Zyvox vs. Penicillin-VK

Are Zyvox and Penicillin-VK the Same Thing?

Penicillin V potassium (penicillin VK) and vancomycin are antibiotics used to treat mild to moderately severe infections due to susceptible Gram-positive infections.

Vancomycin is also used to treat Clostridium difficile-associated diarrhea.

Side effects of Penicillin VK and vancomycin that are similar include nausea, vomiting, diarrhea, and abdominal pain.

Side effects of Penicillin VK that are different from vancomycin include stomach upset, skin rash, hives, itching, and black "hairy" tongue.

Side effects of vancomycin that are different from Penicillin VK include low blood potassium (hypokalemia), gas, fever, swelling of extremities, fatigue, urinary tract infections (UTIs), back pain, and headache.

Both Penicillin VK and vancomycin may interact with other drugs.

What Are Possible Side Effects of Zyvox?

Common side effects of Zyvox include:

Severe side effects of Zyvox include:

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow

What Are Possible Side Effects of Penicillin-VK?

Common side effects of Penicillin-VK include:

  • nausea,
  • vomiting,
  • diarrhea,
  • abdominal pain,
  • stomach upset,
  • skin rash,
  • hives,
  • itching, and
  • black "hairy" tongue.

Patients with a history of allergic reactions to other penicillins should not receive penicillin VK. Serious but rare reactions to penicillin VK include:

Penicillin VK can alter the normal bacteria in the colon and allow overgrowth of some bacteria such as Clostridium difficile, which causes inflammation of the colon (pseudomembranous colitis).

What Is Zyvox?

Zyvox (linezolid) is an antibacterial drug used to treat susceptible Gram-positive infections (for example, Staphylococcus and Streptococcus spp.). Zyvox is available in other countries under the generic name linezolid.

What Is Penicillin-VK?

Penicillin V potassium (penicillin VK) is an antibiotic used to treat mild to moderately severe infections due to penicillin G-sensitive microorganisms. Penicillin VK is available in generic form.

What Drugs Interact With Zyvox?

Zyvox may interact with MAO inhibitors, meperidine, diet pills, stimulants, cold or allergy medicines, ADHD medications, migraine or cluster headache medications, medications to treat Parkinson's disease or restless leg syndrome, antidepressants, or other medications used to treat depression, anxiety, and other psychiatric conditions. Tell your doctor all medications and supplements you use.

What Drugs Interact With Penicillin-VK?

Benemid (Probenecid) causes an increase in the level of penicillin VK in the blood by reducing the elimination of penicillin by the kidneys. Penicillin VK is considered safe during pregnancy. Penicillin VK is excreted in breast milk and may cause diarrhea or allergic responses in nursing infants.

How Should Zyvox be Taken?

Zyvox (linezolid) is available in an IV form (strength is 2mg per ml), in tablets (strengths of 400 and 600mg) and in an oral suspension (strength is 100mg per 5ml). Dose depends on the form of the drug used, the type of infection and if the drug is used to treat children or adults; the treating doctor should determine the dose. This drug is not to be used to treat Gram-negative bacterial infections. Zyvox has been used in the pediatric population with weight-adjusted dosing.

How Should Penicillin-VK be Taken?

The usual adult dose of penicillin VK is 125 to 500 mg every 6-8 hours.

QUESTION

Bowel regularity means a bowel movement every day. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Dailymed. Zyvox Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b0c75e79-bf29-4f1d-a45d-ae28398a52d9&audience=consumer

Dailymed. PENICILLIN VK Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=da74ca3c-951d-4569-b13e-d01faad1da12&audience=consumer

Health Solutions From Our Sponsors