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Zyprexa vs. Clozaril

Are Zyprexa and Clozaril the Same Thing?

Zyprexa (olanzapine) and Clozaril (clozapine) are antipsychotic medications used to treat schizophrenia.

A difference is Zyprexa is also used to treat manic episodes of bipolar disorder.

Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

What Are Possible Side Effects of Zyprexa?

Common side effects of Zyprexa include:

Tell your doctor if you experience serious side effects of Zyprexa including:

What Are Possible Side Effects of Clozaril?

Common side effects of Clozaril include:

What Is Zyprexa?

Zyprexa (olanzapine) is an atypical antipsychotic medication used to treat schizophrenia and manic episodes of bipolar disorder.

What Is Clozaril?

Clozaril (clozapine) is an antipsychotic medication that is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

SLIDESHOW

Schizophrenia: Symptoms, Types, Causes, Treatment See Slideshow

What Drugs Interact With Zyprexa?

Zyprexa may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Zyprexa may also interact with carbamazepine, diazepam, fluoxetine, olanzapine, fluvoxamine, omeprazole, rifampin, or medications to treat Parkinson's disease.

What Drugs Interact With Clozaril?

Clozaril may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Clozaril may also interact with alcohol, other antipsychotic medications, armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, phenobarbital and other barbiturates, St. John's wort, tacrolimus, antibiotics, antifungals, anti-malaria medications, atropine, belladonna, clidinium, dicyclomine, scopolamine, heart or blood pressure medications, HIV/AIDS medications, medicines to prevent or treat nausea and vomiting, and migraine headache medicines.

How Should Zyprexa Be Taken?

The recommended starting dose of Zyprexa is six grams a day for the first 48 to 72 hours of treatment. Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Zyprexa may interact with pyridostigmine, donepezil, galantamine, rivastigmine, or tacrine. Tell your doctor all prescription and over-the-counter medications and supplements you use. Zyprexa should be used during pregnancy only when prescribed. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Clozaril Be Taken?

For most patients, the recommended dose of Clozaril is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Clozaril for periods longer than two or three weeks is not recommended.

QUESTION

Schizophrenia is the most disabling mental illness. See Answer
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You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

RxList. Zyprexa Side Effects Drug Center.
https://www.rxlist.com/zyprexa-side-effects-drug-center.htm
RxList. Clozaril Prescribing Information.
https://www.rxlist.com/clozaril-side-effects-drug-center.htm
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