Zithromax vs. Bactrim

Are Bactrim and Zithromax the Same Thing?

Zithromax Z-PAK (azithromycin) and Bactrim (sulfamethoxazole and trimethoprim) are antibiotics used to treat bacterial infections.

Zithromax and Bactrim belong to different antibiotic drug classes. Zithromax is a macrolide antibiotic and Bactrim is a combination of a sulfonamide antibiotic (a “sulfa” drug) and a folic acid inhibitor.

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What Are Possible Side Effects of Zithromax?

Common side effects of Zithromax include:

What Are Possible Side Effects of Bactrim?

Common side effects of Bactrim include:

  • loss of appetite,
  • nausea,
  • vomiting,
  • painful or swollen tongue,
  • dizziness,
  • spinning sensation,
  • ringing in your ears,
  • tiredness, or
  • sleep problems (insomnia).

Tell your doctor if you experience serious side effects of Bactrim including:

What is Zithromax?

Zithromax Z-PAK (azithromycin) is a semi-synthetic macrolide antibiotic used for treating:

Zithromax is also effective against several sexually transmitted infectious diseases (STDs) such as nongonococcal urethritis and cervicitis. Zithromax is available in generic form.

What is Bactrim?

Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA), and other bacterial infections susceptible to this antibiotic. Bactrim is available as a generic drug.

What Drugs Interact With Zithromax?

Zithromax may interact with arsenic trioxide, cyclosporine, pimozide, tacrolimus, theophylline, warfarin, other antibiotics, antidepressants, anti-malaria medications, cholesterol-lowering medicines, ergot medicines, heart or blood pressure medications, heart rhythm medicines, HIV medicines, medicine to prevent or treat nausea and vomiting, medicines to treat psychiatric disorders, migraine headache medicines, narcotics, sedatives, tranquilizers, or seizure medicines. Tell your doctor all medications and supplements you use.

What Drugs Interact With Bactrim?

Bactrim may interact with blood thinners, cyclosporine, methotrexate, oral diabetes medications, and seizure medications. Bactrim may also interact with antidepressants, digoxin, diuretics (water pills), indomethacin, leucovorin, calcium folinate, and heart or blood pressure medications. Cipro may also interact clozapine, probenecid, ropinirole, theophylline, NSAIDs (nonsteroidal anti-inflammatory drugs), or steroids.

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How Should Zithromax Be Taken?

A typical oral dose of Zithromax consists of 500 mg for 1 day then 250 mg for 4 days. A typical intravenous dose consists of 500 mg for 2 days followed by 500 mg orally daily for an additional 5-8 days.

How Should Bactrim Be Taken?

Administer the solution by intravenous infusion over a period of 60 to 90 minutes. Avoid administration by rapid infusion or bolus injection. Do NOT administer Bactrim intramuscularly.

Disclaimer

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References

RxList. Zithromax Prescribing Information.
https://www.rxlist.com/zithromax-drug.htm
RxList. Bactrim Prescribing Information.
https://www.rxlist.com/bactrim-drug.htm

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