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Zyrtec vs. Xyzal

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Zyrtec and Xyzal the Same Thing?

Zyrtec (cetirizine hydrochloride) and Xyzal (levocetirizine dihydrochloride) antihistamines that treat symptoms such as itching, runny nose, watery eyes, and sneezing from hay fever (allergic rhinitis) and other allergies, such as allergies to molds and dust mites. Both Zyrtec and Xyzal are available over-the-counter (OTC).

What Are Possible Side Effects of Zyrtec?

Common side effects of Zyrtec include:

  • drowsiness,
  • fatigue,
  • tired feeling,
  • dizziness,
  • dry mouth,
  • sore throat,
  • cough,
  • nausea,
  • constipation, or
  • headache.

In children, side effects of Zyrtec include:

  • stomach pain and
  • vomiting.

The side effect of sleepiness may occur when taking Zyrtec, so do not drive a car or operate potentially dangerous machinery.

What Are Possible Side Effects of Xyzal?

Common side effects of Xyzal include:

  • drowsiness,
  • fatigue,
  • weakness,
  • tired feeling,
  • stuffy nose,
  • sinus pain,
  • sore throat,
  • cough,
  • vomiting,
  • diarrhea,
  • constipation,
  • dry mouth, or
  • weight gain

Tell your doctor if you have serious side effecs of Xyzal including:

  • lightheadedness,
  • nosebleeds (especially in a child),
  • pain or fullness in your ear,
  • hearing problems,
  • depression,
  • agitation,
  • aggression,
  • hallucinations,
  • numbness or tingling around your lips or mouth,
  • yellowing of your skin or eyes (jaundice),
  • painful or difficult urination,
  • dark-colored urine,
  • foul-smelling stools,
  • fever,
  • stomach pain, or
  • loss of appetite

What is Zyrtec?

Zyrtec is medication that temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:

What is Xyzal?

Xyzal is a medicaiton that is used to treat allergy symptoms associated with hay fever. Xyzal is also used to treat hives.

What Drugs Interact With Zyrtec?

Zyrtec may interact with alcohol, other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

What Drugs Interact With Xyzal?

Xyzal may interact with alcohol, other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Xyzal may also interact with ritonavir or theophylline.

How Should Zyrtec Be Taken?

Adults and children 6 years and over should take one 10 mg capsule once daily; do not take more than one 10 mg capsule in 24 hours. A 5 mg product may be appropriate for less severe symptoms.

Adults 65 years of age or older, children under 6 years of age, and consumers with liver or kidney disease should consult a doctor before using this product.

How Should Xyzal Be Taken?

Xyzal is available as 2.5 mg/5 mL (0.5 mg/mL) oral solution and as 5 mg breakable (scored) tablets, allowing for the administration of 2.5 mg, if needed. Xyzal can be taken without regard to food consumption.

Reviewed on 10/23/2018

References:
RxList. Zyrtec Product Information.
https://www.rxlist.com/zyrtec-drug.htm#description
Xyzal Product Information.
http://xyzal.com/hcp/

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