplementation on cognitive performance of lead-exposed Mexican schoolchildren: a randomized, placebo-controlled trial. Pediatrics 2006;117(3):e518-e527. View abstract.
Riggio, O., Ariosto, F., Merli, M., Caschera, M., Zullo, A., Balducci, G., Ziparo, V., Pedretti, G., Fiaccadori, F., Bottari, E., and . Short-term oral zinc supplementation does not improve chronic hepatic encephalopathy. Results of a double-blind crossover trial. Dig.Dis.Sci 1991;36(9):1204-1208. View abstract.
Ripamonti, C. and Fulfaro, F. Taste alterations in cancer patients. J Pain Symptom.Manage. 1998;16(6):349-351. View abstract.
Robertson, J. S., Heywood, B., and Atkinson, S. M. Zinc supplementation during pregnancy. J.Public Health Med. 1991;13(3):227-229. View abstract.
Roig, Catala E., Iborra, Baviera J., Errando, Mariscal J., and Lerma, Berenguer J. [Clinical trial of zinc epsilon-acetamidocaproate (A-84) in duodenal ulcer]. Rev.Esp.Enferm.Apar.Dig. 1984;66(4):302-306. View abstract.
Rosado, J. L., Bourges, H., and Saint-Martin, B. [Vitamin and mineral deficiency in Mexico. A critical review of the state of the art. I. Mineral deficiency]. Salud Publica Mex. 1995;37(2):130-139. View abstract.
Rosado, J. L., Lopez, P., Munoz, E., Martinez, H., and Allen, L. H. Zinc supplementation reduced morbidity, but neither zinc nor iron supplementation affected growth or body composition of Mexican preschoolers. Am.J.Clin.Nutr. 1997;65(1):13-19. View abstract.
Ross, C., Morriss, A., Khairy, M., Khalaf, Y., Braude, P., Coomarasamy, A., and El-Toukhy, T. A systematic review of the effect of oral antioxidants on male infertility. Reprod.Biomed.Online. 2010;20(6):711-723. View abstract.
Ross, S. M., Nel, E., and Naeye, R. L. Differing effects of low and high bulk maternal dietary supplements during pregnancy. Early Hum.Dev. 1985;10(3-4):295-302. View abstract.
Roth, D. E., Richard, S. A., and Black, R. E. Zinc supplementation for the prevention of acute lower respiratory infection in children in developing countries: meta-analysis and meta-regression of randomized trials. Int J Epidemiol. 2010;39(3):795-808. View abstract.
Roussel, A. M., Kerkeni, A., Zouari, N., Mahjoub, S., Matheau, J. M., and Anderson, R. A. Antioxidant effects of zinc supplementation in Tunisians with type 2 diabetes mellitus. J Am.Coll.Nutr 2003;22(4):316-321. View abstract.
Rowe, J, McCall, E., and Kent, B. Clinical effectiveness of barrier preparations in the prevention and treatment of nappy dermatitis in infants and preschool children of nappy age. Int J Evid Based Healthc 2008;6:3-23.
Roy, S. K., Hossain, M. J., Khatun, W., Chakraborty, B., Chowdhury, S., Begum, A., Mah-e-Muneer, Shafique, S., Khanam, M., and Chowdhury, R. Zinc supplementation in children with cholera in Bangladesh: randomised controlled trial. BMJ 2-2-2008;336(7638):266-268. View abstract.
Roy, S. K., Raqib, R., Khatun, W., Azim, T., Chowdhury, R., Fuchs, G. J., and Sack, D. A. Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh. Eur J Clin Nutr 2008;62(7):849-855. View abstract.
Roy, S. K., Tomkins, A. M., Akramuzzaman, S. M., Chakraborty, B., Ara, G., Biswas, R., Islam, K. E., Khatun, W., and Jolly, S. P. Impact of zinc supplementation on subsequent morbidity and growth in Bangladeshi children with persistent diarrhoea. J Health Popul.Nutr. 2007;25(1):67-74. View abstract.
Roy, S. K., Tomkins, A. M., Haider, R., Akramuzzaman, S. M., and Behrens, R. Impact of zinc supplementation on subsequent growth and morbidity in Bangladeshi children with acute diarrhoea [abstract]. 1991;
Roy, S. K., Tomkins, A. M., Mahalanabis, D., Akramuzzaman, S. M., Haider, R., Behrens, R. H., and Fuchs, G. Impact of zinc supplementation on persistent diarrhoea in malnourished Bangladeshi children. Acta Paediatr. 1998;87(12):1235-1239. View abstract.
Roy, S. K., Tornkins, A. M., Haider, R., Akramuzzaman, S. M., Behren, R. H., and Mahalanabis, D. Impact of zinc supplementation on subsequent growth and morbidity in children presenting with persistent diarrhoea syndrome (PDS) in Bangladesh [Abstract]. 1994;
Ruel, M. T., Rivera, J. A., Santizo, M. C., Lonnerdal, B., and Brown, K. H. Impact of zinc supplementation on morbidity from diarrhea and respiratory infections among rural Guatemalan children. Pediatrics 1997;99(6):808-813. View abstract.
Saaka, M., Oosthuizen, J., and Beatty, S. Effect of prenatal zinc supplementation on birthweight. J Health Popul.Nutr 2009;27(5):619-631. View abstract.
Sachdev, H. P., Mittal, N. K., and Yadav, H. S. Oral zinc supplementation in persistent diarrhoea in infants. Ann.Trop.Paediatr. 1990;10(1):63-69. View abstract.
Sachdev, H. P., Mittal, N. K., Mittal, S. K., and Yadav, H. S. A controlled trial on utility of oral zinc supplementation in acute dehydrating diarrhea in infants. J Pediatr.Gastroenterol.Nutr 1988;7(6):877-881. View abstract.
Safai-Kutti, S. and Kutti, J. Zinc supplementation in anorexia nervosa. Am J Clin Nutr. 1986;44(4):581-582. View abstract.
Safai-Kutti, S. Oral zinc supplementation in anorexia nervosa. Acta Psychiatr.Scand.Suppl 1990;361:14-17. View abstract.
Safai-Kutti, S., Selin, E., Larsson, S., Jagenburg, R., Denfors, I., Sten, G., and Kjellmer, I. Zinc therapy in children with cystic fibrosis. Beitr.Infusionsther. 1991;27:104-114. View abstract.
Sakagami, M., Ikeda, M., Tomita, H., Ikui, A., Aiba, T., Takeda, N., Inokuchi, A., Kurono, Y., Nakashima, M., Shibasaki, Y., and Yotsuya, O. A zinc-containing compound, Polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study. Acta Otolaryngol. 11-26-2008;1-6. View abstract.
Sakai, F., Yoshida, S., Endo, S., and Tomita, H. [Therapeutic efficacy of zinc picolinate in patients with taste disorders]. Nippon Jibiinkoka Gakkai Kaiho 1995;98(7):1135-1139. View abstract.
Sakai, F., Yoshida, S., Endo, S., and Tomita, H. Double-blind, placebo-controlled trial of zinc picolinate for taste disorders. Acta Otolaryngol.Suppl 2002;(546):129-133. View abstract.
Salmenpera, L., Perheentupa, J., Nanto, V., and Siimes, M. A. Low zinc intake during exclusive breast-feeding does not impair growth. J.Pediatr.Gastroenterol.Nutr. 1994;18(3):361-370. View abstract.
Samman, S. and Roberts, D. C. The effect of zinc supplements on lipoproteins and copper status. Atherosclerosis 1988;70(3):247-252. View abstract.
Sandstead, H. H., Prasad, A. S., Penland, J. G., Beck, F. W., Kaplan, J., Egger, N. G., Alcock, N. W., Carroll, R. M., Ramanujam, V. M., Dayal, H. H., Rocco, C. D., Plotkin, R. A., and Zavaleta, A. N. Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteins. Am J Clin Nutr 2008;88(4):1067-1073. View abstract.
Saper, R. B. and Rash, R. Zinc: an essential micronutrient. Am Fam.Physician 5-1-2009;79(9):768-772. View abstract.
Sarris, J., Kean, J., Schweitzer, I., and Lake, J. Complementary medicines (herbal and nutritional products) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD): a systematic review of the evidence. Complement Ther Med 2011;19(4):216-227. View abstract.
Sawada, T. and Yokoi, K. Effect of zinc supplementation on mood states in young women: a pilot study. Eur J Clin Nutr 2010;64(3):331-333. View abstract.
Saxton, C. A., Harrap, G. J., and Lloyd, A. M. The effect of dentifrices containing zinc citrate on plaque growth and oral zinc levels. J.Clin.Periodontol. 1986;13(4):301-306. View abstract.
Sazawal, S., Black, R. E., Bhan, M. K., Jalla, S., Bhandari, N., Sinha, A., and Majumdar, S. Zinc supplementation reduces the incidence of persistent diarrhea and dysentery among low socioeconomic children in India. J.Nutr. 1996;126(2):443-450. View abstract.
Sazawal, S., Black, R. E., Bhan, M. K., Jalla, S., Sinha, A., and Bhandari, N. Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea--a community-based, double-blind, controlled trial. Am.J.Clin.Nutr. 1997;66(2):413-418. View abstract.
Sazawal, S., Black, R. E., Jalla, S., Mazumdar, S., Sinha, A., and Bhan, M. K. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. Pediatrics 1998;102(1 Pt 1):1-5. View abstract.
Sazawal, S., Black, R. E., Ramsan, M., Chwaya, H. M., Dutta, A., Dhingra, U., Stoltzfus, R. J., Othman, M. K., and Kabole, F. M. Effect of zinc supplementation on mortality in children aged 1-48 months: a community-based randomised placebo-controlled trial. Lancet 3-17-2007;369(9565):927-934. View abstract.
Sazawal, S., Jalla, S., Mazumder, S., Sinha, A., Black, R. E., and Bhan, M. K. Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children. Indian Pediatr. 1997;34(7):589-597. View abstract.
Schlesinger, L., Arevalo, M., Arredondo, S., Diaz, M., Lonnerdal, B., and Stekel, A. Effect of a zinc-fortified formula on immunocompetence and growth of malnourished infants. Am.J.Clin.Nutr. 1992;56(3):491-498. View abstract.
Scholl, T. O., Hediger, M. L., Schall, J. I., Fischer, R. L., and Khoo, C. S. Low zinc intake during pregnancy: its association with preterm and very preterm delivery. Am.J Epidemiol. 5-15-1993;137(10):1115-1124. View abstract.
Segreto, V. A., Collins, E. M., D'Agostino, R., Cancro, L. P., Pfeifer, H. J., and Gilbert, R. J. Anticalculus effect of a dentifrice containing 0.5% zinc citrate trihydrate. Community Dent.Oral Epidemiol. 1991;19(1):29-31. View abstract.
Selimoglu, M. A., Ertekin, V., Doneray, H., and Yildirim, M. Bone mineral density of children with Wilson disease: efficacy of penicillamine and zinc therapy. J Clin Gastroenterol. 2008;42(2):194-198. View abstract.
Serjeant, G. R., Galloway, R. E., and Gueri, M. C. Oral zinc sulphate in sickle-cell ulcers. Lancet 10-31-1970;2(7679):891-892. View abstract.
Shah, D. R., Singh, P. P., Gupta, R. C., and Bhandari, T. K. Effect of oral zinc sulphate on serum lipids and lipoproteins in human subjects. Indian J Physiol Pharmacol. 1988;32(1):47-50. View abstract.
Shankar, A. H., Genton, B., Baisor, M., Paino, J., Tamja, S., Adiguma, T., Wu, L., Rare, L., Bannon, D., Tielsch, J. M., West, K. P., Jr., and Alpers, M. P. The influence of zinc supplementation on morbidity due to Plasmodium falciparum: a randomized trial in preschool children in Papua New Guinea. Am.J.Trop.Med.Hyg. 2000;62(6):663-669. View abstract.
Shankar, A. H., Genton, B., Tamja, S., Arnold, S., and Wu, L. Zinc Supplementation can Reduce Malaria-Related Morbidity in Preschool Children. American Journal of Tropical Medicine and Hygiene 1997;57(3 Suppl/1):434.
Sharquie, K. E., Khorsheed, A. A., and Al-Nuaimy, A. A. Topical zinc sulphate solution for treatment of viral warts. Saudi.Med.J 2007;28(9):1418-1421. View abstract.
Sharquie, K. E., Najim, R. A., Farjou, I. B., and Al Timimi, D. J. Oral zinc sulphate in the treatment of acute cutaneous leishmaniasis. Clin.Exp.Dermatol. 2001;26(1):21-26. View abstract.
Sheikh, A., Shamsuzzaman, S., Ahmad, S. M., Nasrin, D., Nahar, S., Alam, M. M., Al, Tarique A., Begum, Y. A., Qadri, S. S., Chowdhury, M. I., Saha, A., Larson, C. P., and Qadri, F. Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea. J Nutr 2010;140(5):1049-1056. View abstract.
Sheng, X. Y., Hambidge, K. M., Krebs, N. F., Lei, S., Westcott, J. E., and Miller, L. V. Dysprosium as a nonabsorbable fecal marker in studies of zinc homeostasis. Am J Clin Nutr 2005;82(5):1017-1023. View abstract.
Shidfar, F., Aghasi, M., Vafa, M., Heydari, I., Hosseini, S., and Shidfar, S. Effects of combination of zinc and vitamin A supplementation on serum fasting blood sugar, insulin, apoprotein B and apoprotein A-I in patients with type I diabetes. Int.J Food Sci Nutr 2010;61(2):182-191. View abstract.
Siegfried, N., Irlam, J. H., Visser, M. E., and Rollins, N. N. Micronutrient supplementation in pregnant women with HIV infection. Cochrane.Database.Syst.Rev. 2012;3:CD009755. View abstract.
Simkin, P. A. Zinc sulphate in rheumatoid arthritis. Prog.Clin Biol.Res 1977;14:343-356. View abstract.
Simmer, K. and Thompson, R. P. Maternal zinc and intrauterine growth retardation. Clin Sci (Lond) 1985;68(4):395-399. View abstract.
Simmer, K., Khanum, S., Carlsson, L., and Thompson, R. P. Nutritional rehabilitation in Bangladesh--the importance of zinc. Am.J.Clin.Nutr. 1988;47(6):1036-1040. View abstract.
Simmer, K., Lort-Phillips, L., James, C., and Thompson, R. P. A double-blind trial of zinc supplementation in pregnancy. Eur J Clin Nutr 1991;45(3):139-144. View abstract.
Simonart, T. and de, Maertelaer, V. Systemic treatments for cutaneous warts: a systematic review. J Dermatolog.Treat. 2012;23(1):72-77. View abstract.
Sinclair, D., Abba, K., Grobler, L., and Sudarsanam, T. D. Nutritional supplements for people being treated for active tuberculosis. Cochrane.Database.Syst.Rev. 2011;(11):CD006086. View abstract.
Singh, M. and Das, R. R. Zinc for the common cold. Cochrane Database.Syst.Rev 2011;2:CD001364. View abstract.
Singh, P. C. and Ballas, S. K. Drugs for preventing red blood cell dehydration in people with sickle cell disease. Cochrane Database.Syst.Rev 2007;(4):CD003426. View abstract.
Siwek, M., Dudek, D., Paul, I. A., Sowa-Kucma, M., Zieba, A., Popik, P., Pilc, A., and Nowak, G. Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. J Affect.Disord. 2009;118(1-3):187-195. View abstract.
Siwek, M., Dudek, D., Schlegel-Zawadzka, M., Morawska, A., Piekoszewski, W., Opoka, W., Zieba, A., Pilc, A., Popik, P., and Nowak, G. Serum zinc level in depressed patients during zinc supplementation of imipramine treatment. J Affect.Disord. 2010;126(3):447-452. View abstract.
Soderberg, T., Hallmans, G., Stenstrom, S., Lobo, D., Pinto, J., Maroof, S., and Vellut, C. Treatment of leprosy wounds with adhesive zinc tape. Lepr.Rev. 1982;53(4):271-276. View abstract.
Sprenger, K. B., Schmitz, J., Hetzel, D., Bundschu, D., and Franz, H. E. Zinc and sexual dysfunction. Contrib.Nephrol. 1984;38:119-128. View abstract.
Stabile, A., Pesaresi, M. A., Stabile, A. M., Pastore, M., Sopo, S. M., Ricci, R., Celestini, E., and Segni, G. Immunodeficiency and plasma zinc levels in children with Down's syndrome: a long-term follow-up of oral zinc supplementation. Clin Immunol.Immunopathol. 1991;58(2):207-216. View abstract.
Stadtler, P. [Toothpastes--effects of zinc salts on cleansing action]. Z.Stomatol. 1987;84(7):351-355. View abstract.
Stefani, M., Bottino, G., Fontenelle, E., and Azulay, D. R. [Efficacy comparison between cimetidine and zinc sulphate in the treatment of multiple and recalcitrant warts]. An.Bras.Dermatol. 2009;84(1):23-29. View abstract.
Stewart-Knox, B. J., Simpson, E. E., Parr, H., Rae, G., Polito, A., Intorre, F., Andriollo, Sanchez M., Meunier, N., O'Connor, J. M., Maiani, G., Coudray, C., and Strain, J. J. Taste acuity in response to zinc supplementation in older Europeans. Br J Nutr 2008;99(1):129-136. View abstract.
Strand, T. A., Chandyo, R. K., Bahl, R., Sharma, P. R., Adhikari, R. K., Bhandari, N., Ulvik, R. J., Molbak, K., Bhan, M. K., and Sommerfelt, H. Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children. Pediatrics 2002;109(5):898-903. View abstract.
Stratton, J. and Godwin, M. The effect of supplemental vitamins and minerals on the development of prostate cancer: a systematic review and meta-analysis. Fam.Pract. 2011;28(3):243-252. View abstract.
Sturniolo, G. C., Di, Leo, V, Ferronato, A., D'Odorico, A., and D'Inca, R. Zinc supplementation tightens "leaky gut" in Crohn's disease. Inflamm.Bowel.Dis 2001;7(2):94-98. View abstract.
Subudhi, A. W., Jacobs, K. A., Hagobian, T. A., Fattor, J. A., Muza, S. R., Fulco, C. S., Cymerman, A., and Friedlander, A. L. Changes in ventilatory threshold at high altitude: effect of antioxidants. Med Sci Sports Exerc. 2006;38(8):1425-1431. View abstract.
Sundaram, V. and Shaikh, O. S. Hepatic encephalopathy: pathophysiology and emerging therapies. Med Clin North Am 2009;93(4):819-36, vii. View abstract.
Sur, D., Gupta, D. N., Mondal, S. K., Ghosh, S., Manna, B., Rajendran, K., and Bhattacharya, S. K. Impact of zinc supplementation on diarrheal morbidity and growth pattern of low birth weight infants in kolkata, India: a randomized, double-blind, placebo-controlled, community-based study. Pediatrics 2003;112(6 Pt 1):1327-1332. View abstract.
Swanson, C. A. and King, J. C. Zinc utilization in pregnant and nonpregnant women fed controlled diets providing the zinc RDA. J Nutr 1982;112(4):697-707. View abstract.
Takihara, H., Cosentino, M. J., and Cockett, A. T. Zinc sulfate therapy for infertile male with or without varicocelectomy. Urology 1987;29(6):638-641. View abstract.
Taly, A. B., Meenakshi-Sundaram, S., Sinha, S., Swamy, H. S., and Arunodaya, G. R. Wilson disease: description of 282 patients evaluated over 3 decades. Medicine (Baltimore) 2007;86(2):112-121. View abstract.
Tamura, T., Goldenberg, R. L., Ramey, S. L., Nelson, K. G., and Chapman, V. R. Effect of zinc supplementation of pregnant women on the mental and psychomotor development of their children at 5 y of age. Am.J Clin Nutr. 2003;77(6):1512-1516. View abstract.
Tamura, T., Olin, K. L., Goldenberg, R. L., Johnston, K. E., DuBard, M. B., and Keen, C. L. Plasma extracellular superoxide dismutase activity in healthy pregnant women is not influenced by zinc supplementation. Biol.Trace Elem.Res. 2001;80(2):107-113. View abstract.
Taneja, S., Bhandari, N., Bahl, R., and Bhan, M. K. Impact of zinc supplementation on mental and psychomotor scores of children aged 12 to 18 months: a randomized, double-blind trial. J Pediatr 2005;146(4):506-511. View abstract.
Taneja, S., Bhandari, N., Rongsen-Chandola, T., Mahalanabis, D., Fontaine, O., and Bhan, M. K. Effect of zinc supplementation on morbidity and growth in hospital-born, low-birth-weight infants. Am J Clin Nutr 2009;90(2):385-391. View abstract.
Taneja, S., Strand, T. A., Sommerfelt, H., Bahl, R., and Bhandari, N. Zinc supplementation for four months does not affect growth in young north Indian children. J Nutr 2010;140(3):630-634. View abstract.
Tang, Y., Yang, Q., Lu, J., Zhang, X., Suen, D., Tan, Y., Jin, L., Xiao, J., Xie, R., Rane, M., Li, X., and Cai, L. Zinc supplementation partially prevents renal pathological changes in diabetic rats. J Nutr Biochem. 2010;21(3):237-246. View abstract.
Tengrup, I., Ahonen, J., and Zederfeldt, B. Granulation tissue formation in zinc-treated rats. Acta Chir Scand. 1980;146(1):1-4. View abstract.
The Age-Related Eye Disease Study (AREDS): design implications. AREDS report no. 1. Control Clin.Trials 1999;20(6):573-600. View abstract.
Theodoratou, E., Al-Jilaihawi, S., Woodward, F., Ferguson, J., Jhass, A., Balliet, M., Kolcic, I., Sadruddin, S., Duke, T., Rudan, I., and Campbell, H. The effect of case management on childhood pneumonia mortality in developing countries. Int J Epidemiol 2010;39 Suppl 1:i155-i171. View abstract.
Thrane, P. S., Jonski, G., Young, A., and Rolla, G. Zn and CHX mouthwash effective against VSCs responsible for halitosis for up to 12 hours. Dent Health 2009;48(3):8-12.
Tielsch, J. M., Khatry, S. K., Stoltzfus, R. J., Katz, J., LeClerq, S. C., Adhikari, R., Mullany, L. C., Black, R., and Shresta, S. Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trial. Lancet 10-6-2007;370(9594):1230-1239. View abstract.
Tielsch, J. M., Khatry, S. K., Stoltzfus, R. J., Katz, J., LeClerq, S. C., Adhikari, R., Mullany, L. C., Shresta, S., and Black, R. E. Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial. Lancet 1-14-2006;367(9505):144-152. View abstract.
Tikkiwal, M, Ajmera, RL, and Mathur, NK. Effect of Zinc Administration on Seminal Zinc and Fertility of Oligospermic Males. Indian J.Physiol Pharmacol. 1987;31(1):30-34.
Tremellen, K., Miari, G., Froiland, D., and Thompson, J. A randomised control trial examining the effect of an antioxidant (Menevit) on pregnancy outcome during IVF-ICSI treatment. Aust.N.Z.J Obstet.Gynaecol. 2007;47(3):216-221. View abstract.
Trubiani, O., Antonucci, A., Palka, G., and Di Primio, R. Programmed cell death of peripheral myeloid precursor cells in Down patients: effect of zinc therapy. Ultrastruct.Pathol. 1996;20(5):457-462. View abstract.
Tupe, R. P. and Chiplonkar, S. A. Zinc supplementation improved cognitive performance and taste acuity in Indian adolescent girls. J Am Coll.Nutr 2009;28(4):388-396. View abstract.
Tuttle, S., Aggett, P. J., Campbell, D., and MacGillivray, I. Zinc and copper nutrition in human pregnancy: a longitudinal study in normal primigravidae and in primigravidae at risk of delivering a growth retarded baby. Am J Clin Nutr 1985;41(5):1032-1041. View abstract.
Vahlquist, A., Michaelsson, G., and Juhlin, L. Acne treatment with oral zinc and vitamin A: effects on the serum levels of zinc and retinol binding protein (RBP). Acta Derm.Venereol. 1978;58(5):437-442. View abstract.
Valavi, E., Hakimzadeh, M., Shamsizadeh, A., Aminzadeh, M., and Alghasi, A. The efficacy of zinc supplementation on outcome of children with severe pneumonia. A randomized double-blind placebo-controlled clinical trial. Indian J Pediatr. 2011;78(9):1079-1084. View abstract.
Valentiner-Branth, P. [The effect of zinc therapy on common cold--a survey of a Cochrane review]. Ugeskr.Laeger 1-9-2012;174(1-2):36-38. View abstract.
Valentiner-Branth, P., Shrestha, P. S., Chandyo, R. K., Mathisen, M., Basnet, S., Bhandari, N., Adhikari, R. K., Sommerfelt, H., and Strand, T. A. A randomized controlled trial of the effect of zinc as adjuvant therapy in children 2-35 mo of age with severe or nonsevere pneumonia in Bhaktapur, Nepal. Am J Clin Nutr 2010;91(6):1667-1674. View abstract.
Valery, P. C., Torzillo, P. J., Boyce, N. C., White, A. V., Stewart, P. A., Wheaton, G. R., Purdie, D. M., Wakerman, J., and Chang, A. B. Zinc and vitamin A supplementation in Australian Indigenous children with acute diarrhoea: a randomised controlled trial. Med J Aust. 5-16-2005;182(10):530-535. View abstract.
Varas Lorenzo, M. J. Zinc acexamate and ranitidine in the short- and mid-term management of gastroduodenal ulcers. Curr Ther Res 21986;39:19-29.
Varas Lorenzo, M. J., Lopez, Martinez A., Gordillo, Bernal J., and Mundet, Surroca J. [Comparative study of 3 drugs (aceglutamide aluminum, zinc acexamate, and magaldrate) in the long-term maintenance treatment (1 year) of peptic ulcer]. Rev.Esp.Enferm.Dig. 1991;80(2):91-94. View abstract.
Vasudevan, A., Shendurnikar, N., and Kotecha, P. V. Zinc supplementation in severe malnutrition. Indian Pediatr. 1997;34(3):236-238. View abstract.
Vecchio, M., Navaneethan, S. D., Johnson, D. W., Lucisano, G., Graziano, G., Querques, M., Saglimbene, V., Ruospo, M., Bonifati, C., Jannini, E. A., and Strippoli, G. F. Treatment options for sexual dysfunction in patients with chronic kidney disease: a systematic review of randomized controlled trials. Clin J Am Soc Nephrol. 2010;5(6):985-995. View abstract.
Vecchio, M., Navaneethan, S. D., Johnson, D. W., Lucisano, G., Graziano, G., Saglimbene, V., Ruospo, M., Querques, M., Jannini, E. A., and Strippoli, G. F. Interventions for treating sexual dysfunction in patients with chronic kidney disease. Cochrane Database Syst Rev 2010;(12):CD007747. View abstract.
Velasco-Reynold, C., Navarro-Alarcon, M., Lopez, G., Perez-Valero, V., and Lopez-Martinez, M. C. In vitro determination of zinc dialyzability from duplicate hospital meals: influence of other nutrients. Nutrition 2008;24(1):84-93. View abstract.
Velie, E. M., Block, G., Shaw, G. M., Samuels, S. J., Schaffer, D. M., and Kulldorff, M. Maternal supplemental and dietary zinc intake and the occurrence of neural tube defects in California. Am J Epidemiol. 9-15-1999;150(6):605-616. View abstract.
Verma, K. C., Saini, A. S., and Dhamija, S. K. Oral zinc sulphate therapy in acne vulgaris: a double-blind trial. Acta Derm.Venereol. 1980;60(4):337-340. View abstract.
Veverka, D. V., Wilson, C., Martinez, M. A., Wenger, R., and Tamosuinas, A. Use of zinc supplements to reduce upper respiratory infections in United States Air Force Academy cadets. Complement Ther Clin Pract 2009;15(2):91-95. View abstract.
Villamor, E., Aboud, S., Koulinska, I. N., Kupka, R., Urassa, W., Chaplin, B., Msamanga, G., and Fawzi, W. W. Zinc supplementation to HIV-1-infected pregnant women: effects on maternal anthropometry, viral load, and early mother-to-child transmission. Eur.J Clin Nutr. 2006;60(7):862-869. View abstract.
Vir, S. C., Love, A. H., and Thompson, W. Zinc concentration in hair and serum of pregnant women in Belfast. Am J Clin Nutr 1981;34(12):2800-2807. View abstract.
Voorhees, J. J., Chakrabarti, S. G., Botero, F., Miedler, L., and Harrell, E. R. Zinc therapy and distribution in psoriasis. Arch.Dermatol. 1969;100(6):669-673. View abstract.
Voss, Jepsen L. and Clemmensen, K. Zinc in Danish women during late normal pregnancy and pregnancies with intra-uterine growth retardation. Acta Obstet.Gynecol.Scand 1987;66(5):401-405. View abstract.
Wabrek, A. J. A possible role in the reversal of uremic impotence. Sexuality and Disability 1982;5(4):213-221.
Wahba, A. Topical application of zinc-solutions: a new treatment for herpes simplex infections of the skin? Acta Derm.Venereol. 1980;60(2):175-177. View abstract.
Walker, C. L. and Black, R. E. Zinc for the treatment of diarrhoea: effect on diarrhoea morbidity, mortality and incidence of future episodes. Int J Epidemiol. 2010;39 Suppl 1:i63-i69. View abstract.
Walker, C. L., Bhutta, Z. A., Bhandari, N., Teka, T., Shahid, F., Taneja, S., and Black, R. E. Zinc during and in convalescence from diarrhea has no demonstrable effect on subsequent morbidity and anthropometric status among infants <6 mo of age. Am J Clin Nutr 2007;85(3):887-894. View abstract.
Wang, H., Li, R. X., and Wang, M. F. Effects of zinc and antioxidant on visual function of patients with age-related macular degeneration. Zhongguo Linchuant Kangfu 2004;8:1290-1291.
Watkinson, M., Aggett, P. J., and Cole, T. J. Zinc and acute tropical ulcers in Gambian children and adolescents. Am.J.Clin.Nutr. 1985;41(1):43-51. View abstract.
Wazewska-Czyzewska, M., Wesierska-Gadek, J., and Legutko, L. Immunostimulatory effect of zinc in patients with acute lymphoblastic leukemia. Folia Haematol.Int.Mag.Klin.Morphol.Blutforsch. 1978;105(6):727-732. View abstract.
Weimar, V. M., Puhl, S. C., Smith, W. H., and tenBroeke, J. E. Zinc sulfate in acne vulgaris. Arch.Dermatol. 1978;114(12):1776-1778. View abstract.
Weismann, K., Christensen, E., and Dreyer, V. Zinc supplementation in alcoholic cirrhosis. A double-blind clinical trial. Acta Med Scand. 1979;205(5):361-366. View abstract.
Wilkinson, E. A. and Hawke, C. I. Does oral zinc aid the healing of chronic leg ulcers? A systematic literature review. Arch.Dermatol. 1998;134(12):1556-1560. View abstract.
Wilkinson, E. A. Oral zinc for arterial and venous leg ulcers. Cochrane.Database.Syst.Rev. 2012;8:CD001273. View abstract.
Wilkinson, J. T. and Fraunfelder, F. W. Use of herbal medicines and nutritional supplements in ocular disorders: an evidence-based review. Drugs 12-24-2011;71(18):2421-2434. View abstract.
Winch, P. J., Gilroy, K. E., Doumbia, S., Patterson, A. E., Daou, Z., Diawara, A., Swedberg, E., Black, R. E., and Fontaine, O. Operational issues and trends associated with the pilot introduction of zinc for childhood diarrhoea in Bougouni district, Mali. J Health Popul.Nutr 2008;26(2):151-162. View abstract.
Windfuhr, J. P., Cao, Van H., and Landis, B. N. Recovery from long-lasting post-tonsillectomy dysgeusia. Oral Surg.Oral Med Oral Pathol.Oral Radiol.Endod. 2010;109(1):e11-e14. View abstract.
Worthington, H. V., Clarkson, J. E., and Eden, O. B. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane.Database.Syst.Rev. 2007;(4):CD000978. View abstract.
Wuehler, S. E., Sempertegui, F., and Brown, K. H. Dose-response trial of prophylactic zinc supplements, with or without copper, in young Ecuadorian children at risk of zinc deficiency. Am J Clin Nutr 2008;87(3):723-733. View abstract.
Xie, L., Chen, X., and Pan, J. The effects of zinc supplementation to Chinese rural pregnant women and their pregnancy outcome. Journal of Shanghai Second Medical University 2001;13(2):119-124.
Yaghoobi, R., Sadighha, A., and Baktash, D. Evaluation of oral zinc sulfate effect on recalcitrant multiple viral warts: a randomized placebo-controlled clinical trial. J Am Acad.Dermatol. 2009;60(4):706-708. View abstract.
Yakoob, M. Y., Theodoratou, E., Jabeen, A., Imdad, A., Eisele, T. P., Ferguson, J., Jhass, A., Rudan, I., Campbell, H., Black, R. E., and Bhutta, Z. A. Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria. BMC.Public Health 2011;11 Suppl 3:S23. View abstract.
Yamada, R. T. and Leone, C. R. Intrauterine growth restriction and zinc concentrations in term infants during the first month of life. J Am Coll.Nutr 2008;27(4):485-491. View abstract.
Yoshida, S., Endo, S., and Tomita, H. A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder. Auris Nasus Larynx 1991;18(2):153-161. View abstract.
Yuzbasiyan-Gurkan, V., Grider, A., Nostrant, T., Cousins, R. J., and Brewer, G. J. Treatment of Wilson's disease with zinc: X. Intestinal metallothionein induction. J Lab Clin Med 1992;120(3):380-386. View abstract.
Zeng, L. and Zhang, L. Efficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: systematic review. Trop.Med.Int Health 2011;16(12):1474-1482. View abstract.
Zetin, M. and Stone, R. A. Effects of zinc in chronic hemodialysis. Clin Nephrol. 1980;13(1):20-25. View abstract.
Zimmerman, A. W., Dunham, B. S., Nochimson, D. J., Kaplan, B. M., Clive, J. M., and Kunkel, S. L. Zinc transport in pregnancy. Am J Obstet.Gynecol. 7-1-1984;149(5):523-529. View abstract.
Zinc lozenges reduce the duration of common cold symptoms. Nutr.Rev. 1997;55(3):82-85. View abstract.
AAO Retina/Vitreous PPP Panel, Hoskins Center for Quality Eye Care. Age-Related Macular Degeneration PPP - Updated 2015. www.aao.org/preferred-practice-pattern/age-related-macular-degeneration-ppp-2015. Accessed 11 November 2016.
Abu-Hamdan DK, Desai H, Sondheimer J, et al. Taste acuity and zinc metabolism in captopril-treated hypertensive male patients. Am J Hypertens 1988;1:303S-8S. View abstract.
Abu-Hamdan DK, Mahajan SK, Migdal S, et al. Zinc tolerance test in uremia: effect of calcitriol supplementation. J Am Coll Nutr 1988;7:235-40. View abstract.
Adams CL, Hambridge M, Raboy V, et al. Zinc absorption from a low-phytic acid maize. Am J Clin Nutr 2002;76:556-9. View abstract.
Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS report no. 8. Arch Ophthalmol 2001;119:1417-36. View abstract.
Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 2001;119:1439-52. View abstract.
Age-Related Eye Disease Study Research Group. Potential public health impact of age-related eye disease study results: AREDS report no. 11. Arch Ophthalmol 2003;121:1621-4. View abstract.
Aggarwal R, Sentz J, Miller MA. Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: a meta-analysis. Pediatrics 2007;119:1120-30. View abstract.
Agren MS. Studies on zinc in wound healing. Acta Derm Venereol Suppl (Stockh) 1990;154:1-36. View abstract.
Agte VV, Chiplonkar SA, Gokhale MK. Interaction of riboflavin with zinc bioavailability. Ann NY Acad Sci 1992;669:314-6. View abstract.
Akhavan S, Mohammadi SR, Modarres Gillani M, Mousavi AS, Shirazi M. Efficacy of combination therapy of oral zinc sulfate with imiquimod, podophyllin or cryotherapy in the treatment of vulvar warts. J Obstet Gynaecol Res. 2014 Oct;40(10):2110-3. View abstract.
Akhondzadeh S, Mohammadi MR, Khademi M. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children :a double blind and randomized trial. BMC Psychiatry 2004;4:9. View abstract.
Akram M, Sullivan C, Mack G, Buchannan N. What is the clinical significance of reduced manganese and zinc levels in treated epileptic patients? Med J Australia 1989;15:113. View abstract.
Al-Nakib W, Higgins PG, Barrow I, et al. Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges. J Antimicrob Chemother 1987;20:893-901. View abstract.
Alexander TH, Davidson TM. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. Laryngoscope 2006;116:217-20. View abstract.
Allain P, Mauras Y, Premel-Cabic A, et al. Effects of an EDTA infusion on the urinary elimination of several elements in healthy subjects. Br J Clin Pharmacol 1991;31:347. View abstract.
Altunbasak S, Biatmakoui F, Baytok V, et al. Serum and hair zinc levels in epileptic children taking valproic acid. Biol Trace Element Res 1997;58;117-25. View abstract.
Amer M, Bahgat MR, Tosson Z, et al. Serum zinc in acne vulgaris. Int J Dermatol 1982;21:481-4. View abstract.
American Academy of Pediatrics Committee on Drugs. Treatment guidelines for lead exposure in children. Pediatrics 1995;96:155-60. View abstract.
Anderson LA, Hakojarvi SL, Boudreaux SK. Zinc acetate treatment in Wilson's disease. Ann Pharmacother 1998;32:78-87. View abstract.
Anon. Zinc Against Plasmodium Study Group. Effect of zinc on the treatment of Plasmodium falciparum malaria in children: a randomized controlled trial. Am J Clin Nutr 2002;76:805-12.. View abstract.
Antoniou LD, Shalhoub RJ, Elliot S. Zinc tolerance tests in chronic aremia. Clin Nephrol 1981;16:181-7. View abstract.
Antoniou LD, Shalhoub RJ, Sudhakar T, Smith JC Jr. Reversal of uraemic impotence by zinc. Lancet 1977;2:895-8. View abstract.
Arbabi-kalati F, Arbabi-kalati F, Deghatipour M, Ansari Moghadam A. Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: a double-blind randomized clinical trial. Arch Iran Med. 2012 Jul;15(7):413-7. View abstract.
Arens M, Travis S. Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. J Clin Microbiol 2000;38:1758-62. View abstract.
Arnold LE, Kleykamp D, Votolato NA, et al. Gamma-linolenic acid for attention-deficit hyperactivity disorder: Placebo-controlled comparison to D-amphetamine. Biol Psychiatry 1989;25:222-8. View abstract.
Arnold LE, Votolato NA, Kleykamp D, et al. Does hair zinc predict amphetamine improvement of ADD/hyperactivity? Int J Neurosci 1990;50:103-7.. View abstract.
Atik OS. Zinc and senile osteoporosis. J Am Geriatr Soc 1983;31:790-1. View abstract.
Attia EA, Belal DM, El Samahy MH, El Hamamsy MH. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life. Wound Repair Regen. 2014 Jan-Feb;22(1):52-7. View abstract.
Awh CC, Hawken S, Zanke BW. Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study. Ophthalmology. 2015 Jan;122(1):162-9. View abstract.
Aydinok Y, Coker C, Kavakli K, et al. Urinary zinc excretion and zinc status of patients with beta-thalassemia major. Biol Trace Elem Res 1999;70:165-72. View abstract.
Azizollahi G, Azizollahi S, Babaei H, Kianinejad M, Baneshi MR, Nematollahi-mahani SN. Effects of supplement therapy on sperm parameters, protamine content and acrosomal integrity of varicocelectomized subjects. J Assist Reprod Genet. 2013;30(4):593-9. View abstract.
Bamford JT, Gessert CE, Haller IV, Kruger K, Johnson BP. Randomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosacea. Int J Dermatol. 2012 Apr;51(4):459-62. View abstract.
Baqui AH, Black RE, El Arifeen S, et al. Effect of zinc supplementation started during diarrhoea on morbidity and mortality in Bangladeshi children: community randomised trial. BMJ 2002;325:1059-62.. View abstract.
Barak S, Katz J. The effect of Breezy candy on halitosis: a double-blind, controlled, and randomized study. Quintessence Int. 2012 Apr;43(4):313-7. View abstract.
Barceloux DG. Zinc. J Toxicol Clin Toxicol 1999;37:279-92. View abstract.
Barrett S. Zicam Marketers Sued. United States District Court Western District of Michigan Southern Division, Filed October 14, 2003, Case No. 4:03CV0146.
Basnet S, Shrestha PS, Sharma A, Mathisen M, Prasai R, Bhandari N, Adhikari RK, Sommerfelt H, Valentiner-Branth P, Strand TA; Zinc Severe Pneumonia Study Group. A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children. Pediatrics. 2012 Apr;129(4):701-8. View abstract.
Bekaroglu M, Aslan Y, Gedik Y, et al. Relationships between serum free fatty acids and zinc, and attention deficit hyperactivity disorder: a research note. J Child Psychol Psychiatry 1996;37:225-7.. View abstract.
Belongia EA, Berg R, Liu K. A randomized trial of zinc nasal spray for the treatment of upper respiratory illness in adults. Am J Med 2001;111:103-8. View abstract.
Benso L, Gambotto S, Pastorin L, et al. Growth velocity monitoring of the efficacy of different therapeutic protocols in a group of thalassaemic children. Eur J Pediatr 1995;154:205-8. View abstract.
Berger MM, Reymond MJ, Shenkin A, et al. Influence of selenium supplements on the post-traumatic alterations of the thyroid axis: a placebo-controlled trial. Intensive Care Med 2001;27:91-100.. View abstract.
Berger MM, Shenkin A, Revelly JP, et al. Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients. Am J Clin Nutr 2004;80:410-6. View abstract.
Berger MM, Spertini F, Shenkin A, et al. Trace element supplementation modulates pulmonary infection rates after major burns: a double-blind, placebo-controlled trial. Am J Clin Nutr 1998;68:365-71. View abstract.
Beutler KT, Pankewycz O, Brautigan DL. Equivalent uptake of organic and inorganic zinc by monkey kidney fibroblasts, human intestinal epithelial cells, or perfused mouse intestine. Biol Trace Elem Res 1998;61:19-31. View abstract.
Bhandari N, Bahl R, Taneja S, et al. Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. BMJ 2002;324:1358. View abstract.
Bhutta ZA, Bird SM, Black RE, et al. Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: pooled analysis of randomized controlled trials. Am J Clin Nutr 2000;72:1516-22. View abstract.
Bhutta ZA, Black RE, Brown KH, et al. Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. J Pediatr 1999;135:689-97. View abstract.
Bianchi GP, Marchesini G, Brizi M, et al. Nutritional effects of oral zinc supplementation in cirrhosis. Nutr Res 2000;20:1079-89.
Bilici M, Yildirim F, Kandil S, et al. Double-blind, placebo-controlled study of zinc sulfate in the treatment of attention deficit hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry 2004;28:181-90.. View abstract.
Birmingham CL, Goldner EM, Bakan R. Controlled trial of zinc supplementation in anorexia nervosa. Int J Eat Disord 1994;15:251-5. View abstract.
Bjorksten B, Back O, Gustavson KH, et al. Zinc and immune function in Down's syndrome. Acta Paediatr Scand 1980;69:183-7. View abstract.
Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999;21:3-40. View abstract.
Blostein-Fujii A, DiSilvestro RA, Frid D, et al. Short-term zinc supplementation in women with non-insulin-dependent diabetes mellitus: effects on plasma 5'-nucleotidase activities, insulin-like growth factor I concentrations, and lipoprotein oxidation rates in vitro. Am J Clin Nutr 1997;66:639-42. View abstract.
Bonelli L, Puntoni M, Gatteschi B, et al. Antioxidant supplement and long-term reduction of recurrent adenomas of the large bowel. A double-blind randomized trial. J Gastroenterol 2013;48(6):698-705. View abstract.
Bonham M, O'Connor JM, Alexander HD, et al. Zinc supplementation has no effect on circulating levels of peripheral blood leucocytes and lymphocyte subsets in healthy adult men. Br J Nutr 2003;89:695-703.. View abstract.
Borroni G, Brazzelli V, Vignati G, et al. Bullous lesions in acrodermatitis enteropathica. Histopathologic findings regarding two patients. Am J Dermatopathol 1992;14:304-9. View abstract.
Botash AS, Nasca J, Dubowy R, et al. Zinc-induced copper deficiency in an infant. Am J Dis Child 1992;146:709-11. View abstract.
Brewer GJ, Dick RD, Johnson VD, et al. Treatment of Wilson's disease with zinc: XV long-term follow-up studies. J Lab Clin Med 1998;132:264-78. View abstract.
Brewer GJ, Johnson V, Kaplan J. Treatment of Wilson's disease with zinc: XIV. Studies of the effect of zinc on lymphocyte function. J Lab Clin Med 1997;129:649-52. View abstract.
Brewer GJ, Yuzbasiyan-Gurkan V, Johnson V, et al. Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents. J Am Coll Nutr 1993;12:26-30. View abstract.
Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Dermatol 1981;104:191-4. View abstract.
Brook AC, Johnston DG, Ward MK, et al. Absence of a therapeutic effect of zinc in the sexual dysfunction of haemodialysed patients Lancet 1980;2:618-20. View abstract.
Brooks WA, Yunus M, Santosham M, et al. Zinc for severe pneumonia in very young children: double-blind placebo-controlled trial. Lancet 2004;363:1683-8. View abstract.
Broun ER, Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3. View abstract.
Burd GD. Morphological study of the effects of intranasal zinc sulfate irrigation on the mouse olfactory epithelium and olfactory bulb. Microsc Res Tech 1993;24:195-213. View abstract.
Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
Burrows NP, Turnbull AJ, Punchard NA, et al. A trial of oral zinc supplementation in psoriasis. Cutis 1994;54:117-8. View abstract.
Butterworth CE, Hatch K, Cole P, et al. Zinc concentration in plasma and erythrocytes of subjects receiving folic acid supplementation. Am J Clin Nutr 1988;47:484-6. View abstract.
Camacho FM, Garcia-Hernandez MJ. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. Pediatr Dermatol 1999;16:336-8. View abstract.
Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. View abstract.
Canatan D, Temimhan N, Dincer N, et al. Continuous desferrioxamine infusion by an infusor in thalassemia major. Acta Paediatrica 1999;88:550-2. View abstract.
Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50. View abstract.
Capdor J, Foster M, Petocz P, Samman S. Zinc and glycemic control: a meta-analysis of randomised placebo controlled supplementation trials in humans. J Trace Elem Med Biol. 2013 Apr;27(2):137-42. View abstract.
Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. View abstract.
Chavez-Tapia NC, Cesar-Arce A, Barrientos-Gutiérrez T, Villegas-López FA, Méndez-Sanchez N, Uribe M. A systematic review and meta-analysis of the use of oral zinc in the treatment of hepatic encephalopathy. Nutr J. 2013 Jun 6;12:74. View abstract.
Chew EY, Clemons TE, Agrón E, Sperduto RD, Sangiovanni JP, Kurinij N, Davis MD; Age-Related Eye Disease Study Research Group. Long-term effects of vitamins C and E, ß-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology. 2013 Aug;120(8):1604-11.e4. View abstract.
Chew EY1, Klein ML2, Clemons TE3, Agrón E4, Abecasis GR5. Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test? Ophthalmology. 2015 Jan;122(1):212-5. View abstract.
Chia SE, Ong CN, Chua LH, et al. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Androl 2000;21:53-7. View abstract.
Chilvers DC, Jones MM, Selby PL, et al. Effects of oral ethinyl oestradiol and norethisterone on plasma copper and zinc complexes in post-menopausal women. Hormone Metab Res 1985;17:532-5. View abstract.
Christian P, Khatry SK, Yamini S, et al. Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. Am J Clin Nutr 2001;73:1045-51. View abstract.
Clemmensen OJ, Siggaard-Andersen J, Worm AM, et al. Psoriatic arthritis treated with oral zinc sulphate. Br J Dermatol 1980;103:411-5. View abstract.
Cohanim M, Yendt ER. The effects of thiazides on serum and urinary zinc in patients with renal calculi. Johns Hopkins Med J 1975;136:137-44. View abstract.
Consolo LZ, Melnikov P, Cônsolo FZ, Nascimento VA, Pontes JC. Zinc supplementation in children and adolescents with acute leukemia. Eur J Clin Nutr. 2013 Oct;67(10):1056-9. View abstract.
Cossack, Z. T. and van den Hamer, C. J. Kinetics of copper absorption in zinc-overload states and following the withdrawal of zinc supplement: the role of endogenous zinc status. J Pediatr Gastroenterol.Nutr 1987;6(2):296-301. View abstract.
Crofton RW, Gvozdanovic D, Gvozdanovic S, et al. Inorganic zinc and the intestinal absorption of ferrous iron. Am J Clin Nutr 1989;50:141-4.. View abstract.
Crown LA, May JA. Zinc toxicity: denture adhesives, bone marrow failure and polyneuropathy. Tenn Med. 2012 Feb;105(2):39-40, 42. View abstract.
Cunliffe WJ, Burke B, Dodman B, Gould DJ. A double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment of acne vulgaris. Br J Dermatol 1979;101:321-5. View abstract.
Cunningham JJ, Fu A, Mearkle PL, Brown RG. Hyperzincuria in individuals with insulin-dependent diabetes mellitus: concurrent zinc status and the effect of high-dose zinc supplementation. Metabolism 1994;43:1558-62. View abstract.
Dadamio J, Van Tournout M, Teughels W, Dekeyser C, Coucke W, Quirynen M. Efficacy of different mouthrinse formulations in reducing oral malodour: a randomized clinical trial. J Clin Periodontol. 2013 May;40(5):505-13. View abstract.
David TJ, Wells FE, Sharpe TC, et al. Serum levels of trace metals in children with atopic eczema. Br J Dermatol 1990;122:485-9. View abstract.
Davidsson L, Almgren A, Sandstrom B, Hurrell RF. Zinc absorption in adult humans: the effect of iron fortification. Br J Nutr 1995;74:417-25.. View abstract.
De Palma P, Franco F, Bragliani G, et al. The incidence of optic neuropathy in 84 patients treated with ethambutol. Metab Pediatr Syst Ophthalmol 1989;12:80-2. View abstract.
DeCook CA, Hirsch AR. Anosmia due to inhalational zinc: a case report (abstract). Chem Senses 2000;25:659.
Desbiens NA. Lessons learned from attempts to establish the blind in placebo-controlled trials of zinc for the common cold. Ann Intern Med 2000;133:302-3. View abstract.
Devereux G, Turner SW, Craig LC, et al. Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med 2006;174:499-507. View abstract.
Ding Y, Jia YY, Li F, et al. The effect of staggered administration of zinc sulfate on the pharmacokinetics of oral cephalexin. Br J Clin Pharmacol. 2012 Mar;73(3):422-7. View abstract.
Dixon JS, Bird HA, Martin MF, et al. Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs. Int J Clin Pharmacol Res 1985;5:25-33. View abstract.
Donangelo CM, Woodhouse LR, King SM, et al. Supplemental zinc lowers measures of iron status in young women with low iron reserves. J Nutr 2002;132:1860-4.. View abstract.
Dooren JC. FDA warns against use of Zicam. The Wall Street Journal, June 16, 2009. Available at: http://online.wsj.com/article/SB124516778692319231.html#mod=djemHL?mg=com-wsj (Accessed 16 June 2009).
Douglas RM, Miles HB, Moore BW, et al. Failure of effervescent zinc acetate lozenges to alter the course of upper respiratory tract infections in Australian adults. Antimicrob Agents Chemother 1987;31:1263-5. View abstract.
Doz F, Berens ME, Deschepper CF, et al. Experimental basis for increasing the therapeutic index of cis-diamminedicarboxylatocyclobutaneplatinum(II) in brain tumor therapy by a high-zinc diet. Cancer Chemother Pharmacol 1992;29:219-26. View abstract.
Dreno B, Amblard P, Agache P, et al. Low doses of zinc gluconate for inflammatory acne. Acta Derm Venereol 1989;69:541-3. View abstract.
Dreno B, Trossaert M, Boiteau HL, Litoux P. Zinc salts effects on granulocyte zinc concentration and chemotaxis in acne patients. Acta Derm Venereol 1992;72:250-2. View abstract.
Dronfield MW, Malone JD, Langman MJ. Zinc in ulcerative colitis: a therapeutic trial and report on plasma levels. Gut 1977;18:33-6. View abstract.
Ducray A, Bondier JR, Michel G, et al. Recovery following peripheral destruction of olfactory neurons in young and adult mice. Eur J Neurosci 2002;15:1907-17. View abstract.
Duisterwinkel FJ, Wolthers BG, Koopman BJ, et al. Bioavailability of orally administered zinc, using Taurizine. Pharm Weekbl Sci 1986;8:85-8. View abstract.
Ead RD. Oral zinc sulphate in alopacia areata- a double-blind trial. Br J Dermatol 1981;104:483-4. View abstract.
Eby GA, Davis DR, Halcomb WW. Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study. Antimicrob Agents Chemother 1984;25:20-4. View abstract.
Eby GA, Halcomb WW. Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols. Med Hypotheses 1985;17:157-65. View abstract.
Eby GA. Zinc ion availability--the determinant of efficacy in zinc lozenge treatment of common colds. J Antimicrob Chemother 1997;40:483-93. View abstract.
Ellul-Micallef R, Galdes A, Fenech FF. Serum zinc levels in corticosteroid-treated asthmatic patients. Postgrad Med J 1976;52:148-50. View abstract.
Ewing CI, Gibbs AC, Ashcroft C, David TJ. Failure of oral zinc supplementation in atopic eczema. Eur J Clin Nutr 1991;45:507-10. View abstract.
Farr BM, Conner EM, Betts RF, et al. Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds. Antimicrob Agents Chemother 1987;31:1183-7. View abstract.
Faruque AS, Mahalanabis D, Haque SS, et al. Double-blind, randomized, controlled trial of zinc or vitamin A supplementation in young children with acute diarrhea. Acta Paediatr 1999;88:154-60. View abstract.
Fatemi SH, Calabrese JR. Treatment of valproate-induced alopecia (letter). Ann Pharmacother 1995;29;1302. View abstract.
Faure P, Benhamou PY, Perard A, et al. Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation. Eur J Clin Nutr 1995;49:282-8. View abstract.
Fawzi WW, Villamor E, Msamanga GI, et al. Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania. Am J Clin Nutr 2005;81:161-7. View abstract.
Feucht CL, Allen BS, Chalker DK, et al. Topical erythromycin with zinc in acne. A double-blind controlled study. J Am Acad Dermatol 1980;3:483-91. View abstract.
Fleet JC, Turnbull AJ, Bourcier M, Wood RJ. Vitamin D-sensitive and quinacrine-sensitive zinc transport in human intestinal cell line Caco-2. Am J Physiol 1993;264:G1037-45. View abstract.
Flynn A, Pories WJ, Strain WH, et al. Rapid serum zinc depletion associated with corticosteroid therapy. Lancet 1971;2:1169-72. View abstract.
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press, 1999. Available at: http://books.nap.edu/books/0309063507/html/index.html.
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002. Available at: www.nap.edu/books/0309072794/html/.
Fortes C, Forastiere F, Agabiti N, et al. The effect of zinc and vitamin A supplementation on immune response in an older population. J Am Geriatr Soc 1998;46:19-26. View abstract.
Fosmire GJ. Zinc toxicity. Am J Clin Nutr 1990;51:225-7. View abstract.
Freake HC, Govoni KE, Guda K, et al. Actions and interactions of thyroid hormone and zinc status in growing rats. J Nutr 2001;4:1135-41.. View abstract.
Freeland-Graves JH, Lin PH. Plasma uptake of manganese as affected by oral loads of manganese, calcium, milk, phosphorus, copper, and zinc. J Am Coll Nutr 1991;10:38-43. View abstract.
Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;2:793-6. View abstract.
Fuller NJ, Bates CJ, Evans PH, Lucas A. High folate intakes related to zinc status in preterm infants. Eur J Pediatr 1992;151:51-3. View abstract.
Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP. Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2013 Oct;98(4):960-71. View abstract.
Fuse H, Kazama T, Ohta S, Fujiuchi Y. Relationship between zinc concentrations in seminal plasma and various sperm parameters. Int Urol Nephrol 1999;31:401-8. View abstract.
Garcia-Plaza A, Arenas JI, Belda O, Diago A, et al. [A multicenter, clinical trial. Zinc acexamate vs famotidine in the treatment of acute duodenal ulcer. Study group of zinc acexamate]. Rev Esp Enferm Dig 1996;88:757-62. View abstract.
George J, Bhatia VN, Balakrishnan S, Ramu G. Serum zinc/copper ratio in subtypes of leprosy and effect of oral zinc therapy on reactional states. Int J Lepr Other Mycobact Dis 1991;59:20-4. View abstract.
Gibson RS, Yeudall F, Drost N, et al. Dietary interventions to prevent zinc deficiency. Am J Clin Nutr 1998;68:484s-7s. View abstract.
Gibson RS. A historical review of progress in the assessment of dietary zinc intake as an indicator of population zinc status. Adv Nutr. 2012 Nov 1;3(6):772-82. View abstract.
Girodon F, Galan P, Monget AL, et al. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized, controlled trial. MIN. VIT. AOX. geriatric network. Arch Intern Med 1999;159:748-54. View abstract.
Girodon F, Lombard M, Galan P, et al. Effect of micronutrient supplementation on infection in institutionalized elderly subjects: a controlled trial. Ann Nutr Metab 1997;41:98-107. View abstract.
GlaxoSmithKline Consumer Advisory. GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Super Polygrip Original, Ultra Fresh and Extra Care. February 18, 2010. Available at: www.gsk.com/media/consumer-advisories/US.pdf.
Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Altern Ther Health Med 2001;7:49-56. View abstract.
Godfrey JC, Conant Sloane B, Smith DS, et al. Zinc gluconate and the common cold: a controlled clinical study. J Int Med Res 1992;20:234-6. View abstract.
Gogia S, Sachdev HS. Zinc supplementation for mental and motor development in children. Cochrane Database Syst Rev. 2012 Dec 12;12:CD007991. View abstract.
Goldenberg RL, Tamura T, Neggers Y, et al. The effect of zinc supplementation on pregnancy outcome. JAMA 1995;274:463-8. View abstract.
Goldiner WH, Hamilton BP, Hyman PD, Russell RM. Effect of the administration of zinc sulfate on hypogonadism and impotence in patients with chronic stable hepatic cirrhosis. J Am Coll Nutr 1983;2:157-62. View abstract.
Golik A, Modai D, Averbukh Z, et al. Zinc metabolism in patients treated with captopril versus enalapril. Metabolism 1990;39:665-7. View abstract.
Golik A, Modai D, Weissgarten J, et al. Hydrochlorothiazide-amiloride causes excessive urinary zinc excretion. Clin Pharmacol Ther 1987;42:42-4. View abstract.
Golik A, Zaidenstein R, Dishi V, et al. Effects of captopril and enalapril on zinc metabolism in hypertensive patients. J Am Coll Nutr 1998;17:75-8. View abstract.
Goodarzi D, Cyrus A, Baghinia MR, Kazemifar AM, Shirincar M. The efficacy of zinc for treatment of chronic prostatitis. Acta Med Indones. 2013 Oct;45(4):259-64. View abstract.
Goransson K, Liden S, Odsell L. Oral zinc in acne vulgaris: a clinical and methodological study. Acta Derm Venereol 1978;58:443-8. View abstract.
Grahn BH, Paterson PG, Gottschall-Pass KT, Zhang Z. Zinc and the eye. J Am Coll Nutr 2001;20:106-18. View abstract.
Grazioso CF, Isalgue M, de Ramirez I, et al. The effect of zinc supplementation on parasitic reinfestation of Guatemalan schoolchildren. Am J Clin Nutr 1993;57:673-8. View abstract.
Green S. Chelation therapy: unproven claims and unsound theories. Quackwatch 2000. Available at: http://www.quackwatch.org (Accessed 17 November 2000).
Greenberg JE, Lynn M, Kirsner RS, et al. Mucocutaneous pigmented macule as a result of zinc deposition. J Cutan Pathol 2002;29:613-5. View abstract.
Guide to Clinical Preventive Services. 2nd ed. Natl Institute of Health, 1996. Available at: http://hstat2.nlm.nih.gov/download/409812772438.html.
Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents: Drug Interactions between Integrase Inhibitors and Other Drugs. AIDSinfo. July 14, 2016. Available at: https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv-guidelines/287/insti-drug-interactions. (Accessed: 4/12/2017).
Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty Acids 1994;51:311-6. View abstract.
Guldager B, Jorgensen PJ, Grandjean P. Metal excretion and magnesium retention in patients with intermittent claudication treated with intravenous disodium EDTA. Clin Chem 1996;42:1938-42. View abstract.
Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatology Res Pract. 2014;2014.
Gupta VL, Chaubey BS. Efficacy of zinc therapy in prevention of crisis in sickle cell anemia: a double blind, randomized controlled clinical trial. J Assoc Physicians India 1995;43:467-9. View abstract.
Habbema L, Koopmans B, Menke HE, et al. A 4% erythromycin and zinc combination (Zineryt) versus 2% erythromycin (Eryderm) in acne vulgaris: a randomized, double-blind comparative study. Br J Dermatol 1989;121:497-502. View abstract.
Hahn CJ, Evans GW. Absorption of trace metals in the zinc-deficient rat. Am J Physiol 1975;228:1020-3. View abstract.
Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
Hasinoff BB. Chemistry of dexrazoxane and analogues. Semin Oncol 1998;24:3-9. View abstract.
Health Canada / GlaxoSmithKline Consumer Healthcare. Association of long-term, excessive use of zinc-containing Poli-Grip products with myeloneuropathy and blood dyscrasias. February 18, 2010. Available at: http://hc-sc.gc.ca/dhp-mps/alt_formats/pdf/medeff/advisories-avis/prof/2010/poligrip_hpc-cps-eng.pdf.
Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
Hemilä H, Petrus EJ, Fitzgerald JT, Prasad A. Zinc acetate lozenges for treating the common cold: an individual patient data meta-analysis. Br J Clin Pharmacol. 2016 Jul 5. View abstract.
Henderson LM, Brewer GJ, Dressman JB, et al. Effect of intragastric pH on the absorption of oral zinc acetate and zinc oxide in young healthy volunteers. JPEN J Parenter Enteral Nutr 1995;19:393-7. View abstract.
Henkel R, Bittner J, Weber R, et al. Relevance of zinc in human sperm flagella and its relation to motility. Fertil Steril 1999;71:1138-43. View abstract.
Henkin RI, Foster DM, Aamodt RL, Berman M. Zinc metabolism in adrenal cortical insufficiency: effects of carbohydrate-active steroids. Metabolism 1984;33:491-501. View abstract.
Henkin RI, Martin BM, Agarwal RP. Decreased parotid saliva gustin/carbonic anhydrase VI secretion: an enzyme disorder manifested by gustatory and olfactory dysfunction. Am J Med Sci 1999;318:380-91. View abstract.
Henkin RI, Martin BM, Agarwal RP. Efficacy of exogenous oral zinc in treatment of patients with carbonic anhydrase VI deficiency. Am J Med Sci 1999;318:392-405. View abstract.
Henkin RI, Schecter PJ, Friedewald WT, et al. A double-blind study of the effects of zinc sulfate on taste and smell dysfunction. Am J Med Sci 1976;272:285-99. View abstract.
Heyneman CA. Zinc deficiency and taste disorders. Ann Pharmacother 1996;30:186-7. View abstract.
Higashi A, Ikeda T, Matsukura M, Matsuda I. Serum zinc and vitamin E concentrations in handicapped children treated with anticonvulsants. Devel Pharmacol Ther 1982;5:109-13. View abstract.
Higgins TL, Murray M, Kett DH, et al. Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients. Intensive Care Med 2000;26:s413-21. View abstract.
Hillstrom L, Pettersson L, Hellbe L, et al. Comparison of oral treatment with zinc sulphate and placebo in acne vulgaris. Br J Dermatol 1977;97:681-4. View abstract.
Hinks LJ, Clayton BE, Lloyd RS. Zinc and copper concentrations in leukocytes and erythrocytes in healthy adults and the effect of oral contraceptives. J Clin Pathol 1983;36:1016-21. View abstract.
Hirt M, Nobel S, Barron E. Zinc nasal gel for the treatment of common cold symptoms: A double-blind, placebo-controlled trial. Ear Nose Throat J 2000;79:778-82.. View abstract.
Hoogenraad TU, Van Hattum J, Van den Hamer CJ. Management of Wilson's disease with zinc sulphate. Experience in a series of 27 patients. J Neurol Sci 1987;77:137-46. View abstract.
Houang ET, Ahmet Z, Lawrence AG. Successful treatment of four patients with recalcitrant vaginal trichomoniasis with a combination of zinc sulfate douche and metronidazole therapy. Sex Transm Dis 1997;24:116-9. View abstract.
Huang X, Cuajungco MP, Atwood CS, et al. Alzheimer's disease, beta-amyloid protein and zinc. J Nutr 2000;130:1488S-92S. View abstract.
Hunt CD, Johnson PE, Herbel J, Mullen LK. Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men. Am J Clin Nutr 1992;56:148-57. View abstract.
Hunt JR. Moving toward a plant-based diet; are iron and zinc at risk? Nutr Rev 2002;60:127-34. View abstract.
Hurd RW, Van Rinsvelt HA, Wilder BJ, et al. Selenium, zinc, and copper changes with valproic acid: possible relation to drug side effects. Neurology 1984;34:1393-5. View abstract.
Hurd RW, Wilder BJ, Van Rinsvelt HA. Valproate, birth defects, and zinc (letter). Lancet 1983;1:181. View abstract.
Hurrell RF. Influence of vegetable protein sources on trace element and mineral bioavailability. J Nutr 2003;133:2973s-7s. View abstract.
Hyun TH, Barrett-Connor E, Milne DB. Zinc intakes and plasma concentrations in men with osteoporosis: the Rancho Bernardo Study. Am J Clin Nutr 2004;80:715-21. View abstract.
Ilhan A, Uz E, Kali S, et al. Serum and hair trace element levels in patients with epilepsy and healthy subjects: does the antiepileptic therapy affect the element concentrations of hair? Eur J Neurol 1999;6:705-9. View abstract.
Intorre, F., Polito, A., Andriollo-Sanchez, M., Azzini, E., Raguzzini, A., Toti, E., Zaccaria, M., Catasta, G., Meunier, N., Ducros, V., O'Connor, J. M., Coudray, C., Roussel, A. M., and Maiani, G. Effect of zinc supplementation on vitamin status of middle-aged and older European adults: the ZENITH study. Eur.J Clin Nutr 2008;62(10):1215-1223. View abstract.
Jackson JL, Lesho E, Peterson C. Zinc and the common cold: a meta-analysis revisited. J Nutr 2000;130:1512S-5S. View abstract.
Jafek BW, Linschoten M, Murrow BW. Zicam Induced Anosmia. American Rhinologic Society 49th Annual Fall Scientific Meeting abstract. Orlando, Florida. September 20, 2003. http://app.american-rhinologic.org/programs/2003ARSFallProgram071503.pdf (Accessed 24 November 2003).
Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. View abstract.
Jimenez E, Bosch F, Galmes JL, Banos JE. Meta-analysis of efficacy of zinc acexamate in peptic ulcer. Digestion 1992;51:18-26. View abstract.
Kadhim, HM, Ismail, SH, Hussein, KI, et al. Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with metformin. J Pineal Res 2006;41:189-93. View abstract.
Kaji M, Ito M, Okuno T, et al. Serum copper and zinc levels in epileptic children with valproate treatment. Epilepsia 1992;33:555-7. View abstract.
Kakar F, Henderson MM. Potential toxic side effects of folic acid (letter). J Natl Cancer Inst 1985;74:263. View abstract.
Katz RL, Keen CL, Litt IF, et al. Zinc deficiency in anorexia nervosa. J Adolesc Health Care 1987;8:400-6. View abstract.
Kauwell GPA, Baily LB, Gregory JF, et al. Zinc status is not adversely affected by folic acid supplementation and zinc intake does not impair folate utilization in human subjects. J Nutr 1995;125:66-72. View abstract.
Keating JN, Wada L, Stokstad ELR, King JC. Folic acid: effect on zinc absorption in humans and in the rat. Am J Clin Nutr 1987;46:835-9. View abstract.
Kelly P, Musonda R, Kafwembe E, et al. Micronutrient supplementation in the AIDS diarrhea-wasting syndrome in Zambia: a randomized controlled trial. AIDS 1999;13:495-500. View abstract.
Khanna VJ, Shieh S, Benjamin J, et al. Necrolytic acral erythema associated with hepatitis C effective treatment with interferon alfa and zinc. Arch Dermatol 2000;136:755-7. View abstract.
Khedun SM, Naicker T, Maharaj B. Zinc, hydrochlorothiazide and sexual dysfunction. Cent Afr J Med 1995;41:312-5. View abstract.
Kimmel, P. Zinc and chronic renal disease. Seminar in Dialysis 1989;2(4):253-259.
King AB, Schwartz R. Effects of the antituberculous drug ethambutol on zinc absorption, turnover and distribution in rats fed diets marginal and adequate in zinc. J Nutr 1987;117:704-8. View abstract.
King JC. Do women using oral contraceptive agents require extra zinc? J Nutr 1987;117:217-9. View abstract.
King JC. Enhanced zinc utilization during lactation may reduce maternal and infant zinc depletion. Am J Clin Nutr 2002;75:2-3. View abstract.
Kingberg WG, Prasad AS, Oberleas D. Zinc deficiency following penicillamine therapy. In: Prasad AS (ed). Trace Elements in Human Health and Disease. Vol.I, Zinc and Copper. Academic Press, New York, 1976. pp51-65.
Kneist W, Hempel B, Borelli S. [Clinical, double-blind trial of topical zinc sulfate for herpes labialis recidivans]. Arzneimittelforschung 1995;45:624-6. View abstract.
Koletzko B, Bretschneider A, Bremer HJ. Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation. Eur J Pediatr 1985;143:310-4. View abstract.
Kondo Y, Yamagata K, Satoh M, et al. Optimal administration schedule of cisplatin for bladder tumor with minimal induction of metallothionein. J Urol 2003;170:2467-70. View abstract.
Krone CA, Wyse EJ, Ely JT. Cadmium in zinc-containing mineral supplements. Int J Food Sci Nutr 2001;52:379-82.. View abstract.
Kugelmas M. Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. J Am Coll Nutr 2000;19:13-5. View abstract.
Kumar A, Bagri NK, Basu S, Asthana RK. Zinc supplementation for neonatal hyperbilirubinemia: a randomized controlled trial. Indian Pediatr. 2014 May;51(5):375-8. View abstract.
Kuo SM, Leavitt PS, Lin CP. Dietary flavonoids interact with trace metals and affect metallothionein level in human intestinal cells. Biol Trace Elem Res 1998;62:135-53. View abstract.
Lagiou P, Wuu J, Trichopoulou A, et al. Diet and benign prostatic hyperplasia: a study in Greece. Urology 1999;54:284-90. View abstract.
Lalles J-P.Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet. Nutr Rev. 2010;68(6):323-332. View abstract.
Lawson KA, Wright ME, Subar A, et al. Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. J Natl Cancer Inst 2007;99:754-64. View abstract.
Leary WP, Reyes AJ, Van der Byl K. Urinary magnesium and zinc excretion after two different single doses of amiloride in healthy adults. Curr Ther Res 1983;34:205-16.
Leibovici V, Statter M, Weinrauch L, et al. Effect of zinc therapy on neutrophil chemotaxis in psoriasis. Isr J Med Sci 1990;26:306-9. View abstract.
Leibovitz B, Siegel BV. Ascorbic acid and the immune response. Adv Exp Med Biol 1981;135:1-25. View abstract.
Leitzmann MF, Stampfer MJ, Wu K, et al. Zinc supplement use and risk of prostate cancer. J Natl Cancer Inst 2003;95:1004-7.. View abstract.
Leonard MB, Zemel BS, Kawchak DA, et al. Plasma zinc status, growth, and maturation in children with sickle cell disease. J Pediatr 1998;132:467-71. View abstract.
Lerman-Sagie T, Statter M, Szabo G, Lerman P. Effect of valproic acid therapy on zinc metabolism in children with primary epilepsy. Clin Neuropharmacol 1987;10:80-6. View abstract.
Lewis-Jones MS, Evans S, Culshaw MA. Cutaneous manifestations of zinc deficiency during treatment with anticonvulsants. BMJ 1985;290:603-4. View abstract.
Li P, Xu J, Shi Y, Ye Y, Chen K, Yang J, Wu Y. Association between zinc intake and risk of digestive tract cancers: a systematic review and meta-analysis. Clin Nutr. 2014 Jun;33(3):415-20. View abstract.
Licastro F, Chiricolo M, Mocchegiani E, et al. Oral zinc supplementation in Down's syndrome subjects decreased infections and normalized some humoral and cellular immune parameters. J Intellect Disabil Res 1994;38:149-62. View abstract.
Liu CS, Wu HM, Kao SH, Wei YH. Serum trace elements, glutathione, copper/zinc superoxide dismutase, and lipid peroxidation in epileptic patients with phenytoin or carbamazepine monotherapy. Clin Neuropharmacol 1998;21:62. View abstract.
Liukko P, Erkkola R, Pakarinen P, et al. Trace elements during 2 years' oral contraception with low-estrogen preparations. Gynecol Obstet Invest 1988;25:113-7. View abstract.
Lomaestro BM, Bailie GR. Absorption interactions with fluoroquinolones. 1995 update. Drug Saf 1995;12:314-33. View abstract.
Lonnerdal B, Cederblad A, Davidsson L, Sandstrom B. The effect of individual components of soy formula and cows' milk formula on zinc bioavailability. Am J Clin Nutr 1984;40:1064-70. View abstract.
Lonnerdal B. Dietary factors influencing zinc absorption. J Nutr 2000;130:1378s-83s. View abstract.
Lopez de Romana D, Lonnerdal B, Brown KH. Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide. Am J Clin Nutr 2003;78:279-83.. View abstract.
Lovell MA, Robertson JD, Teesdale WJ, et al. Copper, iron and zinc in Alzheimer's disease senile plaques. J Neurol Sci 1998;158:47-52. View abstract.
Lovell MA, Xie C, Markesbery WR. Protection against amyloid beta peptide toxicity by zinc. Brain Res 1999;823:88-95. View abstract.
Lyckholm L, Heddinger SP, Parker G, Coyne PJ, Ramakrishnan V, Smith TJ, Henkin RI. A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders. J Pain Palliat Care Pharmacother. 2012 Jun;26(2):111-4. View abstract.
Macknin ML, Piedmonte M, Calendine C, et al. Zinc gluconate lozenges for treating the common cold in children: a randomized, controlled trial. JAMA 1998;279:1962-7. View abstract.
Maes M, De Vos N, Demedts P, et al. Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 1999;56:189-94. View abstract.
Mahajan PM, Jadhav VH, Patki AH, et al. Oral zinc therapy in recurrent erythema nodosum leprosum: a clinical study. Indian J Lepr 1994;66:51-7. View abstract.
Mahajan SK, Abbasi AA, Prasad AS, et al. Effect of oral zinc therapy on gonadal function in hemodialysis patients. A double-blind study. Ann Intern Med 1982;97:357-61. View abstract.
Mahajan SK, Prasad AS, Lambujon J, et al. Improvement of uremic hypogeusia by zinc: a double-blind study. Am J Clin Nutr 1980;33:1517-21. View abstract.
Mahalanabis D, Chowdhury A, Jana S, et al. Zinc supplementation as adjunct therapy in children with measles accompanies by pneumonia: a double-blind, randomized controlled trial. Am J Clin Nutr 2002;76:604-7.. View abstract.
Mansouri A, Hadjibabaie M, Iravani M, Shamshiri AR, Hayatshahi A, Javadi MR, Khoee SH, Alimoghaddam K, Ghavamzadeh A. The effect of zinc sulfate in the prevention of high-dose chemotherapy-induced mucositis: a double-blind, randomized, placebo-controlled study. Hematol Oncol. 2012 Mar;30(1):22-6. View abstract.
Mares-Perlman JA, Klein R, Klein BE, et al. Association of zinc and antioxidant nutrients with age-related maculopathy. Arch Ophthalmol 1996;114:991-7. View abstract.
Marshall I. Zinc for the common cold. Cochrane Database Syst Rev 2000;(2):CD001364. View abstract.
Mathur NK, Bumb RA, Mangal HN, Sharma ML. Oral zinc as an adjunct to dapsone in lepromatous leprosy. Int J Lepr Other Mycobact Dis 1984;52:331-8. View abstract.
Mathur NK, Bumb RA, Mangal HN. Oral zinc in recurrent Erythema Nodosum Leprosum reaction. Lepr India 1983;55:547-52. View abstract.
Mayer AD, Rosenblatt JS. Peripheral olfactory deafferentation of the primary olfactory system in rats using ZnSO4 nasal spray with special reference to maternal behavior. Physiol Behav 1993;53:587-92. View abstract.
McBride K, Slotnick B, Margolis FL. Does intranasal application of zinc sulfate produce anosmia in the mouse? An olfactometric and anatomical study. Chem Senses 2003;28:659-70. View abstract.
McCall JT, Goldstein NP, Randall RV, Gross JB. Comparative metabolism of copper and zinc in patients with Wilson's Disease (hepatollenticular degeneration). Am J Med Sci 1967;254:13-23. View abstract.
McElroy BH, Miller SP. Effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) against the common cold in school-aged subjects: a retrospective chart review. Am J Ther 2002;9:472-5.. View abstract.
McKenna AA, Ilich JZ, Andon MB, et al. Zinc balance in adolescent females. Am J Clin Nutr 1997;65:1460-4. View abstract.
McNeil JJ, Anderson A, Christophidis N, et al. Taste loss associated with oral captopril treatment. BMJ 1979;448:1555-6. View abstract.
Merchant HW, Gangarosa LP, Glassman AB, Sobel RE. Zinc sulfate supplementation for treatment of recurring oral ulcers. South Med J 1977;70:559-61. View abstract.
Mery C, Delrieu F, Ghozlan R, et al. Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc. Scand J Rheumatol 1976;5:241-7. View abstract.
Meyer F, Galan P, Douville P, et al. Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial. Int J Cancer 2005;116:182-6. View abstract.
Meynadier J. Efficacy and safety study of two zinc gluconate regimens in the treatment of inflammatory acne. Eur J Dermatol 2000 May;10:269-73. View abstract.
Michaelsson G, Juhlin L, Ljunghall K. A double-blind study of the effect of zinc and oxytetracycline in acne vulgaris. Br J Dermatol 1977;97:561-6. View abstract.
Michaelsson G, Juhlin L, Vahlquist A. Effects of oral zinc and vitamin A in acne. Arch Dermatol 1977;113:31-6. View abstract.
Michaelsson G, Ljunghall K. Patients with dermatitis herpetiformis, acne, psoriasis and Darier's disease have low epidermal zinc concentrations. Acta Derm Venereol 1990;70:304-8. View abstract.
Michaelsson G, Vahlquist A, Juhlin L. Serum zinc and retinol-binding protein in acne. Br J Dermatol 1977;96:283-6. View abstract.
Mills CF. Dietary interactions involving the trace elements. Ann Rev Nutr 1985;5:173-93. View abstract.
Milne DB, Canfield WK, Mahalko JR, Sandstead HH. Effect of oral folic acid supplements on zinc, copper, and iron absorption and excretion. Am J Clin Nutr 1984;39:535-9. View abstract.
Misbahuddin M, Islam A Z, Khandker S, et al. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study. Clin Toxicol (Phila) 2006;44:135-41. View abstract.
Mocchegiani E, Veccia S, Ancarani F, et al. Benefit of oral zinc supplementation as an adjunct to zidovudine (AZT) therapy against opportunistic infections in AIDS. Int J Immunopharmacol 1995;17:719-27. View abstract.
Mohan H, Verma J, Singh I, et al. Inter-relationship of zinc levels in serum and semen in oligospermic infertile patients and fertile males. Indian J Pathol Microbiol 1997;40:451-5. View abstract.
Moser-Veillon PB. Zinc: consumption patterns and dietary recommendations. J Am Diet Assoc 1990;90:1089-93. View abstract.
Mossad SB, Macknin ML, Medendorp SV, Mason P. Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study. Ann Intern Med 1996;125:81-8. View abstract.
Mossad SB. Effect of zincum gluconicum nasal gel on the duration and symptom severity of the common cold in otherwise healthy adults. QJM 2003;96:35-43. View abstract.
Mostafa WZ, al-Zayer AA. Acrodermatitis enteropathica in Saudi Arabia. Int J Dermatol 1990;29:134-8. View abstract.
Mountokalakis T, Dourakis S, Karatzas N, et al. Zinc deficiency in mild hypertensive patients treated with diuretics. J Hypertens Suppl 1984;2:S571-2. View abstract.
Moyle G, Else L, Jackson A, Back D, Yapa MH, Seymour N, Ringner-Nackter L, Karolia Z, Gazzard B, Boffito M. Coadministration of atazanavir-ritonavir and zinc sulfate: impact on hyperbilirubinemia and pharmacokinetics. Antimicrob Agents Chemother. 2013 Aug;57(8):3640-4. View abstract.
Mulder TP, van der Sluys Veer A, Verspaget HW, et al. Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease. J Gastroenterol Hepatol 1994;9:472-7. View abstract.
Muller O, Becher H, van Zweeden AB, et al. Effect of zinc supplementation on malaria and other causes of morbidity in west African children: randomised double blind placebo controlled trial. BMJ 2001;322:1567. View abstract.
Naber TH, van den Hamer CJ, Baadenhuysen H, Jansen JB. The value of methods to determine zinc deficiency in patients with Crohn's disease. Scand J Gastroenterol 1998;33:514-23. View abstract.
Nagraj SK, Naresh S, Srinivas K, Renjith George P, Shrestha A, Levenson D, Ferraiolo DM. Interventions for the management of taste disturbances. Cochrane Database Syst Rev. 2014 Nov 26;11:CD010470. View abstract.
Najafabadi MM, Faghihi G, Emami A, Monghad M, Moeenzadeh F, Sharif N, Davarpanah Jazi AH. Zinc sulfate for relief of pruritus in patients on maintenance hemodialysis. Ther Apher Dial. 2012 Apr;16(2):142-5. View abstract.
Naveh Y, Schapira D, Ravel Y, et al. Zinc metabolism in rheumatoid arthritis: plasma and urinary zinc and relationship to disease activity. J Rheumatol 1997;24:643-6. View abstract.
Nechifor M, Vaideanu C, Palamaru I, et al. The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia. J Am Coll Nutr 2004;23:549S-51S. View abstract.
Neuvonen PJ. Interactions with the absorption of tetracyclines. Drugs 1976;11:45-54.. View abstract.
Newsome DA, Swartz M, Leone NC, et al. Oral zinc in macular degeneration. Arch Ophthalmol 1988;106:192-8. View abstract.
Nielsen FH, Milne DB. A moderately high intake compared to a low intake of zinc depresses magnesium balance and alters indices of bone turnover in postmenopausal women. Eur J Clin Nutr 2004;58:703-10. View abstract.
Nouri M, Chalian H, Bahman A, et al. Nail molybdenum and zinc contents in populations with low and moderate incidence of esophageal cancer. Arch Iranian Med 2008;11:392-6. View abstract.
O'Brien KO, Zavaleta N, Caulfield LE, et al. Influence of prenatal iron and zinc supplements on supplemental iron absorption, red blood cell iron incorporation, and iron status in pregnant Peruvian women. Am J Clin Nutr 1999;69:509-15.. View abstract.
O'Brien KO, Zavaleta N, Caulfield LE, et al. Prenatal iron supplements impair zinc absorption in pregnant Peruvian women. J Nutr 2000 130:2251-5.. View abstract.
O'Connor DT, Strause L, Saltman P, et al. Serum zinc is unaffected by effective captopril treatment of hypertension. J Clin Hypertens 1987;3:405-8. View abstract.
Oberleas D, Prasad AS. Factors affecting zinc homeostasis. In: Prasad AS (ed). Trace Elements in Human Health and Disease. Vol 1, zinc and copper. Academic Press, New York, 1976.
Omu AE, Dashti H, Al-Othman S. Treatment of asthenozoospermia with zinc sulphate: andrological, immunological and obstetric outcome. Eur J Obstet Gynecol Reprod Biol 1998;79:179-84. View abstract.
Orris L, Shalita AR, Sibulkin D, et al. Oral zinc therapy of acne. Absorption and clinical effect. Arch Dermatol 1978;114:1018-20. View abstract.
OTC Ingredient List. FDA Office of Nonprescription Products. March 2006. Available at: www.fda.gov/cder/Offices/OTC/Ingredient_List_P-Z.pdf.
Ozutemiz AO, Aydin HH, Isler M, et al. Effect of omeprazole on plasma zinc levels after oral zinc administration. Ind J Gastroenterol 2002;21:216-8. View abstract.
Paaske PB, Pedersen CB, Kjems G, Sam IL. Zinc in the management of tinnitus. Placebo-controlled trial. Ann Otol Rhinol Laryngol 1991;100:647-9. View abstract.
Palm R, Hallmans G. Zinc and copper metabolism in phenytoin therapy. Epilepsia 1982;23:453-61. View abstract.
Palomo F, Wantland L, Sanchez A, Volpe AR, McCool J, DeVizio W. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study. Int Dent J. 1994 Feb;44(1 Suppl 1):75-81. View abstract.
Pecoud A, Donzel P, Schelling JL. Effect of foodstuffs on the absorption of zinc sulfate. Clin Pharmacol Ther 1975;17:469-74. View abstract.
Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
Penny ME, Peerson JM, Marin RM, et al. Randomized, community-based trial of the effect of zinc supplementation, with and without other micronutrients, on the duration of persistent childhood diarrhea in Lima, Peru. J Pediatr 1999;135:208-17. View abstract.
Penttila O, Hurme H, Neuvonen PJ. Effect of zinc sulfate on the absorption of tetracycline and doxycycline in man. Eur J Clin Pharmacol 1975;9:131-4. View abstract.
Personal communication: Pantoprazole IV - safety and tolerability of EDTA. Medical Information Department, Wyeth Pharmaceuticals Inc., Philadelphia, PA. February 24, 2005.
Petrus EJ, Lawson KA, Bucci LR, Blum K. Randomized, double-masked, placebo-controlled clinical study of the effectiveness of zinc acetate lozenges on common cold symptoms in allergy-tested subjects. Curr Ther Res 1998;59:595-607.
Pierard-Franchimont C, Goffin V, Visser JN, et al. A double-blind controlled evaluation of the sebosuppressive activity of topical erythromycin-zinc complex. Eur J Clin Pharmacol 1995;49:57-60. View abstract.
Pinedo G, Zarate AJ, Inostroza G, Meneses X, Falloux E, Molina O, Molina ME, Bellolio F, Zúñiga A. New treatment for faecal incontinence using zinc-aluminium ointment: a double-blind randomized trial. Colorectal Dis. 2012 May;14(5):596-8. View abstract.
Pinna A, Corda L, Carta F. Rapid recovery with oral zinc sulphate in deferoxamine-induced presumed optic neuropathy and hearing loss. J Neuroophthalmol 2001;21:32-3. View abstract.
Polenik P. Zinc in etiology of periodontal disease. Med Hypotheses 1993;40:182-5. View abstract.
Polk RE, Healy DP, Sahai J, et al. Effect of ferrous sulfate and multivitamins with zinc on absorption of ciprofloxacin in normal volunteers. Antimicrob Agents Chemother 1989;33:1841-4. View abstract.
Potocnik FC, van Rensburg SJ, Park C, et al. Zinc and platelet membrane microviscosity in Alzheimer's disease. The in vivo effect of zinc on platelet membranes and cognition. S Afr Med J 1997;87:1116-9. View abstract.
Powell-Beard L, Lei KY, Shenker L. Effect of long-term oral contraceptive therapy before pregnancy on maternal and fetal zinc and copper status. Obstet Gynecol 1987;69:26-32. View abstract.
Prasad AS, Beck FW, Kaplan J, et al. Effect of zinc supplementation on incidence of infections and hospital admissions in sickle cell disease (SCD). Am J Hematol 1999;61:194-202. View abstract.
Prasad AS, Fitzgerald JT, Bao B, et al. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 2000;133:245-52. View abstract.
Prasad AS, Oberleas D, Lei KY, et al. Effect of oral contraceptive agents on nutrients: I. Minerals. Am J Clin Nutr 1975;28:377-84. View abstract.
Prasad AS. Zinc and immunity. Mol Cell Biochem 1998;188:63-9. View abstract.
Prasad AS. Zinc deficiency in patients with sickle cell disease. Am J Clin Nutr 2002;75:181-2. View abstract.
Prema K, Ramalakshmi Ba, Babu S. Serum copper and zinc in hormonal contraceptive users. Fertil Steril 1980;33;267-71. View abstract.
Provinciali M, Montenovo A, Di Stefano G, et al. Effect of zinc or zinc plus arginine supplementation on antibody titre and lymphocyte subsets after influenza vaccination in elderly subjects: a randomized controlled trial. Age Ageing 1998;27:715-22. View abstract.
Public Health Advisory. Loss of sense of smell with intranasal cold remedies containing zinc. U.S. Food and Drug Administration, June 16, 2009. Available at: http://www.fda.gov/Drugs/DrugSafety/PublicHealthAdvisories/ucm166059.htm (Accessed 16 June 2009).
Qiao L, Feng Y. Intakes of heme iron and zinc and colorectal cancer incidence: a meta-analysis of prospective studies. Cancer Causes Control. 2013 Jun;24(6):1175-83. View abstract.
Rahman MM, Wahed MA, Fuchs GJ, et al. Synergistic effect of zinc and vitamin A on the biochemical indexes of vitamin A nutrition in children. Am J Clin Nutr 2002;75:92-8. View abstract.
Ramakrishnan U., Nguyen P., Martorell R. Effects of micronutrients on growth of children under 5 y of age: meta-analyses of single and multiple nutrient interventions. Am J Clin Nutr 2009;89(1):191-203. View abstract.
Ranjbar E, Shams J, Sabetkasaei M, M-Shirazi M, Rashidkhani B, Mostafavi A, Bornak E, Nasrollahzadeh J. Effects of zinc supplementation on efficacy of antidepressant therapy, inflammatory cytokines, and brain-derived neurotrophic factor in patients with major depression. Nutr Neurosci. 2014 Feb;17(2):65-71. View abstract.
Rasker JJ, Kardaun SH. Lack of beneficial effect of zinc sulphate in rheumatoid arthritis. Scand J Rheumatol 1982;11:168-70. View abstract.
Rauscher AM, Fairweather-Tait SJ, Wilson PD, et al. Zinc metabolism in non-insulin dependent diabetes mellitus. J Trace Elem Med Biol 1997;11:65-70. View abstract.
Relea P, Revilla M, Ripoll E, et al. Zinc, biochemical markers of nutrition, and type I osteoporosis. Age Ageing 1995;24:303-7. View abstract.
Reyes AJ, Olhaberry JV, Leary WP, et al. Urinary zinc excretion, diuretics, zinc deficiency and some side-effects of diuretics. S Afr Med J 1983;64:936-41. View abstract.
Ripamonti C, Zecca E, Brunelli C, et al. A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation. Cancer 1998;82:1938-45. View abstract.
Rittenhouse T. The management of lower-extremity ulcers with zinc-saline wet dressings versus normal saline wet dressings. Adv Ther 1996;13:88-94. View abstract.
Rodger RS, Sheldon WL, Watson MJ, et al. Zinc deficiency and hyperprolactinaemia are not reversible causes of sexual dysfunction in uraemia. Nephrol Dial Transplant 1989;4:888-92. View abstract.
Rodriguez de la Serna A, Diaz-Rubio M. Multicenter clinical trial of zinc acexamate in the prevention of nonsteroidal antiinflammatory drug induced gastroenteropathy. Spanish Study Group on NSAID Induced Gastroenteropathy Prevention. J Rheumatol 1994;21:927-33. View abstract.
Rossander-Hulten L, Brune M, Sandstrom B, et al. Competitive inhibition of iron absorption by manganese and zinc in humans. Am J Clin Nutr 1991;54:152-6.. View abstract.
Roy SK, Tomkins AM, Akramuzzaman SM, et al. Randomized, controlled trial of zinc supplementation in malnourished Bangladeshi children with acute diarrhea. Arch Dis Child 1997;77:196-200. View abstract.
Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61:621S-4S. View abstract.
Sandstrom B, Almgren A, Kivisto B, Cederblad A. Effect of protein level and protein source on zinc absorption in humans. J Nutr 1989;119:48-53. View abstract.
Sandstrom B, Kivisto B, Cederblad A. Absorption of zinc from soy protein meals in humans. J Nutr 1987;117:321-7. View abstract.
Sayyah M, Olapour A, Saeedabad Ys, Yazdan Parast R, Malayeri A. Evaluation of oral zinc sulfate effect on obsessive-compulsive disorder: a randomized placebo-controlled clinical trial. Nutrition. 2012 Sep;28(9):892-5. View abstract.
Sazawal S, Black RE, Bhan MK, et al. Zinc supplementation in young children with acute diarrhea in India. N Engl J Med 1995;333:839-44. View abstract.
Sazawal S, Black RE, Menon VP, et al. Zinc supplementation in infants born small for gestational age reduces mortality: a prospective, randomized, controlled trial. Pediatrics 2001;108:1280-6. View abstract.
Schachner L, Eaglstein W, Kittles C, Mertz P. Topical erythromycin and zinc therapy for acne. J Am Acad Dermatol 1990;22:253-60. View abstract.
Schaeken MJ, van der Hoeven JS, Saxton CA, Cummins D. The effect of mouthrinses containing zinc and triclosan on plaque accumulation, development of gingivitis and formation of calculus in a 28-week clinical test. J Clin Periodontol 1996;23:465-70. View abstract.
Schiliro G, Russo A, Azzia N, et al. Leukocyte alkaline phosphatase (LAP). A useful marker of zinc status in beta-thalassemic patients. Am J Ped Hematol Oncol 1987;9:149-52. View abstract.
Science M, Johnstone J, Roth DE, et al. Zinc for the treatment of the common cold: a systematic review and meta-analysis of randomized controlled trials. CMAJ 2012;184:E551-61. View abstract.
Scott R, Ferrie B, McLelland A, Fell GS. The effect of steroid therapy on serum trace metal levels in sub-fertile males. Urol Res 1984;12:213-5. View abstract.
Seelig MS. Auto-immune complications of D-penicillamine - A possible result of zinc and magnesium depletion and of pyridoxine inactivation. J Am Coll Nutr 1982;1:207-14. View abstract.
Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
Serfaty-Lacrosniere C, Wood RJ, Voytko D, et al. Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium, or zinc from food in humans. J Am Coll Nutr 1995;14:364-8. View abstract.
Shah GS, Dutta AK, Shah D, Mishra OP. Role of zinc in severe pneumonia: a randomized double bind placebo controlled study. Ital J Pediatr. 2012 Aug 2;38:36. View abstract.
Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr 1998;68:447S-63S. View abstract.
Sharquie KE, Najim RA, Farjou IB. A comparative controlled trial of intralesionally-administered zinc sulphate, hypertonic sodium chloride and pentavalent antimony compound against acute cutaneous leishmaniasis. Clin Exp Dermatol 1997;22:169-73. View abstract.
Sheqwara J, Alkhatib Y. Sideroblastic anemia secondary to zinc toxicity. Blood. 2013 Jul 18;122(3):311. View abstract.
Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams & Wilkins, 1999.
Sian L, Krebs NF, Westcott JE, et al. Zinc homeostasis during lactation in a population with a low zinc intake. Am J Clin Nutr 2002;75:99-103. View abstract.
Siberry GK, Ruff AJ, Black R. Zinc and human immunodeficiency virus infection. Nutr Res 2002;22:527-38.
Silliman CC, Peterson VM, Mellman DL, et al. Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: a randomized, double-blind study of the dose-response relationship. J Lab Clin Med 1993;122:48-54. View abstract.
Simkin PA. Oral zinc sulphate in rheumatoid arthritis. Lancet 1976;2:539-42. View abstract.
Singh BB, Udani J, Vinjamury Sp, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev 2005;10:123-7. View abstract.
Sjogren A, Floren CH, Nilsson A. Evaluation of zinc status in subjects with Crohn's disease. J Am Coll Nutr 1988;7:57-60. View abstract.
Smit AJ, Hoorntje SJ, Donker AJ. Zinc deficiency during captopril treatment. Nephron 1983;34:196-7. View abstract.
Smith DS, Helzner EC, Nuttall CE Jr, et al. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother 1989;33:646-8. View abstract.
Smith JC, Brown ED. Effects of oral contraceptive agents on trace element metabolism - a review. In: Prasad AS (ed). Trace Elements in Human Health and Disease. Vol.II, Essential and Toxic Elements. New York: Academic Press, 1976. 315-45.
Smith W, Mitchell P, Webb K, Leeder SR. Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 1999;106:761-77. View abstract.
Solecki TJ, Aviv A, Bogden JG. Effect of a chelating drug on balance and tissue distribution of four essential metals. Toxicology 1984;31:207-16. View abstract.
Solomons NW, Jacob RA. Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc. Am J Clin Nutr 1981;34:475-82.. View abstract.
Sorensen JA, Andersen O. Effects of diethyldithiocarbamate and tetrathylthiuram disulfide on zinc metabolism in mice. Pharmacol Toxicol 1989;65:209-13. View abstract.
Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.. View abstract.
Sprenger KB, Bundschu D, Lewis K, et al. Improvement of uremic neuropathy and hypogeusia by dialysate zinc supplementation: a double-blind study. Kidney Int Suppl 1983;16:S315-8. View abstract.
Stephen KW, Saxton CA, Jones CL, et al. Control of gingivitis and calculus by a dentifrice containing a zinc salt and triclosan. J Periodontol 1990;61:674-9. View abstract.
Strause L, Saltman P, Smith KT, et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr 1994;124:1060-4. View abstract.
Stromberg HE, Agren MS. Topical zinc oxide treatment improves arterial and venous leg ulcers. Br J Dermatol 1984;111:461-8. View abstract.
Stur M, Tittl M, Reitner A, Meisinger V. Oral zinc and the second eye in age-related macular degeneration. Invest Ophthalmol Vis Sci 1996;37:1225-35. View abstract.
Sturniolo GC, Mestriner C, Irato P, et al. Zinc therapy increases duodenal concentrations of metallothionein and iron in Wilson's disease patients. Am J Gastroenterol 1999;94:334-8. View abstract.
Sturniolo GC, Montino MC, Rossetto L, et al. Inhibition of gastric acid secretion reduces zinc absorption in man. J Am Coll Nutr 1991;10:372. View abstract.
Svatun B, Saxton CA, Huntington E, Cummins D. The effects of a silica dentifrice containing Triclosan and zinc citrate on supragingival plaque and calculus formation and the control of gingivitis. Int Dent J 1993;43:431-9. View abstract.
Svatun B, Saxton CA, Rolla G. Six-month study of the effect of a dentifrice containing zinc citrate and triclosan on plaque, gingival health, and calculus. Scand J Dent Res 1990;98:301-4. View abstract.
Swardfager W, Herrmann N, Mazereeuw G, Goldberger K, Harimoto T, Lanctôt KL. Zinc in depression: a meta-analysis. Biol Psychiatry. 2013 Dec 15;74(12):872-8. View abstract.
Swe KM, Abas AB, Bhardwaj A, Barua A, Nair NS. Zinc supplements for treating thalassaemia and sickle cell disease. Cochrane Database Syst Rev. 2013 Jun 28;6:CD009415. View abstract.
Sweeney JD, Ziegler P, Pruet C, Spaulding MB. Hyperzincuria and hypozincemia in patients treated with cisplatin. Clin Nephrol 1982;17:254-7. View abstract.
Takkouche B, Regueira-Mendez C, Garcia-Closas R, et al. Intake of vitamin C and zinc and risk of common cold: a cohort study. Epidemiology 2002;13:38-44.. View abstract.
Tang AM, Graham NM, Saah AJ. Effects of micronutrient intake on survival in human immunodeficiency virus type 1 infection. Am J Epidemiol 1996;143:1244-56. View abstract.
Tang X, Shay NF. Zinc has an insulin-like effect on glucose transport mediated by phosphoinositol-3-kinase and Akt in 3T3-L1 fibroblasts and adipocytes. J Nutr 2001;131:1414-20. View abstract.
Terrin G, Berni Canani R, Passariello A, Messina F, Conti MG, Caoci S, Smaldore A, Bertino E, De Curtis M. Zinc supplementation reduces morbidity and mortality in very-low-birth-weight preterm neonates: a hospital-based randomized, placebo-controlled trial in an industrialized country. Am J Clin Nutr. 2013 Dec;98(6):1468-74. View abstract.
The Age-Related Eye Disease Study (AREDS) Research Group. The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the age-related eye disease study: AREDS Report No. 7. J Nutr 2002;132:697-702. View abstract.
Thomas DJ, Chisholm JJ. Lead, zinc, and copper decorporation during calcium disodium ethylenediamine tetraacetate treatment of lead-poisoned children. J Pharmacol Exp Ther 1986;239:829-35. View abstract.
Tisdall FF, Brown A, Defries RD. Persistent anosmia following zinc sulfate nasal spraying. JPed 1938;18:60-2.
Toren P, Eldar S, Sela BA, et al. Zinc deficiency in attention-deficit hyperactivity disorder. Biol Psychiatry 1996;40:1308-10. View abstract.
Traikovich SS. Use of topical ascorbic acid and its effects on photodamaged skin topography. Arch Otolaryngol Head Neck Surg 1999;125:1091-8. View abstract.
Turk S, Bozfakioglu S, Ecder ST, et al. Effects of zinc supplementation on the immune system and on antibody response to multivalent influenza vaccine in hemodialysis patients. Int J Artif Organs 1998;21:274-278.. View abstract.
Turner RB, Cetnarowski WE. Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds. Clin Infect Dis 2000;31:1202-8.. View abstract.
Turner RB. Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds. Clin Infect Dis 2001;33:1865-70. View abstract.
Turner RB. The treatment of rhinovirus infections: progress and potential. Antiviral Res 2001;49:1-14.. View abstract.
Tyrer LB. Nutrition and the pill. J Reprod Med 1984;29:547-50.. View abstract.
Uebayashi H, Hatanaka T, Kanemura F, Tonosaki K. Acute anosmia in the mouse: behavioral discrimination among the four basic taste substances. Physiol Behav 2001;72:291-6.. View abstract.
Umeta M, West CE, Haidar J, et al. Zinc supplementation and stunted infants in Ethiopia: a randomised controlled trial. Lancet 2000;355:2021-6. View abstract.
Uysal Z, Akar N, Kemahli S, et al. Desferrioxamine and urinary zinc excretion in beta-thalassemia major. Pediatr Hematol Oncol 1993;10:257-60. View abstract.
Valberg LS, Flanagan PR, Chamberlain MJ. Effects of iron, tin, and copper on zinc absorption in humans. Am J Clin Nutr 1984;40:536-41.. View abstract.
van de Wal Y, van der Sluys Veer A, Verspaget HW, et al. Effect of zinc therapy on natural killer cell activity in inflammatory bowel disease. Aliment Pharmacol Ther 1993;7:281-6. View abstract.
van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA 2005;294:3101-7. View abstract.
VandenLangenberg GM, Mares-Perlman JA, Klein R, et al. Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study. Am J Epidemiol 1998;148:204-14. View abstract.
Verrotti A, Basciani F, Trotta D, et al. Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy. Epilepsy Res 2002;48:71-5. View abstract.
Vir SC, Love AH. Zinc and copper nutriture of women taking oral contraceptive agents. Am J Clin Nutr 1981;34:1479-83. View abstract.
Von Hoff DD. Phase I trials of dexrazoxane and other potential applications for the agent. Semin Oncol 1998;25:31-6. View abstract.
Walldius G, Michaelsson G, Hardell LI, Aberg H. The effects of diet and zinc treatment on the fatty acid composition of serum lipids and adipose tissue and on serum lipoproteins in two adolescent patients with acrodermatitis enteropathica. Am J Clin Nutr 1983;38:512-22. View abstract.
Watkins DW, Khalafi R, Cassidy MM, Vahouny GV. Alterations in calcium, magnesium, iron, and zinc metabolism by dietary cholestyramine. Dig Dis Sci 1985;30:477-82.. View abstract.
Watson AR, Stuart A, Wells FE, et al. Zinc supplementation and its effect on taste acuity in children with chronic renal failure. Hum Nutr Clin Nutr 1983;37:219-25. View abstract.
Webb JL. Nutritional effects of oral contraceptive use: A review. J Reprod Med 1080;25:150. View abstract.
Weismann K, Hoyer H. Serum zinc levels during oral glucocorticoid therapy. J Invest Dermatol 1986;86:715-6. View abstract.
Weismann K, Jakobsen JP, Weismann JE, et al. Zinc gluconate lozenges for common cold. A double-blind clinical trial. Dan Med Bull 1990;37:279-81. View abstract.
Weismann K, Wadskov S, Sondergaard J. Oral zinc sulphate therapy for acne vulgaris. Acta Derm Venereol 1977;57:357-60. View abstract.
Weismann K. Chelating drugs and zinc. Dan Med Bull 1986;33:208-11. View abstract.
Wester PO. Urinary zinc excretion during treatment with different diuretics. Acta Med Scand 1980;208:209-12. View abstract.
Whitney E, Cataldo CB, Rolfes SR, eds. Understanding Normal and Clinical Nutrition. Belmont, CA: Wadsworth, 1998.
Whittaker P. Iron and zinc interactions in humans. Am J Clin Nutr 1998;68:442S-6S. View abstract.
Wilkinson EA, Hawke CI. Oral zinc for arterial and venous leg ulcers. Cochrane Database Syst Rev 2000;2:CD001273. View abstract.
Williams C, McBride S, Mostler K, et al. Efficacy of a dentifrice containing zinc citrate for the control of plaque and gingivitis: a 6-month clinical study in adults. Compend Contin Educ Dent 1998;19:4-15. View abstract.
Wise A. Phytate and zinc bioavailability. Int J Food Sci Nutr 1995;46:53-63. View abstract.
Wittes J, Musch DC. Should we test for genotype in deciding on age-related eye disease study supplementation? Ophthalmology. 2015 Jan;122(1):3-5. View abstract.
Wong WY, Merkus HM, Thomas CM, et al. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Fertil Steril 2002;77:491-8.. View abstract.
Wood RJ, Zheng JJ. High dietary calcium intakes reduce zinc absorption and balance in humans. Am J Clin Nutr 1997;65:1803-9. View abstract.
Wray D. A double-blind trial of systemic zinc sulfate in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1982;53:469-72. View abstract.
Young B, Ott L, Kasarskis E, et al. Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. J Neurotrauma 1996;13:25-34. View abstract.
Yousefi A, Khani Khoozani Z, Zakerzadeh Forooshani S, Omrani N, Moini AM, Eskandari Y. Is topical zinc effective in the treatment of melasma? A double-blind randomized comparative study. Dermatol Surg. 2014 Jan;40(1):33-7. View abstract.
Yuen WC, Whiteoak R, Thompson RP. Zinc concentrations in leucocytes of patients receiving antiepileptic drugs. J Clin Pathol 1998;41:553-5. View abstract.
Yunice AA, Czerwinski AW, Lindeman RD. Influence of synthetic corticosteroids on plasma zinc and copper levels in humans. Am J Med Sci 1981;282:68-74. View abstract.
Zaichick VY, Sviridova TV, Zaichick SV. Zinc concentration in human prostatic fluid: normal, chronic prostatitis, adenoma and cancer. Int Urol Nephrol 1996;28:687-94. View abstract.
Zaichick VYe, Sviridova TV, Zaichick SV. Zinc in the human prostate gland: normal, hyperplastic and cancerous. Int Urol Nephrol 1997;29:565-74. View abstract.
Zarembo JE, Godfrey JC, Godfrey NJ. Zinc(II) in saliva: determination of concentrations produced by different formulations of zinc gluconate lozenges containing common excipients. J Pharm Sci 1992;81:128-30.. View abstract.
Zavaleta N, Caulfield LE, Garcia T. Changes in iron status during pregnancy in peruvian women receiving prenatal iron and folic acid supplements with or without zinc. Am J Clin Nutr 2000;71:956-61. View abstract.
Zemel BS, Kawchak DA, Fung EB, et al. Effect of zinc supplementation on growth and body composition in children with sickle cell disease. Am J Clin Nutr 2002;75:300-7. View abstract.
Zhou JR, Erdman JW Jr. Phytic acid in health and disease. Crit Rev Food Sci Nutr 1995;35:495-508. View abstract.
Zittel S, Ufer F, Gerloff C, Münchau A, Rosenkranz M. Severe myelopathy after denture cream use--is copper deficiency or excess zinc the cause? Clin Neurol Neurosurg. 2014 Jun;121:17-8. View abstract.
Zoli A, Altomonte L, Caricchio R, et al. Serum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1 beta and tumour necrosis factor alpha. Clin Rheumatol 1998;17:378-82. View abstract.
Zumkley H, Bertram HP, Preusser P, et al. Renal excretion and magnesium and trace elements during cisplatin treatment. Clin Nephrol 1982;17:254. View abstract.
Zumkley H, Bertram HP, Vetter H, et al. Zinc metabolism during captopril treatment. Horm Metab Res 1985;17;256-8. View abstract.