Zonatuss Side Effects Center

Last updated on RxList: 12/15/2021
Zonatuss Side Effects Center

What Is Zonatuss?

Zonatuss (benzonatate capsule) is a non-narcotic oral antitussive (anti-cough) drug indicated for the symptomatic relief of cough.

What Are Side Effects of Zonatuss?

Common side effects of Zonatuss include:

  • drowsiness
  • headache
  • dizziness
  • confusion
  • visual hallucinations
  • stomach upset
  • nausea
  • constipation
  • itching
  • skin breakouts
  • stuffy nose
  • burning sensation in the eyes
  • chilly sensation
  • numbness of the chest, or
  • hypersensitivity reactions

Dosage for Zonatuss

The dose of Zonatuss for adults and children over 10 years of age is one 150 mg capsule three times a day as needed for cough.

What Drugs, Substances, or Supplements Interact with Zonatuss?

Zonatuss may interact with other drugs. Tell your doctor all medications and supplements you use.

Zonatuss During Pregnancy or Breastfeeding

During pregnancy, Zonatuss should be used only if prescribed; it is unknown if it would harm a fetus. It is unknown if Zonatuss passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Zonatuss (benzonatate capsule) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Cold and Flu: Finding Relief for Your Cough See Slideshow
Zonatuss Consumer Information

Stop taking this medicine and get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe drowsiness or dizziness;
  • confusion, hallucinations.
  • ongoing numbness or tingling in your mouth, throat, or face;
  • numbness in your chest;
  • a choking feeling;
  • chills; or
  • burning in your eyes.

Some of these side effects may result from chewing or sucking on a benzonatate capsule.

Common side effects may include:

  • headache, dizziness;
  • nausea, upset stomach;
  • constipation;
  • itching, rash; or
  • stuffy nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Zonatuss (Benzonatate Capsules, USP 150 mg)


Which illness is known as a viral upper respiratory tract infection? See Answer
Zonatuss Professional Information


Potential Adverse Reactions to benzonatate may include

Hypersensitivity reactions including bronchospasm, laryngospasm, cardiovascular collapse possibly related to local anesthesia from chewing or sucking the capsule.

CNS: sedation; headache; dizziness; mental confusion; visual hallucinations.

GI: constipation; nausea; GI upset.

Dermatologic: pruritus; skin eruptions.

Other: nasal congestion; sensation of burning in the eyes; vague “chilly” sensation; numbness of the chest; hypersensitivity.

Deliberate or accidental overdose has resulted in death, particularly in children.

Read the entire FDA prescribing information for Zonatuss (Benzonatate Capsules, USP 150 mg)

© Zonatuss Patient Information is supplied by Cerner Multum, Inc. and Zonatuss Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors