Zithranol Cream

Last updated on RxList: 6/17/2019
Zithranol Cream Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/17/2019

Zithranol-RR (anthralin cream) is an antipsoriatic medication used to treat long-term psoriasis. Zithranol-RR is available in generic form. Common side effects of Zithranol-RR include:

  • temporary redness or irritation where the medicine is applied,
  • temporary discoloration of fingernails or skin, and
  • temporary discoloration of gray/white hair

Zithranol-RR may also stain fabrics.

Apply a thin layer dose of Zithranol-RR to the affected area once daily or as directed by your doctor. Follow your doctor's directions for how long to leave Zithranol-RR on the skin/scalp before removing it. Zithranol-RR may interact with other skin products or shampoos used for psoriasis and corticosteroids. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Zithranol-RR; it is unknown how it would affect a fetus. It is unknown if Zithranol-RR passes into breast milk. Consult your doctor before breastfeeding.

Our Zithranol-RR (anthralin cream) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Zithranol Cream Professional Information


Very few instances of contact allergic reactions to anthralin have been reported. Transient primary irritation and staining of normal or uninvolved skin surrounding the treated lesions, which is frequently seen with other anthralin preparations is less common with Zithranol-RR due to microcrystalline coating of the anthralin particles. If the initial treatment produces excessive soreness or if the lesions spread, reduce frequency of application and, in extreme cases, discontinue use and consult a physician. Some temporary discoloration of hair and fingernails may arise during the period of treatment but should be minimized by careful application. Staining of fabrics may be permanent, so contact should be avoided.

Read the entire FDA prescribing information for Zithranol Cream (Anthralin Microcrystalline Encapsulated Cream)


Types of Psoriasis: Medical Pictures and Treatments See Slideshow

© Zithranol Cream Patient Information is supplied by Cerner Multum, Inc. and Zithranol Cream Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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